Sensitivity, specificity, and cut-off points in the Brief Questionnaire for Measuring Disordered Eating Behaviors in Mexican Women.

BACKGROUND: Evidence suggests that disordered eating behaviors can result in eating disorders, which is already a reality for the Mexican population, representing an increasingly complex public health problem. Early detection is therefore essential. AIM OF THE STUDY: To obtain the sensitivity, specificity, and cut-off points of the Brief Questionnaire for Measuring Disordered Eating Behaviors to identify eating disorders in Mexican women. METHODS: The Eating Disorders Examination-Questionnaire and the Brief Questionnaire for Disordered Eating Behaviors were applied to patients diagnosed with eating disorders at two public health institutions and university students. ROC analysis was performed to determine sensitivity, specificity, predictive values, and cut-off points. RESULTS: Three cut-off points were obtained: first: eight points (Sensitivity = 60.7%, Specificity = 92.2%), showing low risk; second: 11 points (sensitivity = 24.1%; specificity = 98.9%), detecting moderate risk; and, finally, 15 points and over (sensitivity = 4.46%; specificity = 100%), indicating high risk. CONCLUSIONS: The instrument adequately identifies those individuals who are not at risk for eating disorders, making it possible to channel prevention efforts towards those who do have DEB, thus optimizing resources. LEVEL OF EVIDENCE: Level III: case-control analytic study.

When clean eating isn't as faultless: the dangerous obsession with healthy eating and the relationship between Orthorexia nervosa and eating disorders in Mexican University students.

BACKGROUND: Orthorexia Nervosa is an eating disorder that has been scarcely studied in characteristics, causes and symptoms, as well as in consequences and the relationship with other eating disorders. The present study had as its main objective the analysis of said relationship and inquisition of the possibility of predicting the development of an eating disorder from the presence of orthorexia nervosa. Also, it analyzed the differences by sex in Mexican university students. METHODS: The sample consisted of 911 university students (65.4% women and 34.6% men), between an age range of 18 to 28 years old (M = 21 and SD = 1.9). Two questionnaires were responded: the ORTO14MX, a version of the ORTO-15 instrument previously validated in Mexican students, and the EDE-Q in its short version. Besides, sociodemographic data of interest was obtained and used for this study. RESULTS: The Pearson's correlation analysis demonstrated statistically significant relations, from mild to moderate, between the factors that make up both scales, while the linear regression analysis demonstrated that 40% of the variance is explained with the factors from the ORTO-14MX scale in the overall sample for the study. Additionally, statistically significant differences were found between men and women regarding all the subscales conforming the instruments that measured orthorexia and eating disorders. CONCLUSION: These results show a moderate predictive degree, that as promising as it is, isn't conclusive. Likewise, it was confirmed that women are still more vulnerable to develop orthorexia or another eating disorder. It can be concluded that there's a vast necessity for more studies measuring the relationship between orthorexia nervosa and eating disorders, in Latinamerican samples with diverse characteristics in sociocultural backgrounds, and clinical samples.

INTRODUCCIÓN: La ortorexia nervosa es un trastorno de la conducta alimentaria que ha sido poco estudiado, tanto en sus características, causas y síntomas, como en sus consecuencias y en la relación con otros trastornos de la conducta alimentaria. El presente estudio tuvo como objetivo analizar dicha relación e indagar si es posible predecir la aparición de un trastorno de la conducta alimentaria a partir de la presencia de ortorexia nervosa, además de analizar diferencias por sexo en estudiantes universitarios mexicanos. MÉTODO: Participaron en el estudio 911 estudiantes universitarios (65.4% fueron mujeres y el 34.6% hombres), en un rango de edades entre 18 y 28 años (M = 21 y DE = 1.9) que respondieron dos cuestionarios que son: ORTO-14MX, una versión del instrumento ORTO-15 previamente validada en estudiantes mexicanos y el EDE-Q en su versión corta, además de proporcionar algunos datos sociodemográficos de interés para este estudio. RESULTADOS: El análisis de correlación de Pearson reveló relaciones estadísticas significativas de leves a moderadas entre los factores que componen ambas escalas, mientras que el análisis de regresión lineal mostró un que un 40% de la varianza es explicada a partir de los factores que componen la escala ORTO-14MX en la muestra de estudio. Adicionalmente se encontraron diferencias estadísticamente significativas entre hombres y mujeres con respecto a todas las subescalas de los instrumentos que midieron ortorexia y trastornos de la conducta alimentaria. CONCLUSIONES: Estos resultados mostraron un grado de predicción moderada que sí bien es prometedora, no resulta totalmente concluyente. Asimismo, se confirmó que las mujeres siguen siendo más vulnerables a padecer ortorexia o un TCA. Se concluye la necesidad de continuar estudiando la relación entre la ortorexia y los TCAs, en muestras latinoamericanas con otras características socio demográficas y en población clínica.

