[Pathogenic action of the plague microbe on the flea Xenopsylla cheopis and the ultrastructure of the causative agent at various times of its stay in the vector]. / Patogennoe deistvie chumnogo mikroba na organizm blokhi Xenopsylla cheopis i ul'trastruktura vozbuditelia v razlichnye sroki prebyvaniia v perenoschike.

Pathology of gastro-intestinal tract of Xenopsylla cheopis fleas infected with plague microbe was determined by means of electron microscopy. Ultrastructure of plague microbe during different periods of its stay in the vector was studied.

[Macrophagic transformation inhibition phenomenon of peripheral blood mononucleocytes in breast cancer]. / Fenomen ingibirovaniia makrofagal'noi transformatsii mononuklearov perifericheskoi krovi pri rake molochnoi zhelezy.

Macrophagal transformation of mononuclear cells of peripheral blood was evaluated quantitatively in vitro. The study group included 60 patients with breast cancer stages II-IV and 50 healthy subjects. Transformation of mononuclear cells to macrophages in breast cancer patients, particularly, in advanced cases, was found to be reduced, as compared with healthy controls. The serum of cancer patients contains an inhibitor of this process. This was confirmed by mononuclear cell transformation being inhibited both in patients and controls on addition of the serum of cancer patients to both cultures. The function of tumor patients' cells was partially restored, when serum of healthy controls was added. It is suggested to use macrophagal transformation as a test for immunologic examination of tumor patients.

[The proventriculus of the Xenopsylla cheopis flea studied by scanning electron microscopy]. / Izuchenie predzheludka blokhi Xenopsylla cheopis v skaniruiushchem élektronnom mikroskope.

The proventriculus of the flea X. cheopis was studied by means of scanning electron microscopy. The external surface of the proventriculus is a rigid structure with an alveolate surface ("wasp nest") formed by muscular cords. The internal surface of the proventriculus is represented by numerous acanthae which fall close together. They have a shape of bent dens with longitudinal sharply angular edges and concave spaces between them. Some edges are crenate.

[The effect of stimulators of immunoglobulin biosynthesis on the phenomenon of lymphocyte transformation by macrophages]. / Vliianie stimuliatorov biosinteza immunoglobulinov na fenomen makrofagal'noi transformatsii limfotsitov

The effect of pyrogenal and of the adjuvant of Freund's type on transformation of blood lymphocytes into macrophagal cells was studied. Experiments were conducted on rabbits with the use of the method of lymphocyte culture in vitro. These stimulants of immunogenesis increased the intensity of the process of lymphocyte transformation in a culture. It was also noted that action of pyrogenal and of complete adjuvant of Freund's type was expressed as soon as the first day after the administration. As supposed, there existed an interrelationship between the capacity of lymphocytes to transform into cells of macrophagal type and formation of immunological response of the organism.