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1.
Vopr Onkol ; 44(2): 164-6, 1998.
Artículo en Ruso | MEDLINE | ID: mdl-9615819

RESUMEN

A relationship between cellular immunity and general adaptation syndrome in the course of CAM polychemotherapy has been investigated. The results point to a lack of lymphopenia, lower levels of T-suppressors and higher instability of immunological indices in patients showing increased activation reaction and maximum antitumor resistance during cytostatic therapy, unlike in those in stress. This opens an opportunity for correction.


Asunto(s)
Protocolos de Quimioterapia Combinada Antineoplásica/inmunología , Neoplasias Pulmonares/tratamiento farmacológico , Neoplasias Pulmonares/inmunología , Linfocitos/efectos de los fármacos , Adulto , Anciano , Protocolos de Quimioterapia Combinada Antineoplásica/uso terapéutico , Ciclofosfamida/inmunología , Doxorrubicina/inmunología , Femenino , Humanos , Masculino , Metotrexato/inmunología , Persona de Mediana Edad , Linfocitos T/efectos de los fármacos
2.
Khirurgiia (Mosk) ; (1): 41-4, 1997.
Artículo en Ruso | MEDLINE | ID: mdl-9121046

RESUMEN

Inflammatory complications in the abdominal cavity are the most frequent complications after operations on the liver. Immunological studies were conducted in 71 patients with local lesions of the liver who had undergone various surgical interventions. Cellular and humoral immunity factors were studied. The absolute and percentage content of T- and B-lymphocytes and the level of the main three classes of immunoglobulins-A, M and G were determined. The authors noted a definite correlation between the degree of disturbance of the immune system and preoperative complications, preoperative complications of the principal disease (purulent complications--suppuration of the cavity of disintegration of the alveococcus, abscesses of the liver), functional condition of the liver, and postoperative purulent complications. The treatment of inflammatory complications in the postoperative period (suppuration of residual cavities after resection of the liver and echinococcotomy, subdiaphragmatic and subhepatic abscesses) was more effective in patients with mild changes in immunological parameters.


Asunto(s)
Infecciones Bacterianas/epidemiología , Hepatopatías/cirugía , Peritonitis/epidemiología , Complicaciones Posoperatorias , Adolescente , Adulto , Infecciones Bacterianas/complicaciones , Infecciones Bacterianas/inmunología , Femenino , Humanos , Inmunidad/inmunología , Incidencia , Hepatopatías/complicaciones , Masculino , Persona de Mediana Edad , Peritonitis/etiología , Peritonitis/inmunología
3.
Vopr Onkol ; 37(7-8): 800-5, 1991.
Artículo en Ruso | MEDLINE | ID: mdl-1842632

RESUMEN

T-lymphocyte subpopulation profile in peripheral blood of gastric cancer patients proved abnormal. The disbalance became more apparent with progression of disease. A decrease in T gamma-lymphocyte level was observed after radical surgery. T gamma- and T mu- lymphocyte levels proved significantly altered following combined treatment including surgery and chemotherapy with ftorafur or pyrogenal immunotherapy.


Asunto(s)
Adenocarcinoma/sangre , Neoplasias Gástricas/sangre , Subgrupos de Linfocitos T , Adenocarcinoma/tratamiento farmacológico , Adenocarcinoma/cirugía , Terapia Combinada , Humanos , Lipopolisacáridos/uso terapéutico , Pirógenos/uso terapéutico , Neoplasias Gástricas/tratamiento farmacológico , Neoplasias Gástricas/cirugía , Tegafur/uso terapéutico
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