[Antiangiogenic agents in ARMD treatment]. / Substante antiangiogenice în tratamentul DMLV--prezentare de caz.

The aim of antiangiogenic agents in the treatment of age related senile macular degeneration is to destroy coroidian neoformation vessels by minimally affecting the central vision. We present a case of important central vision recovery after 3 intravitreal injections of Avastin. The therapeutic decision and patient monitoring have been made using imaging studies, such as OCT and AFG. A modern therapeutic approach of neovascular forms of age related macular degeneration, backed up by AFG and OCT is a modern treatment method of this disabling illness which brings patients optimal functional and structural improvement.

[Avastin in age related macular degeneration]. / Avastin in degenerescenta maculara legata de vârsta.

OBJECTIVE: The purpose of the study is to evaluate the preliminary results of the treatment with Bevacizumab (Avastin) in the neovascular (wet) form of Age-Related Macular Degeneration (AMD). MATERIAL METHOD: The study is retrospective and includes 20 consecutive patients (27 eyes) who had received Avastin intravitreally, hospitalized in the Ophthalmology Clinic from Cluj-Napoca, between September 2007-March 2009, for wet AMD. Every patient had received 3 Avastin injections, approximately one month apart. Each dosis consisted of 0.05 ml (1.25 mg) Avastin. The therapeutical effect has been evaluated by: the value of the visual acuity (VA), the foveolar thickness (FT) and the total macular volume (TMV), before and after the treatment. In order to measure the VA, the classical optotipe has been used and the FT and the TMV have been evaluated by Time Domain (TD)-OCT. The follow-up period has varied between 4-10 months. The statistical interpretation of the results has been performed by the use of the Student t test, a p value < 0.05 being considered statistically sirgnificant. RESULTS: Of the 27 treated eyes, 8 (30%) had a favorable evolution of the VA, 15 (55%)--a stationary one and 4 eyes (15%) had an unfavorable outcome. The FT decreased (favorable evolution) in 18 eyes (66.66%) and increased (unfavorable evolution) in 9 eyes (33.33%). The TMV had a favorable evolution (decrease) in 21 eyes (77.77%) and an unfavorable one (increase), in 6 eyes (22.22%). CONCLUSIONS: The quantitative evolution of the VA has been predominantly stationary (55% of the eyes). Most patients described an improvement in the quality of vision, even if the VA has remained unchanged. The evolution of the FT and of the TMV has been predominantly favorable: 66.66%, 77.77% respectively. We noted the direct correlation between the evolution of the VA and of the morphological parameters evaluated by OCT, only in 33.33% of the treated eyes.

[Cone dystrophy]. / Distrofia conurilor; caz clinic.

In this issue we present the importance of OCT in the diagnosis of macular cones dystrophy.

[New method of prismatic prescription in diplopia]. / Metoda noua de prescriere a prismelor în diplopie--bazata pe un caz clinic.

This paper presents the case of a man with resulting diplopia due to multiple lesions of the extraocular muscles after an orbital trauma. The intact ocular globe has an horizonto-vertical strabismus. Purpose was the reduction of diplopia in primary gaze. The original contribution of the authors is the new method of prescription for the prismatic lenses, for the best results in glasses execution. A mathematical model of vectorial composition for light deviation through a system of prismatic lenses, is proposed.

[Association between iris examination and general pathology]. / Corelatii între examenul irian de ansamblu si patologia generala.

PURPOSE: The research proposal is to evaluate the association between certain irian signs and general pathology of studied patients. METHOD: There were studied 57 hospitalized patients; there was taken over all their iris images, which were analyzed through iridological protocols; in the same time the pathology of these patients was noted from their records in the hospital, concordant with the clinical diagnosis; all these information were included in a database for a computerised processing. RESULTS: The correlations resulted from, shows a high connection between the irian constitution establish through iridological criteria and the existent pathology. CONCLUSIONS: Iris examination can be very useful for diagnosis of a certain general pathology, in a holistic approach of the patient.

[Correlation between iridology and general pathology]. / Corelatii între examenul irian de ansamblu si patologia generala.

PURPOSE: The research proposal is to evaluate the association between certain irian signs and general pathology of studied patients. METHOD: There were studied 57 hospitalized patients; there was taken over all their iris images, which were analyzed through iridological protocols; in the same time the pathology of these patients was noted from their records in the hospital, concordant with the clinical diagnosis; all these information were included in a database for a computerised processing. RESULTS: The correlations resulted from, shows a high connection between the irian constitution establish through iridological criteria and the existent pathology. CONCLUSIONS: Iris examination can be very useful for diagnosis of a certain general pathology, in a holistic approach of the patient.