Relación entre estatus nutricional, insatisfacción corporal y conductas alimentarias de riesgo en estudiantes de nutrición / Relationship between nutritional status, body dissatisfaction and risky eating behaviors in Nutrition students

Resumen La presión sociocultural sobre los estudiantes universitarios, y en particular los que estudian nutrición, influye de manera negativa en su imagen corporal (IC), lo que favorece la adopción de conductas alimentarias de riesgo (CAR), independientemente de su estatus nutricional (ETN). El propósito del presente trabajo fue analizar la relación entre insatisfacción corporal (INC), ETN y CAR en estudiantes de nutrición. Participaron 370 estudiantes de una universidad privada (93.5% mujeres), con edad promedio de 19.5 años (DE = 2.5). Aunque 81% de los estudiantes era normopeso, 72.3% presentaron INC. Los participantes con obesidad, sobrepeso o normopeso presentaron riesgo moderado de presentar CAR (p < .05), pero no aquellos que estaban satisfechos con su IC (p < .05). Específicamente, los estudiantes que desearon tener una silueta más delgada mostraron mayor riesgo de presentar CAR (OR = 2.97, p < .05) vs. quienes deseaban tener una más robusta (p = .76). Además, a mayor índice de masa corporal, mayor práctica de ejercicio para bajar de peso, dietas restrictivas, atracones y pérdida de control al comer (p < .05). Es necesario desarrollar intervenciones orientadas a mejorar la satisfacción corporal para prevenir CAR entre estudiantes universitarios, y con mayor énfasis en aquellos que optan por cursar la carrera de nutrición.

Abstract The sociocultural pressure on university students, and particularly those studying Nutrition, negatively influences their body image (BI), which favors the adoption of risky eating behaviors (REB), regardless of their nutritional status (NS). The purpose of this study was to describe the relationship between body dissatisfaction (BD), NS and REB in Nutrition students. A total of 370 students from a private university participated (93.5% women), with a mean age of 19.5 years (SD = 2.5). Although 81% of the students were normal weight, 72.3% had BD. Participants with obesity, overweight or normal weight had moderate risk of REB (p < .05), but not those who were satisfied with their BI (p < .05). Specifically, students who wished to have a thinner silhouette showed greater risk of REB (OR = 2.97, p < .05) vs. those who wished to have a robust silhouette (p = . 76). In addition, the higher body mass index, the more exercise to lose weight, restrictive diets, binge eating and loss of control when eating (p < .05). It is necessary to develop interventions aimed at improving body satisfaction to prevent REB among university students, with greater emphasis on those who choose Nutrition as a professional career.

Prevalence of metilentetrahidrofolate reductase C677T polymorphism,consumption of vitamins B6, B9, B12 and determination of lipidichydroperoxides in obese and normal weight Mexican population / Prevalencia del polimorfismo C677T de la metilentetrahidrofolato reductasa, consumo de las vitaminas B6, B9, B12 y determinación de hidroperóxidos lipídicos en población mexicana obesa y con peso normal

