Educational telerehabilitation program for women with pelvic floor dysfunctions after gynecological pelvic cancer treatment: protocol study for a randomized and controlled clinical trial.

BACKGROUND: Educational and self-care measures are important for women after gynecological pelvic cancer treatment. Pelvic floor muscle training exercises (PFMT) are a conservative treatment for pelvic floor (PF) dysfunction. The purpose is to evaluate the impact of a telerehabilitation and self-care program on PF dysfunctions, reports of urinary incontinence (UI), and physical-emotional factors of participants post-treatment for gynecological pelvic cancer. METHODS: Two-arm randomized clinical trial: an intervention group (IG) will evaluate the effect of a telerehabilitation program on women undergoing clinical practice of radiotherapy for the treatment of gynecological pelvic cancer and a control group (CG) will maintain the routine. Primary outcome is the prevalence of reports of UI, which will be assessed using the International Consultation on Incontinence Questionnaire-Short Form (ICIQ-SF). The secondary outcomes will be the severity and impact of UI on quality of life, location and perception of pain intensity, presence and intensity of dyspareunia, vaginal stenosis, fecal incontinence (FI), and levels of physical activity. Statistical analysis will be performed by intention-to-treat, and multivariate mixed effects analysis will be used to compare results. DISCUSSION: Activities in the context of telerehabilitation using PFMT and self-care can represent a viable and effective solution to minimize the side effects of gynecological cancer treatment and improve women's quality of life.

Mat Pilates and belly dance: Effects on patient-reported outcomes among breast cancer survivors receiving hormone therapy and adherence to exercise.

BACKGROUND: Breast cancer treatment leads to several side effects. Exercise can help to reduce these side effects. However, it is unknown whether a mat Pilates or a belly dance intervention can improve the patient-reported outcomes of these women. OBJECTIVE: Examine the effects of a 16-week exercise intervention (mat Pilates or belly dance) on patient reported outcomes (PROs) among breast cancer survivors, at 16 weeks, six months, and 12 months; and investigate sociodemographic and clinical predictors of intervention adherence. METHODS: Seventy-four breast cancer survivors who were receiving hormone therapy were randomly allocated into mat Pilates (n = 25), belly dance (n = 25) or control group (educational sessions) (n = 24). Mat Pilates and belly dance groups received a 16-week intervention, delivered three days a week and 60 min a session. The control group received three education sessions and continue usual care. The patient reported outcomes assessed were depressive symptoms (Beck Depression Inventory), stress (Perceived Stress Scale), optimism (Life Orientation Test), fatigue (FACT-F), sleep quality (Pittsburgh Sleep Quality Index) and pain (VAS), clinical and sociodemographic characteristics, and habitual physical activity (IPAQ short). RESULTS: All three groups showed a significant improvement in fatigue, and this effect was maintained during follow-up. No significant effects were found for depressive symptoms, optimism, stress, or pain. A history of exercise prior to breast cancer and be inactive after diagnosis were significant predictors of adherence to interventions. CONCLUSION: Mat Pilates, belly dance and a few educational sessions can be effective in improving fatigue after 16 weeks of intervention. REGISTRATION: ClinicalTrials.gov (NCT03194997).

Significado do uso da prótese peniana de silicone no seguimento da braquiterapia pélvica / Significado do uso da prótese peniana de silicone no seguimento da braquiterapia pélvica / Meaning of the use of silicone penile prosthesis in the follow-up of pelvic brachytherapy

Objetivo: descrever o significado do uso da prótese peniana de silicone para dilatação vaginal no seguimento da braquiterapia em mulheres com câncer ginecológico. Método: pesquisa narrativa, realizada no Centro de Pesquisas Oncológicas, Brasil, com 34 mulheres, após braquiterapia pélvica, em seguimento no serviço de fisioterapia. Coleta de dados por entrevistas semiestruturadas, incluindo dados sociodemográficos, clínicos e o significado do uso da prótese peniana na dilatação vaginal, submetidas à análise de conteúdo e discutidas à luz do estudo From 'sex toy' to intrusive imposition. Resultados: o significado perpassa o exercício de dilatação vaginal; as dificuldades relacionadas às condições vaginais, doença, tratamento, dor, sexo, constrangimentos, preconceitos, falhas na educação em saúde; as motivações relacionam-se à busca por qualidade de vida, apoio dos companheiros e profissionais. Conclusão: a abordagem de possíveis barreiras emocionais, psicológicas, sociais e físicas deve ser planejada e executada para prevenção da estenose vaginal e melhor acolhimento.

Objective: to describe the meaning of the use of silicone penile prosthesis for vaginal dilation in the follow-up of brachytherapy in women with gynecological cancer. Method: narrative research conducted at the Centro de Pesquisas Oncológicas, Brazil, with 34 women after pelvic brachytherapy, under follow-up at the physical therapy service. Data collection through semi-structured interviews, including sociodemographic and clinical data and the significance of the use of penile prosthesis in vaginal dilation, submitted to content analysis and discussed in the light of the study From 'sex toy' to intrusive imposition. Results: the meaning permeates the vaginal dilation exercise; difficulties related to vaginal conditions, disease, treatment, pain, sex, constraints, prejudices, failures in health education; motivations are related to the search for quality of life, support of partners and professionals. Conclusion: the approach of possible emotional, psychological, social and physical barriers should be planned and executed for prevention of vaginal stenosis and better reception.

Objetivo: describir el significado del uso de una prótesis peneana de silicona para la dilatación vaginal posterior a la braquiterapia en mujeres con cáncer ginecológico. Método: investigación narrativa, realizada en el Centro de Pesquisas Oncológicas, Brasil, con 34 mujeres, después de braquiterapia pélvica, en seguimiento en el servicio de fisioterapia. Recopilación de datos a través de entrevistas semiestructuradas, incluyendo datos sociodemográficos y clínicos y el significado del uso de prótesis peneana en la dilatación vaginal, sometidos a análisis de contenido y discutidos a la luz del estudio From 'sex toy' to intrusive imposition. Resultados: el significado impregna el ejercicio de dilatación vaginal; dificultades relacionadas con condiciones vaginales, enfermedad, tratamiento, dolor, sexo, vergüenza, prejuicios, fallas en la educación para la salud; las motivaciones están relacionadas con la búsqueda de calidad de vida, apoyo de la pareja y profesionales. Conclusión: se debe planificar y ejecutar el abordaje de las posibles barreras emocionales, psicológicas, sociales y físicas para prevenir la estenosis vaginal y una mejor recepción.

