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1.
Indian J Pathol Microbiol ; 63(4): 637-639, 2020.
Artículo en Inglés | MEDLINE | ID: mdl-33154324

RESUMEN

Ichthyosis uterus is an uncommon condition in which the entire surface of the endometrium is replaced by stratified squamous epithelium. This condition most commonly develops secondary to longstanding cervical obstruction or chronic inflammation. It is considered a benign lesion, but its association with endometrial malignancy has been reported in the literature. We are reporting a case of ichthyosis uteri with dysplasia associated with cervical intraepithelial neoplasm (CIN III). The case is reported for its rarity and to aware about neoplastic potential of ichthyosis uteri.


Asunto(s)
Endometrio/patología , Epitelio/patología , Leucoplasia/diagnóstico , Útero/patología , Anciano , Femenino , Humanos , Hiperplasia/patología , Ictiosis/patología , Leucoplasia/patología , Metaplasia/clasificación , Metaplasia/diagnóstico , Metaplasia/patología , Neoplasias Uterinas/diagnóstico , Neoplasias Uterinas/patología
4.
Diagn Cytopathol ; 37(2): 125-7, 2009 Feb.
Artículo en Inglés | MEDLINE | ID: mdl-19021218

RESUMEN

Rhinosporidium seeberi causes granulomatous inflammation of mucocutaneous sites, presenting most frequently as polypoidal lesions in the nose. Sites like the conjunctiva, trachea, nasopharnyx, skin, and genitourinary tract are less frequently involved. Primary cutaneous lesion is extremely rare. We report the fine needle aspiration cytology (FNAC) of rhinosporidiosis occurring as a primary cutaneous lesion. FNAC of polypoidal and warty skin growths on leg in a 28-year-old male revealed numerous sporangia and spores of R. seeberi. There were no mucocutaneous lesions. Histopathologic examination confirmed the diagnosis. Globular bodies in endospores of R. seeberi are specific; their demonstration confirms diagnosis of rhinosporidiosis. FNAC or scrape cytology is economical and reliable in preoperative diagnosis of suspected and unsuspected cutaneous lesions of R. seeberi.


Asunto(s)
Rinosporidiosis/diagnóstico , Rhinosporidium , Enfermedades Cutáneas Parasitarias/diagnóstico , Adulto , Animales , Biopsia con Aguja Fina , Humanos , Masculino , Rinosporidiosis/patología , Rhinosporidium/citología , Rhinosporidium/aislamiento & purificación , Piel/patología , Enfermedades Cutáneas Parasitarias/patología , Esporas Protozoarias/citología , Esporas Protozoarias/aislamiento & purificación
5.
Diagn Cytopathol ; 37(1): 45-7, 2009 Jan.
Artículo en Inglés | MEDLINE | ID: mdl-18973128

RESUMEN

Adenoid cystic carcinoma is a malignant tumor of the salivary glands. It is slow growing and is characterized by the delayed development of distant metastasis, which may develop even a decade or more after initial treatment of the primary tumor. We present the case of a 68-year-old male with complaints and radiological findings suggestive of primary hepatocellular carcinoma. However, fine-needle aspiration findings showed metastasis of adenoid cystic carcinoma. A retrospective clinical and ultrasound examination of the patient revealed a small asymptomatic enlargement of the submandibular salivary gland that was aspirated and showed features of adenoid cystic carcinoma.


Asunto(s)
Carcinoma Adenoide Quístico/secundario , Neoplasias Hepáticas/secundario , Neoplasias de las Glándulas Salivales/diagnóstico , Anciano , Biopsia con Aguja Fina , Carcinoma Adenoide Quístico/diagnóstico por imagen , Humanos , Neoplasias Hepáticas/diagnóstico por imagen , Masculino , Neoplasias de las Glándulas Salivales/diagnóstico por imagen , Neoplasias de las Glándulas Salivales/patología , Glándula Submandibular/diagnóstico por imagen , Glándula Submandibular/patología , Tomografía Computarizada por Rayos X , Ultrasonografía
6.
Indian J Pathol Microbiol ; 50(1): 25-7, 2007 Jan.
Artículo en Inglés | MEDLINE | ID: mdl-17474249

RESUMEN

Tonsillar sarcoidosis can be seen as a part of generalized sarcoidosis or in isolation. Typical non-caseating granulomas are seen in the biopsy. We present a case of isolated tonsillar sarcoidosis masquerading as chronic tonsillitis in a young female.


