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J Expo Sci Environ Epidemiol ; 23(2): 137-44, 2013 Mar.
Artículo en Inglés | MEDLINE | ID: mdl-22805988

RESUMEN

A comprehensive search of studies describing bisphenol A (BPA) concentrations in drinking water and source waters (i.e., surface water and groundwater) was conducted to evaluate the relevance of drinking water as a source of human exposure and risk. Data from 65 papers were evaluated from North America (31), Europe (17), and Asia (17). The fraction of drinking water measurements reported as less than the detection limit is high; 95%, 48%, and 41%, for North America, Europe, and Asia, respectively. The maximum quantified (in excess of the detection limit) BPA concentrations from North America, Europe, and Asia are 0.099 µg/l, 0.014 µg/l, and 0.317 µg/l. The highest quantified median and 95th percentile concentrations of BPA in Asian drinking water are 0.026 µg/l and 0.19 µg/l, while high detection limits restricted the determination of representative median and 95th percentile concentrations in North America and Europe. BPA in drinking water represents a minor component of overall human exposure, and compared with the lowest available oral toxicity benchmark of 16 µg/kg-bw/day (includes an uncertainty factor of 300) gives margins of safety >1100. Human biomonitoring data indicate that ingestion of drinking water represents <2.8% of the total intake of BPA.


Asunto(s)
Compuestos de Bencidrilo/toxicidad , Agua Potable , Exposición a Riesgos Ambientales , Fenoles/toxicidad , Contaminantes Químicos del Agua/toxicidad , Compuestos de Bencidrilo/análisis , Monitoreo del Ambiente , Humanos , Límite de Detección , Fenoles/análisis , Contaminantes Químicos del Agua/análisis
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