An Overview on the Evidence of Physical Activity Interventions in the Health of Individuals with Head and Neck Cancer: Literature Systematic Review / Um Panorama sobre as Evidências de Intervenções de Atividade Física na Saúde de Indivíduos com Câncer de Cabeça e Pescoço: Revisão Sistemática da Literatura / Un Panorama de las Evidencias de Intervenciones de Actividad Física en la Salud de Individuos con Cáncer de Cabeza y Cuello: Revisión Sistemática de la Literatura

Introduction: Head and neck cancer is considered a global public health problem, which arises in aesthetically and functionally critical areas. The practice of physical exercise has been considered one of the significant and effective non-pharmacological strategies to minimize the physical and psychological consequences. Objective: To analyze the evidence of physical activity interventions in the physical and psychological health of individuals with head and neck cancer. Method: A systematic review was conducted blindly and independently, from March to May 2021, according to the PRISMA guidelines. The search was performed in the following databases: PubMed Central®; Cochrane Library; Web of Science, Scopus, ScienceDirect. Results: Of the 515 selected studies, 15 were included in this systematic review with a total of 670 participants aged between 18 and 76 years old. The studies included aerobic exercises, endurance, mobility, stretching, strengthening, and yoga. Conclusion: Evidence proves that physical activity interventions performed with individuals with head and neck cancer may be beneficial in the treatment and physical/psychological health of this population. This study may help new researches considering the detailed information described previously regarding the interventions applied, in addition to discussing the most used instruments with this public and indicating the modalities that are being safely performed. It is suggested that more randomized trials be conducted to obtain more concise results.

Introdução: O câncer de cabeça e pescoço é considerado um problema de saúde pública mundial, que surge em áreas cosmeticamente e funcionalmente críticas. A prática de exercício físico está sendo considerada uma das estratégias não farmacológicas significativas e eficazes a fim de minimizar as consequências físicas e psicológicas. Objetivo: Analisar as evidências de intervenções de atividade física na saúde física e psicológica de indivíduos com câncer de cabeça e pescoço. Método: Revisão sistemática de forma cega e independente, de março a maio de 2021, de acordo com as diretrizes PRISMA. A busca foi realizada nas seguintes bases de dados: PubMed Central®; Biblioteca Cochrane; Web of Science, Scopus, ScienceDirect. Resultados: Entre os 515 estudos selecionados, 15 foram incluídos nesta revisão sistemática com um total de 670 participantes com idade entre 18 e 76 anos. Os estudos incluíram exercícios aeróbicos, resistência, mobilidade, alongamento, fortalecimento e ioga. Conclusão: Evidências comprovam que intervenções de atividade física realizadas com indivíduos com câncer de cabeça e pescoço podem ser benéficas no tratamento e na saúde física/psicológica dessa população. Este estudo pode auxiliar em novas pesquisas considerando as informações detalhadas descritas anteriormente sobre as intervenções aplicadas, além de discutir os instrumentos mais utilizados com esse público e indicar as modalidades que estão sendo realizadas com segurança. Sugere-se a realização de mais ensaios randomizados para obter resultados mais concisos.

Introducción: El cáncer de cabeza y cuello es considerado un problema de salud pública a nivel mundial que se presenta en áreas estética y funcionalmente críticas. La práctica de ejercicio físico ha sido considerada una de las estrategias no farmacológicas significativas y eficaces para minimizar las consecuencias físicas y psíquicas. Objetivo: Analizar la evidencia de intervenciones de actividad física sobre la salud física y psicológica de individuos con cáncer de cabeza y cuello. Método: Revisión sistemática ciega e independiente de marzo a mayo de 2021, según las guías PRISMA. La búsqueda se realizó en las siguientes bases de datos: PubMed Central®; Biblioteca Cochrane; Web of Science, Scopus, ScienceDirect. Resultados: Entre los 515 estudios seleccionados, 15 fueron incluidos en esta revisión sistemática con un total de 670 participantes con edades entre 18 y 76 años. Los estudios incluyeron ejercicio aeróbico, resistencia, movilidad, estiramiento, fortalecimiento y yoga. Conclusión: La evidencia demuestra que las intervenciones de actividad física realizadas con individuos con cáncer de cabeza y cuello pueden ser beneficiosas en el tratamiento y la salud física/psicológica de esta población. Este estudio puede ayudar a futuras investigaciones considerando la información detallada descrita anteriormente sobre las intervenciones aplicadas, además de discutir los instrumentos más utilizados con esta audiencia e indicar las modalidades que se están realizando de forma segura. Se sugieren más ensayos aleatorios para obtener resultados más concisos.

Level of physical activity and sedentary behavior in children and adolescents diagnosed with cancer: A systematic review.

Objective: The objective of the study was to examine already published evidence on the level of physical activity and sedentary behavior in children during and after treatment for cancer. And, thusly to verify if patients are following the recommendations of the World Health Organization, United States Centers for Disease Control and Prevention and American College of Sports Medicine. Methods: The platforms for searches were EBSCO, Web of Science and PubMed. The keywords used were physical activity, sedentary behavior, children or adolescents with cancer. Results: Found 4572 articles. 16 satisfied the eligibility criteria. The most children of whom had a low level of physical activity and a high level of sedentary behavior. Conclusions: We conclude that this population showed an increase in sedentary behavior. And, it was also observed that does not have specific recommendations for this population. Already, the recommendations used for the healthy children and for chronic patients are not ideal for this population. Therefore, it is demonstrated that specific recommendations must be created for this population.

The performance of physiotherapeutic conducts in oncology patients interned in a pediatric intensive care unit: A systematic review.

Objective: The intervention of physical therapy in pediatric oncology is currently transmuting from a view based on the restriction of physical stress to an approach that advocates the practice of cardiorespiratory and motor interventions that provide a better prognosis for the patient. The objective of this study is to carry out a systematic review and to identify studies that address the performance of physical therapeutic practices in pediatric cancer patients admitted to an intensive care unit (ICU). Methods: The stage of identification and selection of articles were carried out according to what was recommended by Preferred Reporting Items for Systematic Review and Meta-analyzes, on PubMed, Medline, and Scopus platforms, based on the PICO acronym, and were classified by the PeDRO quality scale. Results: A total of 19,820 articles were found and six were acceptable according to the inclusion and exclusion criteria of the study, accounting for a total of 634 patients evaluated in the respective study. Conclusion: There is a scarcity of studies that show the reality of physical therapy practice in pediatric and neonatal ICU, with a focus on cancer patients. Most of the articles found emphasize the physiotherapeutic approach in the management of ventilation in these patients. Within this context, they show positive outcomes with the highest number of discharges, reduced mortality, increased survival, and treatment of respiratory failure. In addition, the application of non-invasive ventilation modalities proved to be more prevalent and important, both in the variables mentioned above and in the prevention of complications, such as a lower rate of patients undergoing orotracheal intubation.

