RESUMEN
OBJECTIVE: Assessment of Corrected Flow Time (FTc) in carotid artery has been suggested recently as a measure of intravascular volume status. This study aimed to determine the reference values of FTc in carotid artery in a normal population. METHODS: A total number of 142 healthy volunteers (73 females and 69 males) with a mean age of 36.65±10.52years were included. RESULTS: The mean FTc in carotid artery was 325.18±22.15ms0.5. The mean value of FTc differed significantly between females and males both before and after passive leg raise (PLR) (330.18±21.61ms0.5 vs. 319.88±21.62, P=0.005 before PLR, and 336.89±22.95ms0.5 vs. 326.51±21.21, P=0.006 after PLR). CONCLUSION: This study would potentially pave the way to determine clinically significant cutoff points in order to assess the diagnostic accuracy of FTc in predicting intravascular volume status and fluid therapy responsiveness.
Asunto(s)
Arterias Carótidas/fisiopatología , Enfermedad Crítica , Sistemas de Atención de Punto/normas , Ultrasonografía Doppler/normas , Adulto , Velocidad del Flujo Sanguíneo , Arterias Carótidas/diagnóstico por imagen , Femenino , Humanos , Pierna/irrigación sanguínea , Masculino , Estudios Prospectivos , Flujo Pulsátil , Valores de Referencia , Reproducibilidad de los ResultadosAsunto(s)
Dolor Abdominal/etiología , Intoxicación por Plomo/diagnóstico , Opio/efectos adversos , Manejo del Dolor/normas , Dolor Abdominal/tratamiento farmacológico , Servicio de Urgencia en Hospital/organización & administración , Enema/métodos , Humanos , Irán , Intoxicación por Plomo/tratamiento farmacológico , Manejo del Dolor/métodos , Cloruro de Sodio/farmacología , Cloruro de Sodio/uso terapéuticoRESUMEN
PURPOSE: The purpose of this study is to investigate the possible correlation between corrected flow time (FTc) in carotid artery and changes in volume status. MATERIALS AND METHODS: Ninety-three patients with end-stage renal failure who underwent fluid removal via hemodialysis were enrolled prospectively. The volume of fluid removed as well as prehemodialysis and posthemodialysis measures of FTc in the carotid artery, heart rate, and mean arterial pressure was evaluated. All imaging measurements were performed with patients at supine position, 15 minutes before and after the hemodialysis session, by evaluating the right common carotid artery at the level of the lower border of thyroid cartilage. RESULTS: The mean FTc before fluid removal was 345.07±37.19 milliseconds. This measure decreased significantly after the volume removal with a posthemodialysis mean of 307.77±31.76 milliseconds (P<.0001). There was a statistically significant and negative association between the volume of fluid removed by hemodialysis and the changes in FTc (Pearson correlation, -0.39; P<.0001). CONCLUSION: The assessment of changes in FTc of carotid artery via Doppler waveform analysis may predict the changes in intravascular volume. The use of this diagnostic modality may be an accurate and noninvasive alternative to currently available methods.