Your browser doesn't support javascript.
loading
Mostrar: 20 | 50 | 100
Resultados 1 - 20 de 26
Filtrar
Más filtros











Base de datos
Intervalo de año de publicación
1.
Ter Arkh ; 80(6): 24-9, 2008.
Artículo en Ruso | MEDLINE | ID: mdl-18655471

RESUMEN

AIM: To find out correlations between severity of sclerotic affection of the glomeruli, tubules, interstitium, vessels and development of anemia in patients with glomerulopathy. MATERIAL AND METHODS: Assay of global and segmentary sclerosis, semiquantitative morphometry of severity of atrophic tubular changes, diffuse interstitial fibrosis, vascular changes (arteriolohyalinosis, elastofibrosis and perivascular sclerosis) were made in parallel with analysis of clinical laboratory data in 276 cases of chronic primary glomerulopathy with morphologically verified diagnosis by vital renal biopsy. RESULTS: Hemoglobin concentration and advance of anemia correlate negatively with severity of diffuse interstitial fibrosis and atrophic tubular alterations. However, no correlation was found between onset of anemia, severity of global and segmental glomerular sclerosis, the presence of vascular changes in the form of arteriolar hyalynosis, elastofibrosis of small arteries and perivascular sclerosis. CONCLUSION: The findings suggest that development of anemia in patients with primary glomerulopathy may be the result of structural-functional disturbances in tubular epithelium and renal stroma.


Asunto(s)
Anemia/etiología , Autoanticuerpos/inmunología , Glomerulonefritis/patología , Hemoglobinas/metabolismo , Glomérulos Renales/patología , Adolescente , Adulto , Anciano , Anemia/sangre , Anemia/patología , Biopsia , Progresión de la Enfermedad , Femenino , Estudios de Seguimiento , Glomerulonefritis/complicaciones , Glomerulonefritis/inmunología , Humanos , Masculino , Persona de Mediana Edad , Pronóstico , Estudios Retrospectivos , Índice de Severidad de la Enfermedad
SELECCIÓN DE REFERENCIAS
DETALLE DE LA BÚSQUEDA