Covid-19 e os Impactos na Saúde Mental dos Profissionais de Saúde que Atuam na Área da Oncologia: Revisão Sistemática da Literatura / COVID-19 and the Mental Health Impacts on Oncology Healthcare Professionals: Literature Systematic Review / Covid-19 y los Impactos en la Salud Mental de los Profesionales de la Salud que Trabajan en el Campo de la Oncología: Revisión Sistemática de la Literatura

Introdução: O ambiente oncológico, por si só, já é um local que frequentemente expõe os profissionais que ali trabalham a enfrentar vivências e experiências de sofrimento no dia a dia pelas características da própria patologia. Objetivo: Verificar e analisar as evidências do impacto da doença pelo coronavírus 2019 (covid-19) sobre a saúde mental de profissionais de saúde que atuam na área da oncologia. Método: Pesquisa realizada nas bases Web of Science, PubMed, MEDLINE via Ovid, CINAHL via EBSCO e Embase, e avaliação segundo a metodologia STROBE. Resultados: Foram incluídos nove artigos, evidenciando a fragilidade do sistema de saúde do mundo inteiro diante de uma pandemia e afetando a saúde tanto dos pacientes quanto dos profissionais de saúde, em especial os que estavam na chamada "linha de frente". Esses fatores provocaram altas cargas de tensão, medo, insegurança e insatisfação profissional. Conclusão: Estratégias de prevenção de doenças emocionais relacionadas ao trabalho específico dos profissionais de saúde que atuem na área da oncologia devem ser implementadas para preservar a saúde mental dos profissionais

Introduction: The oncological environment, by itself, is a place that often exposes professionals who work there to cope with experiences and suffering in their daily work due to the characteristics of the pathology. Objective: To verify and analyze the evidence of the impact of the coronavirus disease 2019 (COVID-19) pandemic on the mental health of oncology professionals. Method: Search at the databases Web of Science, PubMed, MEDLINE via Ovid, CINAHL via EBSCO and Embase, and evaluation according to the methodology STROBE. Results: A total of 9 articles were included, which highlighted the fragility of the health system worldwide in face of the pandemic, affecting the health of both patients and professionals, especially those who were in the "front line". These factors provoked high burden of tension, fear, insecurity and professional dissatisfaction. Conclusion: Strategies for the prevention of emotional illnesses related to the specific work of oncology health professionals must be implemented to ensure their mental health

Introducción: El entorno oncológico, por sí mismo, ya es un lugar que muchas veces expone a los profesionales que allí actúan a enfrentarse a vivencias y sufrimientos en su quehacer diario debido a las características de la propia patología. Objetivo: Verificar y analizar la evidencia sobre el impacto de la enfermedad por coronavirus 2019 (covid-19) en la salud mental de los profesionales de la salud que trabajan en el sector oncológico. Método: Búsqueda en las bases de datos Web of Science, PubMed, MEDLINE vía Ovid, CINAHL vía EBSCO y Embase, evaluada metodológicamente por STROBE. Resultados: Se incluyeron un total de nueve artículos que ponían de manifiesto la fragilidad del sistema sanitario en todo el mundo ante una pandemia y que afectaba a la salud tanto de los pacientes como de los profesionales que trabajaban en los sectores sanitarios, especialmente los que estaban en la llamada "primera línea". Estos factores provocaron altas cargas de tensión, miedo, inseguridad e insatisfacción profesional. Conclusión: Estrategias para la prevención de enfermedades emocionales relacionadas con el trabajo específico de los profesionales de la salud que actúan en la área de la oncología deben desarrollarse en entornos de salud, con el fin de garantizar la salud mental de los profesionales

Epidemiological profile of women with gynecological cancer in brachytherapy: a cross-sectional study.

OBJECTIVE: to analyze the sociodemographic and clinical profile of women with gynecological cancer in brachytherapy. METHOD: a cross-sectional study including records of 1,930 visits of women in brachytherapy assisted between 2006-2016 in Santa Catarina (Brazil). Collection was performed in 2019, in an institutional bank, submitted to frequency measurements, chi-square test, 95% confidence intervals, significance level of 0.05. RESULTS: women aged 40-59 years (47.2%), white (93.3%); with elementary school (65%); cervical cancer (78.5%); stages II-III (73.3%) figured prominently. In the comparison of staging proportions in the topography variable, a higher proportion of malignant neoplasm of cervix uteri unspecified in the grouped III-IV staging (84.6%). CONCLUSION: the profile analysis shows the need for screening and health education for prevention and/or early detection of gynecological cancers and training of nurses specialized in radiotherapy to care for women's health.

Uso do taping linfático na prevenção da formação de equimoses em abdominoplastia e lipoaspiração / Use of lymphatic taping to prevent the formation of ecchymosis in abdominoplasty and liposuction

Introdução: Uma das intercorrências mais comuns em pós-operatório de cirurgia plástica de lipoaspiração e abdominoplastia é a equimose, e seu tratamento e prevenção fazem parte da rotina do fisioterapeuta dermatofuncional. O objetivo é avaliar a ocorrência de equimose de pacientes submetidas à abdominoplastia e/ou lipoaspiração tradicional de abdome e flancos, e correlacionar estatisticamente essas ocorrências com o tratamento de taping linfático no transoperatório. Métodos: Ensaio clínico controlado, composto por 20 pacientes do sexo feminino, com idade entre 20 e 60 anos divididos em dois grupos: 10 no grupo controle (GC) e 10 no grupo experimental (GE). Todas as mulheres que apresentavam indicação cirúrgica de abdominoplastia e/ou lipoaspiração de abdome e flancos. O GC foi apenas avaliado no pré-operatório e no 4º dia de pós-operatório, enquanto o grupo GE foi avaliado no pré-operatório, recebeu tratamento transoperatório com aplicação de taping linfático e foi reavaliado no 4º dia de pósoperatório. Resultados: O grupo experimental apresentou uma melhor resposta na resolução da equimose (p=0,01) quando comparado ao grupo controle. Conclusão: Neste estudo, o uso do taping linfático no transoperatório de abdominoplastia e lipoaspiração, reduziu ou anulou a formação de equimose no pós-operatório, contribuindo para a diminuição do número de atendimentos fisioterapêuticos, incidência de quadro álgico e acelerando assim o restabelecimento dos pacientes no pósoperatório das cirurgias de abdominoplastia e/ou lipoaspiração.