Introduction: Oxidative stress is a key factor in the development of the principal comorbidities of obesity. Methylenetetrahydrofolate reductase enzyme (MTHFR) participates in the metabolism of folate with the action of vitamins B6 and B12. The gene of MTHFR may present a single nucleotide polymorphism (SNP) at position 677 (C677T), which can promote homocysteinemia associated to the production of free radicals. Objective: To determine the frequency of SNP C677T of the MTHFR, evaluate the consumption of vitamins B6, B9, B12 and determine the concentration of plasma lipid hydroperoxides (LOOH) in obese and control groups. Methods: 128 Mexican mestizo according to their body mass index were classified as normal weight (Nw; n = 75) and obesity (ObeI-III; n = 53). Identification of SNP C677T of MTHFR was performed by PCR-RFLP technic. The consumption of vitamins B6, B9 and B12 was assessed by a validate survey. LOOH was determined as an indicator of peripheral oxidative stress. Results: There was no statistical difference in the frequency of the C677T polymorphism between the TT homozygous genotype in Nw (0.19) and ObeI-III (0.25). The frequency of T allele in Nw was 0.45 and 0.51 in ObI-III group. There were no statistical differences in the consumption of vitamins B6, B9 and B12 between Nw and ObI-III groups. The LOOH showed statistical difference (p < 0.05) between Nw and ObI-III group. Discussion: Oxidative stress is present in all grades of obesity although there were no differences in the vitamin consumption and the SNP C677T between Nw and ObeI-III groups (AU)

Introducción: El estrés oxidativo es un factor clave en el inicio y el desarrollo de las comorbilidades de la obesidad. La enzima metiltetrahidrofolato reductasa (MTHFR) participa en el metabolismo del folato con la acción de las vitaminas B9 y B12. El gen MTHFR puede presentar un polimorfismo de un solo nucleótido (SNP) en la posición 677 (C677T), que puede promover homocisteinemia asociada a la producción de radicales libres. Objetivo: Determinar la frecuencia del SNP C677T de la MTHFR, evaluar el consumo de vitaminas B6, B9, B12 y determinar la concentración de hidroperóxidos lipídicos (LOOH) en plasma en un grupo de obesos y testigo. Métodos: Se clasificaron 128 mexicanos mestizos de acuerdo a su índice de masa corporal en normopeso (Nw; n = 75) y obesidad (ObeI-III; n = 53). Se identificó el SNP C677T de la MTHFR mediante la técnica de PCR-RFLP. El consumo de vitaminas B6, B9 y B12 se evaluó mediante una encuesta validada. Se determinaron LOOH como un indicador de estrés oxidativo periférico. Resultados: No hubo diferencia estadística significativa en la frecuencia del polimorfismo C677T entre homocigotos TT en Nw (0,19) y ObeI-III (0,25). La frecuencia del alelo T en Nw fue de 0,45, y 0,51 en el grupo ObeI-III. Los LOOH mostraron diferencia estadística significativa (p < 0,05) entre Nw y ObI-III. Discusión: El estrés oxidativo está presente en todos los grados de obesidad aunque no hubo diferencia entre el consumo de vitaminas y el SNP C677T entre los grupos de Nw y ObeI-III (AU)

[Comparison of resting energy expenditure determined by indirect calorimetry and estimated by predictive formulas in women with obesity degrees I to III]. / Comparación del gasto energético en reposo determinado mediante calorimetría indirecta y estimado mediante fórmulas predictivas en mujeres con grados de obesidad I a III.

INTRODUCTION: The determination of resting energy expenditure (REE) is calculated in clinical practices by predictive formulas; however the result varies among the population due to several factors. OBJECTIVE: To compare the REE determination by indirect calorimetry and by Harris-Benedict (HB), Mifflin (MF), World Health Organization (WHO), Institute of Medicine (IOM), "Formula Rápida" (FR) and Valencia (VA) formulas, in women with obesity grades I to III. METHODS: Mexican mestizo adult women were included in the study and stratified in three groups according to their body mass index (BMI). Grade I obesity (BMI 30.0-34.9, n = 42), grade II (BMI 35.0-39.9, n = 38) and grade III (BMI > 40, n = 41). REE was determined by indirect calorimetry and by the aforementioned equations. Kruskal-Wallis ANOVA and Dunn test were used for statistical comparison and p < 0.05 was accepted as a statistical difference. RESULTS: There were no statistical difference between the REE values estimated by formulas HB, WHO and VA regarding the CI. The accuracy obtained from these formulas was 63%, 67% and 64%, respectively, when data were analyzed in a single group. The IOM, ER and MF formulas showed statistically significant difference versus the CI and their accuracy were 58%, 53%, and 54%, respectively. In grade III obesity VA (78%) and FR (71%) accuracy were the highest obtained. DISCUSSION: HB, WHO and VA formulas were the best to estimate REE in Mexican women with BMI > 30. In obesity grade III FR and VA formulas showed the best performance.

