RESUMEN
Purpose: To describe a case of bilateral interface fluid formation 2 years after laser-assisted in situ keratomileusis (LASIK) surgery caused by the side effect of amantadine. Observations: A 47-year-old male patient with a history of Parkinson's disease treated with amantadine who had uneventful LASIK surgery in both eyes 2 years ago, presented with a decline in vision over the past 6 weeks. Results: Best corrected vision was 20/200 and 20/400 in the right and left eye respectively. Intraocular pressures were measured within the normal range. Biomicroscopic exam showed bilateral corneal edema. Anterior segment optical coherence tomography (AS-OCT) revealed fluid accumulation within the LASIK flap interface in both corneas. The patient's corneal edema and fluid in the interface began to gradually resolve, and vision improved 2 weeks after discontinuing amantadine. Conclusions and Importance: Although there is no previous report, it is possible that amantadine may cause interface fluid formation in patients with LASIK surgery.
RESUMEN
We present 5 patients with oil-drop cataracts in whom the underlying lenticular cause of myopic regression after laser in situ keratomileusis (LASIK) had been missed by their ophthalmologists. As a result, the patients were scheduled for or had had LASIK enhancement before presentation to us. After oil-drop cataracts were diagnosed, phacoemulsification was performed successfully in at least 1 eye of all patients. These cases underscore the importance of considering lens-induced myopia in refractive surgery patients, especially those with an unstable preoperative refraction or postoperative myopic regression. Refractive surgery in these cases can unnecessarily complicate the measurement of intraocular lens strength in cataract surgery.