Introduction: Ecchymosis is one of the most common complications in the postoperative period of plastic liposuction and abdominoplasty surgery. Its treatment and prevention are part of the routine of the dermatofunctional physiotherapist. The objective is to evaluate the occurrence of ecchymosis in patients undergoing abdominoplasty and/ or traditional liposuction of the abdomen and flanks and statistically correlate these occurrences with the treatment of lymphatic taping during the operation. Methods: Controlled clinical trial, composed of 20 female patients, aged between 20 and 60, divided into 10 in the control group (CG) and 10 in the experimental group (EG). All women had a surgical indication of abdominoplasty and/or liposuction of the abdomen and flanks. The CG was only evaluated preoperatively and on the 4th postoperative day, while the EG group was evaluated preoperatively, received transoperative treatment with application of lymphatic taping and was reevaluated on the 4th postoperative day. Results: The experimental group presented a better response in the resolution of ecchymosis (p=0.01) when compared to the control group. Conclusion: In this study, the use of lymphatic taping during the transoperative period of abdominoplasty and liposuction reduced or annulled the formation of ecchymosis in the postoperative period, contributing to the decrease in the number of physical therapy visits, the incidence of pain and thus accelerating the reestablishment of patients from abdominoplasty and/or liposuction surgeries.

Pain characteristics and quality of life of breast cancer survivors that return and do not return to work: an exploratory cross-sectional study.

PURPOSE: the aim of this study is two-fold: 1) to explore the pain characteristics among breast cancer survivors that return to work and do not return to work; 2) to identify the factors associated with pain on the upper quadrant of the affected side. MATERIALS AND METHODS: Sixty-two breast cancer survivors were included. Quality of life was assessed using EORTC QLQ-C30 and QLQ-BR23. Pain characteristics were assessed with a body diagram and a numeric rating scale. RESULTS: Thirty-five breast cancer survivors did not return to work. Ninety-one percent of women that did not return to work reported pain. The most frequent pain sites were the cervical spine and the axilla of the affected side. There were no significant differences in pain intensity between groups. The factors associated with pain on the upper quadrant of the affected side were perception of shoulder stiffness OR = 5.93 (1.38-44.87, 95%CI) and time since surgery of more than four years OR = 5.54 (1.36-20.97, 95% CI). CONCLUSIONS: Pain was highly prevalent among breast cancer survivors. Breast cancer survivors that returned to work presented better quality of life. Longer time since surgery and perception of shoulder stiffness were associated with pain on the upper quadrant of the affected side.Implications for rehabilitationPain is a major factor following breast cancer surgery preventing returning to work.This group reported more pain on the cervical spine and axilla of the affected side.Rehabilitation needs to focus specifically on pain management in order to improve quality of life.A multidisciplinary approach involving pain specialists and vocational support is recommended.

Epidemiological profile of women with gynecological cancer in brachytherapy: a cross-sectional study / Perfil epidemiológico de las mujeres com cáncer ginecológico em brachiterapia: um estúdio transversal / Perfil epidemiológico de mulheres com câncer ginecológico em braquiterapia: estudo transversal

ABSTRACT Objective: to analyze the sociodemographic and clinical profile of women with gynecological cancer in brachytherapy. Method: a cross-sectional study including records of 1,930 visits of women in brachytherapy assisted between 2006-2016 in Santa Catarina (Brazil). Collection was performed in 2019, in an institutional bank, submitted to frequency measurements, chi-square test, 95% confidence intervals, significance level of 0.05. Results: women aged 40-59 years (47.2%), white (93.3%); with elementary school (65%); cervical cancer (78.5%); stages II-III (73.3%) figured prominently. In the comparison of staging proportions in the topography variable, a higher proportion of malignant neoplasm of cervix uteri unspecified in the grouped III-IV staging (84.6%). Conclusion: the profile analysis shows the need for screening and health education for prevention and/or early detection of gynecological cancers and training of nurses specialized in radiotherapy to care for women's health.

RESUMEN Objetivo: analizar el perfil sociodemográfico y clínico de mujeres con cáncer ginecológico en braquiterapia. Método: estudio transversal que incluyó registros de 1.930 visitas de mujeres en braquiterapia asistidas entre 2006-2016 en Santa Catarina (Brasil). La recolección se realizóen 2019, en un banco institucional, sometida a medidas de frecuencia, pruebachi-cuadrado, intervalos de confianza al 95%, nivel de significancia de 0,05. Resultados: predominaron las mujeres entre 40-59 años (47,2%), blancas (93,3%); con educación primaria (65%); cáncer de cuello uterino (78,5%); en estadios II-III (73,3%). Al comparar las proporciones de estadificación en la variable topografía, encontramos una mayor proporción de malignidad cervical no especificada la estadificación agrupada III-IV (84,6%). Conclusión: el análisis del perfil muestra la necesidad de cribado y educación sanitaria para la prevención y/o detección temprana de cánceres ginecológicos y la formación de enfermeras especializadas en radioterapia para el cuidado de la salud de la mujer.

RESUMO Objetivo: analisar o perfil sociodemográfico e clínico de mulheres com câncer ginecológico em braquiterapia. Método: estudo transversal incluindo registros de 1.930 atendimentos de mulheres em braquiterapia assistidas entre 2006-2016 em Santa Catarina (Brasil). Coleta foi realizada em 2019, em banco institucional, submetida às medidas de frequência, Teste Qui-Quadrado, intervalos de 95% de confiança, nível de significância de 0,05. Resultados: predominaram as mulheres entre 40-59 anos (47,2%),brancas (93,3%); com ensino fundamental (65%); câncer do colo do útero (78,5%); nos estádios II-III (73,3%). Na comparação das proporções dos estadiamentos na variável topografia, encontrou-se uma maior proporção da neoplasia maligna do colo do útero não especificada nos estadiamentos III-IV agrupados (84,6%). Conclusão: a análise do perfil mostra a necessidade do rastreamento e educação em saúde para prevenção e/ou detecção precoce dos cânceres ginecológicos e a formação de enfermeiros especialistas em radioterapia para atendimento da saúde da mulher.