Introducción: La determinación del gasto energético en reposo (GER) se calcula cotidianamente a partir de fórmulas predictivas aunque el resultado varía dependiendo de la población. Objetivo: Comparar la determinación del GER mediante calorimetría indirecta y mediante las ecuaciones Harris-Benedict (HB), Mifflin (MF), Organización Mundial de la Salud (OMS), «Institute of Medicine¼ (IOM), Fórmula Rápida (FR) y Valencia (VA) en mujeres con grados de obesidad I a III. Métodos: Mujeres adultas mestizas mexicanas se incluyeron en el estudio y formaron 3 grupos a partir del índice de masa corporal (IMC). Obesidad grado I (IMC 30,0-34,9; n = 42), grado II (IMC 35,0-39,9; n = 38) y grado III (IMC > 40; n = 41). Se determinó el GER mediante calorimetría indirecta y mediante las ecuaciones antes señaladas. ANOVA de Kruskal-Wallis y la prueba de Dunn se emplearon para el análisis estadístico (p < 0,05 se aceptó como diferencia). Resultados: No se observó diferencia estadística entre los valores de las fórmulas HB, OMS y VA respecto a la CI. La concordancia obtenida de dichas fórmulas fue 63%, 67% y 64%, respectivamente, al analizar los datos en un solo grupo de obesidad. Asimismo, las fórmulas IOM, ER y MF mostraron diferencia estadística significativa versus la CI, siendo la concordancia 58%, 53% y 54%, respectivamente. En el grado III de obesidad la concordancia de VA (78%) y FR (71%) fue la mayor obtenida. Discusión: Las fórmulas HB, OMS y VA fueron las mejores para estimar el GER en mujeres mexicanas con IMC>30. En el grado III VA y FR muestran el mejor desempeño.

Comparación del gasto energético en reposo determinado mediante calorimetría indirecta y estimado mediante fórmulas predictivas en mujeres con grados de obesidad I a III / Comparison of resting energy expenditure determined by indirect calorimetry and estimated by predictive formulas in women with obesity degrees I to III

Introducción: La determinación del gasto energético en reposo (GER) se calcula cotidianamente a partir de fórmulas predictivas aunque el resultado varía dependiendo de la población. Objetivo: Comparar la determinación del GER mediante calorimetría indirecta y mediante las ecuaciones Harris-Benedict (HB), Mifflin (MF), Organización Mundial de la Salud (OMS), "Institute of Medicine" (IOM), Fórmula Rápida (FR) y Valencia (VA) en mujeres con grados de obesidad I a III. Métodos: Mujeres adultas mestizas mexicanas se incluyeron en el estudio y formaron 3 grupos a partir del índice de masa corporal (IMC). Obesidad grado I (IMC 30,034,9; n = 42), grado II (IMC 35,0-39,9; n = 38) y grado III (IMC > 40; n = 41). Se determinó el GER mediante calorimetría indirecta y mediante las ecuaciones antes señaladas. ANOVA de Kruskal-Wallis y la prueba de Dunn's se emplearon para el análisis estadístico (p < 0,05 se aceptó como diferencia). Resultados: No se observó diferencia estadística entre los valores de las fórmulas HB, OMS y VA respecto a la CI. La concordancia obtenida de dichas fórmulas fue 63%, 67% y 64%, respectivamente, al analizar los datos en un solo grupo de obesidad. Asimismo, las fórmulas IOM, ER y MF mostraron diferencia estadística significativa versus la CI, siendo la concordancia 58%, 53% y 54%, respectivamente. En el grado III de obesidad la concordancia de VA (78%) y FR (71%) fue la mayor obtenida. Discusión: Las fórmulas HB, OMS y VA fueron las mejores para estimar el GER en mujeres mexicanas con IMC > 30. En el grado III VA y FR muestran el mejor desempeño (AU)

