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1.
Rev Esp Geriatr Gerontol ; 56(3): 177-182, 2021.
Artículo en Inglés | MEDLINE | ID: mdl-33642133

RESUMEN

The coronavirus disease 2019 (COVID-19) produces severe respiratory symptoms such as bilateral pneumonia associated to a high morbidity and mortality, especially in patients of advanced age. Vitamin D deficiency has been reported in several chronic conditions associated with increased inflammation and dysregulation of the immune system. Vitamin D in modulates immune function too. Vitamin D receptor (VDR) is expressed by most immune cells, including B and T lymphocytes, monocytes, macrophages, and dendritic cells and the signalling of vitamin D and VDR together has an anti-inflammatory effect. Some studies have reported that vitamin D treatment could be useful for the prevention and treatment of COVID-19 because vitamin D plays an important role as a modulator of immunocompetence. Over the last few months, some studies have hypothesized the possible beneficial effect of vitamin D supplementation in patients with COVID-19 in order to improve the immune balance and prevent the hyperinflammatory cytokine storm. Some preliminary studies have already shown promising results with vitamin D supplementation in hospitalized COVID-19 patients. Vitamin D should be administered daily until adequate levels are achieved due to vitamin D behaves as a negative acute phase reactant (APR). Despite the lack of evidence on specific doses of vitamin D to treat COVID-19 in older adults, authors consider it is necessary to standardize the use in clinical practice. These recommendations advice supplement vitamin D in a protocoled fashion based on expert opinions, level of evidence 5.


Asunto(s)
COVID-19/terapia , Síndrome de Liberación de Citoquinas , Suplementos Dietéticos , Geriatría , Deficiencia de Vitamina D/terapia , Vitamina D/administración & dosificación , Vitaminas/administración & dosificación , Anciano , COVID-19/complicaciones , COVID-19/inmunología , COVID-19/prevención & control , Síndrome de Liberación de Citoquinas/prevención & control , Humanos , Receptores de Calcitriol/metabolismo , Sociedades Médicas , España , Vitamina D/inmunología , Deficiencia de Vitamina D/complicaciones , Vitaminas/inmunología
2.
Rev Esp Geriatr Gerontol ; 44 Suppl 1: 10-4, 2009 Jun.
Artículo en Español | MEDLINE | ID: mdl-19524119

RESUMEN

Elderly people use often and in an appropriate way the Emergency Department (ED). However, we don't dispose of evidences that demonstrate utility of a specific model of geriatric assessment (GA) applied in ED. Nowadays; GA in ED should be used being adapted to the environment and with some clear objectives that allow to carry out a multidimensional diagnosis and to establish therapeutic priorities. GA contributes benefits in the continuity of care on the part of the Primary Attention when elderly people are discharged from an ED.


Asunto(s)
Servicio de Urgencia en Hospital , Evaluación Geriátrica , Anciano , Servicio de Urgencia en Hospital/estadística & datos numéricos , Humanos
3.
Rev. esp. geriatr. gerontol. (Ed. impr.) ; 44(supl.1): 10-14, jun. 2009. tab
Artículo en Español | IBECS | ID: ibc-147235

RESUMEN

Los ancianos utilizan mucho y de forma adecuada los servicios de urgencias (SU). No existen evidencias que demuestren la efectividad de un modelo concreto de valoración geriátrica (VG) aplicado en los SU. Sin embargo, la VG en los SU debería utilizarse adecuándola al entorno y con unos objetivos claros que permitan realizar un diagnóstico multidimensional y establecer prioridades terapéuticas. La VG aporta beneficios en la continuidad de cuidados por parte de la atención primaria cuando los ancianos son dados de alta de un SU (AU)


Elderly people use often and in an appropriate way the Emergency Department (ED). However, we don’t dispose of evidences that demonstrate utility of a specific model of geriatric assessment (GA) applied in ED. Nowadays; GA in ED should be used being adapted to the environment and with some clear objectives that allow to carry out a multidimensional diagnosis and to establish therapeutic priorities. GA contributes benefits in the continuity of care on the part of the Primary Attention when elderly people are discharged from an ED (AU)


Asunto(s)
Humanos , Anciano , Servicio de Urgencia en Hospital , Evaluación Geriátrica
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