Mulheres com câncer ginecológico: significado da braquiterapia / Mujeres con cáncerginecológico: significado de la braquiterapia / Women with gynecological cancer: meaning of brachytherapy

RESUMO Objetivo: conhecer o significado da braquiterapia em mulheres com câncer ginecológico. Métodos: pesquisa qualitativa, descritiva e exploratória realizada com 32 mulheres, submetidas à braquiterapia em instituição oncológica de Santa Catarina, Brasil. Na coleta de dados, entre setembro de 2017 e julho de 2018, aplicou-se entrevista semiestruturada. As comunicações foram submetidas à análise de conteúdo, incluindo regras de enumeração para análise dos dados sociodemográficos, clínicos e para quantificação dos relatos agrupados. Publicações relacionadas com o tema e a Teoria do Conforto sustentaram teoricamente a inferência dos dados. Emergiram cinco categorias temáticas, neste artigo apresentam-se três. Resultados: a categoria "O medo e as crenças pessoais no enfrentamento do câncer ginecológico e da braquiterapia" destaca o medo da morte, o desejo pela cura e o apego à família e à religiosidade; "Medo do tratamento e desconfortos relacionados" retrata as alterações relacionadas aos contextos físico, psicológico e ambiental; "Dor como significado" revela a percepção dolorosa sentida pelas mulheres em decorrência da doença ou da braquiterapia. Conclusão: conhecer o significado da braquiterapia permite que os enfermeiros possam repensar a coleta de dados e o planejamento de enfermagem para melhor educação em saúde e redução dos desconfortos.

RESUMEN Objetivo: conocer el significado de la braquiterapia en mujeres con cáncer ginecológico. Métodos: investigación cualitativa, descriptiva y exploratoria realizada con 32 mujeres, sometidas a la braquiterapia en institución oncológica de Santa Catarina, Brasil. En la recolección de datos, entre septiembre de 2017 y julio de 2018, se aplicó entrevista semiestructurada. Los relatos fueron sometidos al análisis de contenido, incluyendo reglas de enumeración para análisis de los datos sociodemográfico, clínicos y para cuantificación de los relatos agrupados. Publicaciones relacionadas con el tema yla Teoría del Confort basaron teóricamente la inferencia de los datos. Surgieron cinco categorías temáticas, en este artículo se presentan tres. Resultados: la categoría "El miedo y las creencias personales en el enfrentamiento del cáncer ginecológico y de la braquiterapia" destaca el temor a la muerte, el deseo por la cura y el apego a la familia y a la religiosidad; "Miedo al tratamiento y las molestias relacionadas" retrata las alteraciones relacionadas a los contextos físico, psicológico y ambiental; "Dolor como significado" revela la percepción dolorosa sentida por las mujeres debido a la enfermedad o la braquiterapia. Conclusión: conocer el significado de la braquiterapia permite que los enfermeros puedan repensar la recolección de datos y la planificación de enfermería para una mejor educación en salud y reducción de las molestias.

ABSTRACT Objective: to know the meaning of brachytherapy in women with gynecological cancer. Methods: qualitative, descriptive and exploratory research conducted with 32 women who underwent brachytherapy at an oncology institution in Santa Catarina, Brazil. Data collection took place between September 2017 and July 2018 through semi-structured interviews. Communications were submitted to content analysis, including enumeration rules for the analysis of sociodemographic and clinical data and for the quantification of grouped reports. Publications related to the theme and the Comfort Theory theoretically supported the inference of the data. Five thematic categories emerged; in this article three are presented. Results: the category "Fear and personal beliefs in coping with gynecological cancer and brachytherapy" highlights the fear of death, the desire for healing and attachment to family and religiosity; "Fear of treatment and related discomforts" depicts changes related to physical, psychological and environmental contexts; "Pain as meaning" reveals the painful perception felt by women as a result of illness or brachytherapy. Conclusion: knowing the meaning of brachytherapy allows nurses to rethink data collection and nursing planning for better health education and reduction of discomfort.

Práticas de autocuidado e os efeitos colaterais imediatos em mulheres com câncer ginecológico em braquiterapia / Prácticas de autocuidado y los efectos colaterales inmediatos en mujeres con cáncer ginecológico en braquiterapia / Self-care practices and immediate side effects in women with gynecological cancer in brachytherapy

Objetivo: revelar os efeitos colaterais imediatos e as práticas de autocuidado adotadas por mulheres com câncer ginecológico submetidas à braquiterapia. Método: pesquisa narrativa, realizada com 12 mulheres, no Sul do Brasil, entre dezembro/2018 e janeiro/2019, incluindo entrevista semiestruturada submetida à análise de conteúdo. Resultados: da análise emergiram três categorias temáticas: Cuidados orientados e adotados pelas mulheres em braquiterapia pélvica; Efeitos colaterais imediatos percebidos pelas mulheres em braquiterapia pélvica; Cuidados não orientados pelos profissionais da saúde. Os cuidados orientados pelas enfermeiras mais relatados pelas mulheres foram dilatação vaginal, uso de ducha e lubrificante vaginal, consumo de chá, higienização e guarda do dilatador vaginal. Os efeitos colaterais mais citados nas entrevistas foram alterações urinárias e intestinais na pele e mucosas. Conclusão: evidencia-se que a atenção de enfermagem em braquiterapia deve priorizar cuidados para prevenir e controlar as alterações geniturinárias e tegumentares, incluindo práticas de autocuidado.

Objective: to reveal the immediate side effects and self-care practices adopted by women with gynecological cancer submitted to brachytherapy. Method: narrative research, conducted with 12 women, in southern Brazil, between December/2018 and January/2019, including semi-structured interviews submitted to content analysis. Results: three thematic categories emerged from the analysis: Care oriented and adopted by women in pelvic brachytherapy; Immediate side effects perceived by women in pelvic brachytherapy; Care not guided by health professionals. The care provided by the nurses most reported by the women was vaginal dilation, use of a shower and vaginal lubricant, tea consumption, cleaning, and storage of the vaginal dilator. The side effects most frequently mentioned in the interviews were urinary and intestinal changes in the skin and mucous membranes. Conclusion: nursing care in brachytherapy must prioritize care to prevent and control genitourinary and cutaneous changes, including self-care practices.

