RESUMEN
Chondrosarcoma of sternal origin is extremely rare. Here, we present the case of a 59-year-old male who presented with gradually increasing swelling and pain over the left sternoclavicular joint which was diagnosed as chondrosarcoma of sternal origin. We also present a review of the relevant literature.
RESUMEN
Rasmussen's encephalitis is a very rare type of chronic inflammatory disease of the brain. We report a case of a nine-year-old male patient who presented with seizures and cognitive impairment for six years. An MRI of the brain revealed significant cerebral hemiatrophy. The patient was on immunoglobulin therapy. We also engage in a review of the existing literature on Rasmussen's encephalitis.
RESUMEN
Juvenile nasopharyngeal angiofibroma (JNA) is a very uncommon condition. We are presenting a case of a teenage boy with painless nasal blockage and fullness of bilateral ears for two to three months. On nasal endoscopy, a firm proliferative mass obstructing the right nasal cavity was noted. It was bleeding on touch. On contrast-enhanced computed tomography of the paranasal sinuses (CECT PNS), a diagnosis of the JNA was made based on the evidence of bony erosion and intense post-contrast enhancement. He was pre-operatively locally embolized followed by surgical resection. On follow-up, the patient was stable with no signs of recurrence.
RESUMEN
BACKGROUND: Neonatal sepsis is an important cause of morbidity and mortality among newborns. As there is paucity of literature regarding early alteration of the cerebral blood flow (CBF) in neonatal sepsis our study aims to evaluate the changes in the CBF velocities and Doppler indices in neonates with early-onset neonatal sepsis (EONS) and to evaluate the predictive accuracy of cerebral blood flow velocities (CBFV) by using ultrasound Doppler as a diagnostic marker of EONS. METHODS: This cross-sectional analytical study was conducted over a period of 2 years with 123 neonates enrolled in the study. The neonates were divided into two groups: Group I (with 54 neonates) - neonates with EONS and group II (with 69 neonates) - age-matched neonates without any signs of sepsis. Ultrasound Doppler examination was performed and the cerebral hemodynamics assessed in neonates during the first seventy two hours of life. Doppler indices and CBFV were measured in the internal carotid artery (ICA), middle cerebral artery (MCA), and vertebral artery (VA) of either side. Data were analyzed using the statistical program SPSS version 23.0 (SPSS Inc., Chicago, IL, USA). Sensitivity, specificity, positive predictive value (PPV), negative predictive value (NPV), and diagnostic accuracy were calculated at different selected cutoff values for CBFV parameters. RESULTS: Lower resistance and higher peak systolic velocity and end diastolic velocity have been documented in neonates with EONS. CONCLUSION: Our study shows that the cerebral hemodynamics in neonates with EONS is altered which can be assessed bedside by noninvasive ultrasound Doppler examination.