Introduction: The determination of resting energy expenditure (REE) is calculated in clinical practices by predictive formulas; however the result varies among the population due to several factors. Objective: To compare the REE determination by indirect calorimetry and by Harris-Benedict (HB), Mifflin (MF), World Health Organization (WHO), Institute of Medicine (IOM), "Formula Rápida" (FR) and Valencia (VA) formulas, in women with obesity grades I to III. Methods: Mexican mestizo adult women were included in the study and stratified in three groups according to their body mass index (BMI). Grade I obesity (BMI 30.034.9, n = 42), grade II (BMI 35.0-39.9, n = 38) and grade III (BMI > 40, n = 41). REE was determined by indirect calorimetry and by the aforementioned equations. Kruskal-Wallis ANOVA and Dunn's test were used for statistical comparison and p < 0.05 was accepted as a statistical difference. Results: There were no statistical difference between the REE values estimated by formulas HB, WHO and VA regarding the CI. The accuracy obtained from these formulas was 63%, 67% and 64%, respectively, when data were analyzed in a single group. The IOM, ER and MF formulas showed statistically significant difference versus the CI and their accuracy were 58%, 53%, and 54%, respectively. In grade III obesity VA (78%) and FR (71%) accuracy were the highest obtained. Discussion: HB, WHO and VA formulas were the best to estimate REE in Mexican women with BMI > 30. In obesity grade III FR and VA formulas showed the best performance (AU)

Prevalence of metilentetrahidrofolate reductase C677T polymorphism, consumption of vitamins B6, B9, B12 and determination of lipidic hydroperoxides in obese and normal weight Mexican population.

INTRODUCTION: Oxidative stress is a key factor in the development of the principal comorbidities of obesity. Methylenetetrahydrofolate reductase enzyme (MTHFR) participates in the metabolism of folate with the action of vitamins B6 and B12. The gene of MTHFR may present a single nucleotide polymorphism (SNP) at position 677 (C677T), which can promote homocysteinemia associated to the production of free radicals. OBJECTIVE: To determine the frequency of SNP C677T of the MTHFR, evaluate the consumption of vitamins B6, B9, B12 and determine the concentration of plasma lipid hydroperoxides (LOOH) in obese and control groups. METHODS: 128 Mexican mestizo according to their body mass index were classified as normal weight (Nw; n=75) and obesity (ObeI-III; n=53). Identification of SNP C677T of MTHFR was performed by PCR-RFLP technic. The consumption of vitamins B6, B9 and B12 was assessed by a validate survey. LOOH was determined as an indicator of peripheral oxidative stress. RESULTS: There was no statistical difference in the frequency of the C677T polymorphism between the TT homozygous genotype in Nw (0.19) and ObeI-III (0.25). The frequency of T allele in Nw was 0.45 and 0.51 in ObI-III group. There were no statistical differences in the consumption of vitamins B6, B9 and B12 between Nw and ObI-III groups. The LOOH showed statistical difference (p < 0.05) between Nw and ObI­III group. DISCUSSION: Oxidative stress is present in all grades of obesity although there were no differences in the vitamin consumption and the SNP C677T between Nw and ObeI­III groups.

Introducción. El estrés oxidativo es un factor clave en el inicio y el desarrollo de las comorbilidades de la obesidad. La enzima metiltetrahidrofolato reductasa (MTHFR) participa en el metabolismo del folato con la acción de las vitaminas B9 y B12. El gen MTHFR puede presentar un polimorfismo de un solo nucleótido (SNP) en la posición 677 (C677T), que puede promover homocisteinemia asociada a la producción de radicales libres. Objetivo. Determinar la frecuencia del SNP C677T de la MTHFR, evaluar el consumo de vitaminas B6, B9, B12 y determinar la concentración de hidroperóxidos lipídicos (LOOH) en plasma en un grupo de obesos y testigo. Métodos. Se clasificaron 128 mexicanos mestizos de acuerdo a su índice de masa corporal en normopeso (Nw; n=75) y obesidad (ObeI-III; n=53). Se identificó el SNP C677T de la MTHFR mediante la técnica de PCR-RFLP. El consumo de vitaminas B6, B9 y B12 se evaluó mediante una encuesta validada. Se determinaron LOOH como un indicador de estrés oxidativo periférico. Resultados. No hubo diferencia estadística significativa en la frecuencia del polimorfismo C677T entre homocigotos TT en Nw (0.19) y ObeI-III (0.25). La frecuencia del alelo T en Nw fue de 0.45, y 0.51 en el grupo ObeI-III. Los LOOH mostraron diferencia estadística significativa (p.