Objetivo: revelar los efectos colaterales inmediatos y las prácticas de autocuidado adoptadas por mujeres con cáncer ginecológico sometidas a la braquiterapia. Método: investigación narrativa, realizada con 12 mujeres, en el Sur de Brasil, entre diciembre/2018 y enero/2019, incluyendo entrevista semiestructurada sometida al análisis de contenido. Resultados: del análisis surgieron tres categorías temáticas: Cuidados orientados y adoptados por las mujeres en braquiterapia pélvica; Efectos colaterales inmediatos percibidos por las mujeres en braquiterapia pélvica; Cuidados no orientados por los profesionales de la salud. Los cuidados orientados por las enfermeras más relatados por las mujeres fueron dilatación vaginal, uso de ducha y lubrificante vaginal, consumo de té, higienización y guarda del dilatador vaginal. Los efectos colaterales más citados en las entrevistas fueron alteraciones urinarias e intestinales en la piel y mucosas. Conclusión: se observa que la atención de enfermería en braquiterapia debe priorizar cuidados para prevenir y controlar las alteraciones genitourinarias y pigmentarias, incluyendo prácticas de autocuidado.

Recommendations for Physiotherapy in Breast and Gynecological Cancer during COVID-19 Pandemic: Literature Review / Recomendações para Fisioterapia em Oncologia Mamária e Ginecológica durante a Pandemia de COVID-19: Revisão da Literatura / Recomendaciones de Fisioterapia en Oncología Mamaria y Ginecológica durante la Pandemia Covid-19: Revisión de Literatura

Introduction: Considering COVID-19 pandemic, physiotherapeutic care for breast and gynecological cancer has the challenge of continuing or beginning the treatment, preventing or treating complications. Objective: To offer guidance about physiotherapy for breast and gynecological cancer during and after the COVID-19 pandemic. Method: Descriptive study produced after a public consultation about the theme and based on literature review and opinions of a group of experts. To classify the strength of the recommendations of the outcomes included, the GRADE system was used. Results: 82 Brazilian physiotherapists responded the online survey. Most of the professionals (36.6%) reported they needed information about the use of personal protective equipment and its hygiene, 18.3%, control and prevention of lymphedema, bandaging and skin care and 17.1%, pelvic floor dysfunction. The analysis of the public consultation, literature review and expert's consensus resulted in recommendations related to the impact of the COVID-19 pandemic over the care to women undergoing breast or gynecological cancer treatment and on physiotherapy follow-up; on telephysiotherapy follow-up of the most prevalent complications; on women in palliative care and safety after resuming in-person consultation. Aspects of the decision making in relation to the format of the sessions were discussed and the criteria to return to in-person routine. Conclusion: This manuscript recommends the continuation of the physiotherapy services during and after the COVID-19 pandemic highlighting the educative and self-applied components of the sessions, prioritizing a physical activity plan and specific exercises to contribute for better quality of life of the women.

Introdução: Considerando a pandemia de Covid-19 e a assistência fisioterapêutica nos cânceres de mama e ginecológico, o desafio tem sido continuar ou iniciar a fisioterapia para prevenir ou tratar complicações. Objetivo: Oferecer recomendações voltadas à fisioterapia para os cânceres de mama e ginecológico durante o período de Covid-19. Método: Estudo descritivo produzido após consulta pública sobre o tema, baseado na revisão da literatura e nas considerações de grupo de especialistas. Para graduar a força das recomendações para os desfechos incluídos, utilizou-se o sistema GRADE. Resultados: Oitenta e dois fisioterapeutas de diferentes regiões brasileiras responderam à pesquisa, remotamente. A maioria (36,6%) relatou necessidade de informação sobre equipamento de proteção individual e sua higiene; 18,3% sobre controle e prevenção de linfedema, enfaixamento compressivo e cuidados com a pele; e 17,1% sobre disfunção do assoalho pélvico. A análise da consulta pública, revisão da literatura e considerações dos especialistas resultaram nas recomendações sobre: impacto da pandemia de Covid-19 no acompanhamento fisioterapêutico das mulheres submetidas ao tratamento oncológico mamário ou ginecológico; acompanhamento das complicações mais prevalentes por meio da telefisioterapia; atenção às mulheres em cuidados paliativos; e segurança na assistência após retorno presencial. Aspectos da tomada de decisão em relação ao formato das sessões e critérios de retorno à rotina presencial foram discutidos. Conclusão: Este manuscrito recomenda a continuidade da fisioterapia durante e após a pandemia de Covid-19, destacando componentes educativos e de autoaplicação, priorizando um plano de atividade física e exercícios específicos para contribuir para melhor qualidade de vida das mulheres.

Introducción: Considerando la pandemia de Covid-19 y la asistencia de fisioterapia en cáncer de mama y ginecológico, el desafío ha sido continuar o iniciar la fisioterapia para prevenir o tratar complicaciones. Objetivo: Ofrecer recomendaciones de fisioterapia para el cáncer de mama y ginecológico durante la pandemia. Método: Estudio descriptivo elaborado tras una consulta pública sobre el tema, basado en una revisión de la literatura y consideraciones de expertos. Para calificar la fuerza de las recomendaciones se utilizó el sistema GRADE. Resultados: Ochenta y dos fisioterapeutas brasileños respondieron a la encuesta; 36,6% refirió la necesidad de información sobre equipos de protección personal e higiene; 18,3% en el control y prevención del linfedema, vendajes compresivos y cuidado de la piel; 17,1% en disfunción del suelo pélvico. El análisis de la consulta pública, la revisión de la literatura y las consideraciones de los expertos dieron como resultado las recomendaciones sobre: impacto de la pandemia Covid-19 en el seguimiento fisioterapéutico de mujeres sometidas a tratamiento por cáncer de mama y ginecológico; seguimiento de las complicaciones más prevalentes mediante teleterapia; atención a mujeres en cuidados paliativos; y seguridad en la asistencia después del regreso en persona. Se discutieron aspectos de la toma de decisión y sen relación al formato de las sesiones y criterios para volver a la rutina presencial. Conclusión: Este manuscrito presenta algunas recomendaciones para la continuidad de la fisioterapia durante la pandemia, destacando los componentes educativos y de autorrealización de las guías, y priorizando un plan de actividad física y ejercicios específicos para contribuir con mejor calidad de vida.

