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J Autism Dev Disord ; 49(6): 2337-2347, 2019 Jun.
Artículo en Inglés | MEDLINE | ID: mdl-30726535

RESUMEN

To date, the phenotypic significance of EEG abnormalities in patients with ASD is unclear. In a population affected by ASD we aimed to evaluate: the phenotypic characteristics; the prevalence of EEG abnormalities; the potential correlations between EEG abnormalities and behavioral and cognitive variables. Sixty-nine patients with ASD underwent cognitive or developmental testing, language assessment, and adaptive behavior skills evaluation as well as sleep/wake EEG recording. EEG abnormalities were found in 39.13% of patients. EEG abnormalities correlated with autism severity, hyperactivity, anger outbursts, aggression, negative or destructive behavior, motor stereotypies, intellectual disability, language impairment and self-harm. Our findings confirmed that EEG abnormalities are present in the ASD population and correlate with several associated phenotypic features.


Asunto(s)
Trastorno del Espectro Autista/diagnóstico , Trastorno del Espectro Autista/fisiopatología , Electroencefalografía/métodos , Índice de Severidad de la Enfermedad , Adolescente , Agresión/fisiología , Agresión/psicología , Trastorno del Espectro Autista/psicología , Biomarcadores , Niño , Preescolar , Estudios de Cohortes , Femenino , Humanos , Discapacidad Intelectual/diagnóstico , Discapacidad Intelectual/fisiopatología , Discapacidad Intelectual/psicología , Masculino , Proyectos Piloto , Estudios Retrospectivos , Conducta Estereotipada/fisiología , Adulto Joven
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