[Risk factors for the development of germ cell tumors in children]. / Factores de riesgo para el desarrollo de tumores de células germinales en niños.

The search for risk factors for development of germ cell tumors (GCT) in children who lived in Mexico City (MC). A protective, observational, case-control study was conducted in children under 15 years of age resident in MC, insurer by the Mexican Institute of Social Security. The study population was selected between January 1st, 1990 and December 31st, 1994. Parents of the children were interviewed with a 230-items precoded questionnaire, validated previously with a pilot study. For analysis were obtained simple frequencies and odds ratios (OR) and 95% confidence interval (95%CI). There were 21 cases and 105 controls. The most significant risk factors were winter conception (OR = 7.6, 95% CI 1.5-39.3; P = 0.007); low parental education level (OR = 2.9, 95% CI 1.1-7.5; P = 0.026); and parental combined dust and electricity exposure before pregnancy (OR = 26, 95% CI 2.28-1291.86; P = 0.0007). during (OR8.58, 95% CI 0.89-106.55; P = 0.041) and after pregnancy (OR = 9.66, 95% CI 0.99-120.22; P = 0.027). There was a protective effect with repetitive infections during infancy. In conclusion, Winter conception is in accordance with infectious etiology theory of GCT development. The low parental education level and the combined exposure to dust and electricity are very important. The protective effect of repetitive infections and other factors make necessary more epidemiologic studies in this field.

[Puerperium with short-term hospitalization]. / Puerperio de corta estancia hospitalaria.

Seventy seven cases with discharge before 12 hours post-partum and 240 cases with discharge after 24 or more hours after delivery, were evaluated at Hospital General de México, in an observational, prospective, cohort, study in low risk deliveries. Both groups were reviewed ten days after delivery. There were no different ratios for abnormal uterine hemorrhage, urinary tract infection or endometritis. Thrombophlebitis was more frequent in early discharge patients, both statistically and clinically significant (RR3.58, CI95% 1.48-8.67, P = 0.003). This finding is discussed, as well as measures to prevent it. It is concluded that early discharge programs in low risk conditions, are convenient.

[Indomethacin in threatening premature labor. Fetal and neonatal cardiovascular effects]. / Indometacina en amenaza de parto prematuro. Efectos cardiovasculares fetales y neonatales.

At the Hospital de Ginecobstetricia del Centro Medico "La Raza", between october 1, 1990 to may 31, 1991, were attended 50 women with premature labor, with pregnancies of 30-36 week sold. They were given 100 mg of indomethacin, rectal, daily, in order to obtain arrest of the uterine activity. The mean doses given was 4 +/- 0.739. In 26 (52%) patients there were transient, fetal ductal constriction. In these patients there were high fetal heart rate variability during the ductal constriction time. No other fetal an neonatal effects were documented. It is recommended when indomethacin was given in premature labor treatment a fetal ecocardiogram and the fetal and neonatal study of the patients in research of cardiovascular side effects, included neonatal pulmonary hypertension syndrome.