Functionality and factors associated with work behaviour among Brazilian breast cancer survivors: A cross-sectional study.

BACKGROUND: Breast cancer treatments lead to several comorbidities in the upper limbs, such as pain and stiffness, hindering physical functions and the return to work. OBJECTIVE: To explore the functionality and factors associated with work behaviour among manual and non-manual Brazilian workers who have recovered from breast cancer. METHODS: This is an observational cross-sectional study involving Brazilian breast cancer survivors. The sociodemographic, work, and clinical aspects were assessed through clinical records, upper limb disability, and human functionality obtained from 62 women. Multiple and univariate logistic regressions were used to identify the association of variables on return to work, p < 0.05. RESULTS: 56.5% of women did not return to work, the mean time for returning to work was 16 months (±15.21), absenteeism from work lasted 41 months (±34.58). Modified radical mastectomy (OR = 5.13, 95% CI = 1.35 to 18.66) and moderate-to-severe disability levels in the upper limbs (OR = 6.77, 95% CI = 1.86 to 24.92) were associated with not returning to work. The loss of productivity was higher among non-manual workers (21.5%) (p = 0.040). CONCLUSIONS: The rates of not returning to work after breast cancer treatment are high. Women who did not return to work presented higher levels of disability.

Pilates and dance to patients with breast cancer undergoing treatment: study protocol for a randomized clinical trial - MoveMama study.

BACKGROUND: Breast cancer is a global public health issue. The side effects of the clinical treatment can decrease the quality of life of these women. Therefore, a healthy lifestyle is essential to minimize the physical and psychological side effects of treatment. Physical activity has several benefits for women with breast cancer, and Pilates solo and belly dancing can be an enjoyable type of physical activity for women with breast cancer undergoing clinical treatment. The purpose of this study is to provide a Pilates solo and a belly dance protocol (three times per week/16 weeks) for women undergoing breast cancer treatment and compare its effectiveness with that in the control group. METHODS: The participants will be allocated to either the intervention arm (Pilates solo or belly dance classes three times per week for 16 weeks) or a control group (receipt of a booklet on physical activity for patients with breast cancer and maintenance of habitual physical activity routine). The Pilates solo and belly dance classes will be divided into three stages: warmup and stretching, the main stage, and relaxation. Measurements of the study outcomes will take place at baseline; postintervention; and 6, 12, and 24 months after the end of the intervention (maintenance period). The data collection for both groups will occur with a paper questionnaire and tests covering general and clinical information. The primary outcome will be quality of life (EORT QLQ-C30 and EORT QLQ-BR23), and secondary outcomes will be physical aspects such as cardiorespiratory fitness (6-min walk test and cycle ergometer), lymphedema (sum of arm circumference), physical activity (IPAQ short version), disabilities of the arm (DASH), range of motion (goniometer test), muscular strength (dynamometer test) and flexibility (sit and reach test), and psychological aspects such as depressive symptoms (Beck Depression Inventory), body image (Body Image After Breast Cancer Questionnaire), self-esteem (Rosenberg), fatigue (FACT-F), pain (VAS), sexual function (FSFI), and sleep quality (Pittsburgh Sleep Quality Index). DISCUSSION: In view of the high prevalence of breast cancer among women, the implementation of a specific protocol of Pilates solo and belly dancing for patients with breast cancer is important, considering the necessity to improve their physical and psychological quality of life. Pilates solo and belly dancing are two types of physical activity that involve mental and physical concentration, music, upper limb movements, femininity, and social involvement. An intervention with these two physical activities could offer options of supportive care to women with breast cancer undergoing treatment, with the aim being to improve physical and psychological quality of life. TRIAL REGISTRATION: ClinicalTrials.gov, NCT03194997. Registration date 12 August 2017. Universal Trial Number (World Health Organization), U1111-1195-1623.

Body mass index, asthma, and respiratory symptoms: a population-based study.

OBJECTIVE: To estimate the prevalence of respiratory symptoms and asthma, according to body mass index (BMI), as well as to evaluate factors associated with physician-diagnosed asthma, in individuals ≥ 40 years of age. METHODS: This was a population-based cross-sectional study conducted in Florianópolis, Brazil, with probability sampling. Data were collected during home visits. Demographic data were collected, as were reports of physician-diagnosed asthma, respiratory symptoms, medications in use, and comorbidities. Anthropometric measurements were taken. Individuals also underwent spirometry before and after bronchodilator administration. Individuals were categorized as being of normal weight (BMI < 25 kg/m2), overweight (25 kg/m2 ≥ BMI < 30 kg/m2), or obese (BMI ≥ 30 kg/m2). RESULTS: A total of 1,026 individuals were evaluated, 274 (26.7%) were of normal weight, 436 (42.5%) were overweight, and 316 (30.8%) were obese. The prevalence of physician-diagnosed asthma was 11.0%. The prevalence of obesity was higher in women (p = 0.03), as it was in respondents with ≤ 4 years of schooling (p < 0.001) or a family income of 3-10 times the national minimum wage. Physician-diagnosed asthma was more common among obese individuals than among those who were overweight and those of normal weight (16.1%, 9.9%, and 8.0%, respectively; p = 0.04), as were dyspnea (35.5%, 22.5%, and 17.9%, respectively; p < 0.001) and wheezing in the last year (25.6%, 11.9%, and 14.6%, respectively; p < 0.001). These results were independent of patient smoking status. In addition, obese individuals were three times more likely to report physician-diagnosed asthma than were those of normal weight (p = 0.005). CONCLUSIONS: A report of physician-diagnosed asthma showed a significant association with being ≥ 40 years of age and with having a BMI ≥ 30 kg/m2. Being obese tripled the chance of physician-diagnosed asthma.

