RESUMEN
Spinal cord ischemic injury and paralysis are devastating complications after open surgical repair of thoracoabdominal aortic aneurysms. Preclinical models have been developed to simulate the clinical paradigm to better understand the neuropathophysiology and develop therapeutic treatment. Neuropathological findings in the preclinical models have not been comprehensively examined before. This systematic review studies the past 40 years of the histological findings after open surgical repair in preclinical models. Our main finding is that damage is predominantly in the grey matter of the spinal cord, although white matter damage in the spinal cord is also reported. Future research needs to examine the neuropathological findings in preclinical models after endovascular repair, a newer type of surgical repair used to treat aortic aneurysms.
Asunto(s)
Aneurisma de la Aorta Abdominal/patología , Modelos Animales de Enfermedad , Daño por Reperfusión/patología , Médula Espinal/irrigación sanguínea , Médula Espinal/patología , Animales , Aneurisma de la Aorta Abdominal/complicaciones , Aneurisma de la Aorta Abdominal/cirugía , Constricción , Perros , Sustancia Gris/patología , Humanos , Ratones , Papio , Conejos , Ratas , Daño por Reperfusión/etiología , Ovinos , Especificidad de la Especie , Traumatismos de la Médula Espinal/etiología , Traumatismos de la Médula Espinal/patología , PorcinosRESUMEN
Today, the amount of stress the correctional staff endures at work is an important issue. Research has addressed this issue, but has yielded no consensus as to a properly calibrated measure of perceptions of work stress for correctional staff. Using data from a non-random sample of correctional staff (n = 228), the Rasch model was used to assess whether a specific measure of work stress would fit the model. Results show that three items rather than six items accurately represented correctional staff perceptions of work stress.