The PPI3D web server for searching, analyzing and modeling protein-protein interactions in the context of 3D structures.

Summary: The PPI3D web server is focused on searching and analyzing the structural data on protein-protein interactions. Reducing the data redundancy by clustering and analyzing the properties of interaction interfaces using Voronoi tessellation makes this software a highly effective tool for addressing different questions related to protein interactions. Availability and Implementation: The server is freely accessible at http://bioinformatics.lt/software/ppi3d/ . Contact: ceslovas.venclovas@bti.vu.lt. Supplementary information: Supplementary data are available at Bioinformatics online.