Body mass index, asthma, and respiratory symptoms: a population-based study / Índice de massa corpórea, asma e sintomas respiratórios: um estudo de base populacional

ABSTRACT Objective: To estimate the prevalence of respiratory symptoms and asthma, according to body mass index (BMI), as well as to evaluate factors associated with physician-diagnosed asthma, in individuals ≥ 40 years of age. Methods: This was a population-based cross-sectional study conducted in Florianópolis, Brazil, with probability sampling. Data were collected during home visits. Demographic data were collected, as were reports of physician-diagnosed asthma, respiratory symptoms, medications in use, and comorbidities. Anthropometric measurements were taken. Individuals also underwent spirometry before and after bronchodilator administration. Individuals were categorized as being of normal weight (BMI < 25 kg/m2), overweight (25 kg/m2 ≥ BMI < 30 kg/m2), or obese (BMI ≥ 30 kg/m2). Results: A total of 1,026 individuals were evaluated, 274 (26.7%) were of normal weight, 436 (42.5%) were overweight, and 316 (30.8%) were obese. The prevalence of physician-diagnosed asthma was 11.0%. The prevalence of obesity was higher in women (p = 0.03), as it was in respondents with ≤ 4 years of schooling (p < 0.001) or a family income of 3-10 times the national minimum wage. Physician-diagnosed asthma was more common among obese individuals than among those who were overweight and those of normal weight (16.1%, 9.9%, and 8.0%, respectively; p = 0.04), as were dyspnea (35.5%, 22.5%, and 17.9%, respectively; p < 0.001) and wheezing in the last year (25.6%, 11.9%, and 14.6%, respectively; p < 0.001). These results were independent of patient smoking status. In addition, obese individuals were three times more likely to report physician-diagnosed asthma than were those of normal weight (p = 0.005). Conclusions: A report of physician-diagnosed asthma showed a significant association with being ≥ 40 years of age and with having a BMI ≥ 30 kg/m2. Being obese tripled the chance of physician-diagnosed asthma.

RESUMO Objetivo: Estimar a prevalência de sintomas respiratórios e asma de acordo com o índice de massa corpórea (IMC) em indivíduos com idade ≥ 40 anos e avaliar os fatores associados ao relato de diagnóstico médico de asma. Métodos: Estudo transversal de base populacional realizado no município de Florianópolis (SC), com coleta domiciliar de dados e processo de amostragem probabilístico. Foram coletadas informações demográficas, assim como sobre relato de diagnóstico médico de asma, sintomas respiratórios, medicações em uso e comorbidades. Também foram realizadas medidas antropométricas e espirometria pré- e pós-broncodilatador. O IMC foi categorizado em normal (IMC < 25 kg/m2), sobrepeso (25 kg/m2 ≥ IMC < 30 kg/m2) e obesidade (IMC ≥ 30 kg/m2). Resultados: Foram avaliados 1.026 indivíduos, 274 (26,7%) com IMC normal, 436 (42,5%) com sobrepeso e 316 (30,8%) obesos. A prevalência de diagnóstico médico de asma foi de 11,0%. A prevalência de obesidade foi maior em mulheres (p = 0,03) e em entrevistados com escolaridade < 4 anos (p < 0,001) ou com renda familiar entre 3-10 salários mínimos. Obesos, quando comparados com aqueles com sobrepeso e peso normal, relataram mais frequentemente diagnóstico médico de asma (16,1%, 9,9% e 8,0%, respectivamente; p = 0,04), dispneia (35,5%, 22,5% e 17,9%, respectivamente; p < 0,001) e sibilos no último ano (25,6%, 11,9% e 14,6%, respectivamente; p < 0,001). Esses resultados foram independentes do status tabágico. Além disso, obesos tinham uma chance três vezes maior de relato de diagnóstico médico de asma do que não obesos (p = 0,005). Conclusões: Houve associação significativa entre o relato de diagnóstico médico de asma em indivíduos com idade ≥ 40 anos e IMC ≥ 30 kg/m2. Ser obeso triplicou a chance de diagnóstico médico de asma.

Relationship of fatigue with depressive symptoms and level of physical activity in women with breast cancer diagnosis / Relação da fadiga com sintomas depressivos e nível de atividade física em mulheres com diagnóstico do câncer de mama

Abstract Breast cancer is the most frequent in women, resulting in fatigue and depressive symptoms as consequence of treatment, but physical activity can help in this process. The aim of this study was to investigate the relationship between fatigue, depressive symptoms and practice of physical activity of women with breast cancer during treatment or after cancer treatment. This is a cross-sectional study with 179 women (56.89 ± 9.4 years) from the Oncology Research Center - CEPON, using questionnaire on general and clinical information, fatigue (Piper Fatigue Scale) depressive symptoms (Beck Depression Inventory) and physical activity (IPAQ - short version). Women with moderate to severe fatigue underwent physiotherapy (p = 0.001) and women with no fatigue had minimum depressive symptoms (p ?0.001). Level of physical activity was not associated with fatigue, with most women being insufficiently active and women with mild fatigue had longer walking time than those without fatigue (p = 0.049). Women with depressive symptoms were almost three times more likely of having mild to severe fatigue and those who underwent physiotherapy were twice as likely of having mild to severe fatigue. Women with fatigue had greater presence of depressive symptoms. Professionals working in the field of oncology should recommend the practice of physical activity in order to minimize the side effects of treatment and observe depressive symptoms and fatigue in these women.

Resumo O câncer de mama é o mais frequente nas mulheres, tendo como consequências do tratamento a fadiga e sintomas depressivos, no entanto a atividade física pode auxiliar neste processo. Objetivou-se investigar a relação entre fadiga, sintomas depressivos e prática de atividade física de mulheres com câncer de mama em fase de tratamento ou pós tratamento oncológico. Estudo transversal com 179 mulheres (56,89 ± 9,4 anos) do Centro de Pesquisas Oncológicas - CEPON, utilizando-se um questionário sobre informações gerais e clínicas, fadiga (Escala de Fadiga de Piper), sintomas depressivos (Inventário de Depressão de Beck) e atividade física (IPAQ - versão curta). As mulheres com fadiga moderada a intensa realizavam fisioterapia (p=0,001) e as mulheres com ausência de fadiga apresentaram sintomas depressivos mínimos (p ?0,001). O nível de atividade física não se associou com a fadiga, sendo que a maioria das mulheres era insuficientemente ativa e as mulheres com fadiga leve apresentaram um tempo de caminhada maior do que aquelas com ausência de fadiga (p=0,049). Mulheres com presença de sintomas depressivos apresentaram quase três vezes mais chance de apresentar fadiga leve a intensa e aquelas que realizavam fisioterapia apresentaram duas vezes mais chance de apresentar fadiga leve a intensa. Mulheres com fadiga apresentaram maior presença de sintomas depressivos. Os profissionais que atuam na área da saúde oncológica devem recomendar a prática de atividade física a fim de minimizar os efeitos colaterais do tratamento, e prestar atenção aos sinais de sintomas depressivos e fadiga nestas mulheres.