Asunto(s)
Histocitoquímica , Tonsila Palatina/patología , Sarcoidosis/diagnóstico , Sarcoidosis/patología , Adolescente , Biopsia , Diagnóstico Diferencial , Femenino , Humanos , Tonsilitis/diagnóstico
7.
Diagn Cytopathol ; 33(4): 252-4, 2005 Oct.
Artículo en Inglés | MEDLINE | ID: mdl-16138369

RESUMEN

Dyshormonogenetic goiter is a rare cause of congenital goiter occurring due to a lack of enzymes necessary for the synthesis of thyroid hormones. We present a case of dyshormonogenetic goiter diagnosed on cytology. Correlation with the history, clinical findings, levels of thyroid hormones and other investigations is imperative for the diagnosis. The degree of hyperplasia is severe enough to prompt a diagnosis of malignancy, particularly follicular neoplasm. An accurate diagnosis helps to constitute proper therapy and prevents surgery.


Asunto(s)
Bocio/congénito , Bocio/patología , Glándula Tiroides/patología , Adolescente , Biopsia con Aguja , Bocio/terapia , Terapia de Reemplazo de Hormonas , Humanos , Hipotiroidismo , Masculino , Hormonas Tiroideas/uso terapéutico , Tiroidectomía , Tirotropina/análisis
8.
Acta Cytol ; 47(3): 349-58, 2003.
Artículo en Inglés | MEDLINE | ID: mdl-12789913

RESUMEN

OBJECTIVE: To study the cytomorphology of eyelid tumors, correlate it with histopathology and determine the diagnostic accuracy of fine needle capillary (FNC) sampling (nonaspiration) in the evaluation of lid tumors. STUDY DESIGN: A prospective study of 70 cases of eyelid masses carried out using FNC, with confirmation by histology in 66 cases and peripheral blood smear and bone marrow examination in 3. Histology was not done in 1 case, and 11 cases were inadequate on cytology. The diagnostic accuracy of cytology was 94.73%, and false negativity was 5.17%. RESULTS: The ages of the patients ranged from 3 to 75 years, with a mean of 40.4. The male/female ratio was nearly equal (37:33). The upper eyelid was affected in 45 cases and lower lid in 25 cases. The right eye was affected in 35 cases, left eye in 34 cases and both eyes in 1 case. Fifteen benign, 35 malignant and 9 infectious/inflammatory lesions were encountered, with 11 inadequate smears. CONCLUSION: FNC sampling is an effective method of sampling eyelid tumors because it causes little discomfort to the patient and allows the operator to maintain better control over the procedure. A distinction between inflammatory, benign and malignant lesions and between the types of malignant tumors can be made.


Asunto(s)
Biopsia con Aguja/métodos , Enfermedades de los Párpados/patología , Adolescente , Adulto , Anciano , Médula Ósea/patología , Niño , Preescolar , Diagnóstico Diferencial , Errores Diagnósticos , Femenino , Humanos , Masculino , Persona de Mediana Edad , Valor Predictivo de las Pruebas , Estudios Prospectivos , Reproducibilidad de los Resultados
9.
Indian J Pathol Microbiol ; 46(3): 385-9, 2003 Jul.
Artículo en Inglés | MEDLINE | ID: mdl-15025280

RESUMEN

A prospective study of 50 cases of treated breast cancer was undertaken to evaluate the status of the contralateral breast by combined physical examination, mammographic screening and mammographically directed FNAB (triple approach method). This study was done to assess the frequency of synchronous (cancers that were simultaneously diagnosed with a tumour in ipsilateral breast) or metachronous (those that occurred in contralateral breast subsequent to first cancer and not detected at the time of treatment of first cancer) malignancy and/or presence of preneoplastic lesions in the contralateral breast. Six percent cases had palpable lump in contralateral breast (synchronous or metachronous), 10% of the cases showed mammographic abnormalities. Mammographically directed FNAB showed atypical/suspicious smears in 8% cases and malignancy in 2% cases, of which infiltrating duct carcinoma was the most frequent. In high-risk group patients triple approach method proved to be extremely important screening procedure for early detection of abnormalities in contralateral breast and helps in significantly reducing the morbidity and mortality associated with it.


Asunto(s)
Neoplasias de la Mama/diagnóstico , Neoplasias Primarias Secundarias/diagnóstico , Adulto , Biopsia con Aguja Fina , Neoplasias de la Mama/terapia , Carcinoma Ductal de Mama/diagnóstico , Femenino , Humanos , Mamografía , Estudios Prospectivos
10.
Indian J Pathol Microbiol ; 46(3): 437-40, 2003 Jul.
Artículo en Inglés | MEDLINE | ID: mdl-15025295

RESUMEN

Pneumatosis cystoides intestinalis is an uncommon condition characterized by gas filled cysts within the bowel wall. We present a case of a 40-year old male who complained of abdominal pain and distension. The clinical diagnosis was intestinal obstruction and intraoperative impression was intestinal lymphangioma. The resected segment of the bowel showed multiple thin walled, tense, air-filled cysts on the serosal surface, which collapsed with a popping sound when pricked. The histologic diagnosis was pneumatosis cystoides intestinalis. Pneumatosis cystoides intestinalis has varied clinical manifestations, course and outcome depending on its benign or fulminant form. There are varying theories regarding its pathogenesis and it is seen in association with a variety of diseases. Hence it should be interpreted with relevance to its entire clinical context, as it may not be a disease in itself but a sequel to other conditions.


Asunto(s)
Neumatosis Cistoide Intestinal/diagnóstico , Neumatosis Cistoide Intestinal/etiología , Adulto , Humanos , Masculino , Modelos Biológicos , Neumatosis Cistoide Intestinal/patología
11.
Indian J Pathol Microbiol ; 46(3): 440-2, 2003 Jul.
Artículo en Inglés | MEDLINE | ID: mdl-15025296

RESUMEN

Benign stromal fragments or extracellular matrix can be seen in aspirates of invasive carcinomas. Although well documented on histology, this feature is rarely observed on fine needle aspirates and can create diagnostic difficulties on smears. Only three such cases have been reported so far. We report two more cases where stromal fragments were seen in association with invasive squamous cell carcinoma (SCC). Two cases of biopsy proved invasive SCC of the cheek and of the larynx presented with metastases to the submandibular salivary gland and to the cervical lymph node respectively. Aspirates of the metastatic sites showed two components: one of SCC and the other benign stroma, both in close approximation with one another. Both patients were treated with radiotherapy. Biopsy of the metastatic sites was not done. Benign stromal fragments can be encountered in aspirates of invasive carcinoma. These may be cellular or myxoid. Since such stromal fragments can also be seen in salivary tumours, adnexal tumours, fibroadenoma and phylloides tumour, their presence should be interpreted in the light of clinical findings of the patient, so that an erroneous diagnosis can be avoided.


Asunto(s)
Carcinoma de Células Escamosas/secundario , Adulto , Biopsia con Aguja Fina , Carcinoma de Células Escamosas/diagnóstico , Carcinoma de Células Escamosas/patología , Humanos , Neoplasias Laríngeas , Metástasis Linfática/diagnóstico , Metástasis Linfática/patología , Masculino , Persona de Mediana Edad , Células del Estroma/patología , Neoplasias de la Glándula Submandibular/diagnóstico , Neoplasias de la Glándula Submandibular/patología , Neoplasias de la Glándula Submandibular/secundario
12.
Acta Cytol ; 46(2): 357-63, 2002.
Artículo en Inglés | MEDLINE | ID: mdl-11917585

RESUMEN

OBJECTIVE: To characterize the cytologic features of Kimura's disease and distinguish the differentiating features from those of other conditions with similar cytologic findings. STUDY DESIGN: In eight cases of Kimura's disease the cytologic features were correlated with the histologic findings. RESULTS: The cytologic features included a polymorphous lymphoid population with an admixture of significant numbers of eosinophils, fragments of collagenous tissue, endothelial cells and occasional polykaryocytes. CONCLUSION: Various conditions, both benign and malignant, may mimic Kimura's disease clinically and on smears. These have to be ruled out before making a diagnosis of Kimura's disease. The cytologic features of Kimura's disease have to be interpreted in the appropriate clinical setting in order to make a correct preoperative diagnosis.


Asunto(s)
Hiperplasia Angiolinfoide con Eosinofilia/patología , Adolescente , Adulto , Hiperplasia Angiolinfoide con Eosinofilia/diagnóstico , Biopsia con Aguja , Niño , Diagnóstico Diferencial , Femenino , Humanos , Masculino , Persona de Mediana Edad
13.
Diagn Cytopathol ; 26(1): 26-8, 2002 Jan.
Artículo en Inglés | MEDLINE | ID: mdl-11782083

RESUMEN

Spontaneous infarction is an uncommon complication occurring in fibroadenoma of the breast. Although infarction following fine-needle aspiration has been reported in the literature, to the best of our knowledge this is the first reported case where infarction was encountered on first-time aspiration. It is necessary to distinguish infarcted fibroadenoma from mastitis, duct ectasia, mammary tuberculosis, and carcinoma on cytology smears. Lack of knowledge of this entity may lead to an erroneous diagnosis of inflammatory lesion or carcinoma. We report the first case of cytological and histological findings in spontaneous infarction of fibroadenoma in 13-yr-old female.


Asunto(s)
Neoplasias de la Mama/irrigación sanguínea , Mama/irrigación sanguínea , Fibroadenoma/irrigación sanguínea , Infarto/diagnóstico , Adolescente , Biopsia con Aguja , Mama/patología , Neoplasias de la Mama/cirugía , Carcinoma/patología , Diagnóstico Diferencial , Dilatación Patológica/patología , Femenino , Fibroadenoma/cirugía , Humanos , Infarto/cirugía , Mastitis/patología
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