RESUMEN
CASE REPORT: The effect of a somatostatin analogue in a patient with Graves' ophthalmopathy is presented, including data on the dose requirements and the results of therapy. DISCUSSION: There are few effective options for the management of Graves' ophthalmopathy, a cell-mediated immune co-morbidity of thyroid disease. Somatostatin analogues inhibit lymphocyte proliferation and activation, and accumulate in the orbital tissue during the active ophthalmopathy. Because of this, such therapy is able to inactivate the ophthalmopathy without complications occurring.
Asunto(s)
Oftalmopatía de Graves/tratamiento farmacológico , Péptidos Cíclicos/uso terapéutico , Somatostatina/análogos & derivados , Adulto , Humanos , Masculino , Somatostatina/uso terapéuticoRESUMEN
No disponible
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Humanos , Recurrencia , Antitiroideos , Carbimazol , Enfermedad de GravesRESUMEN
No disponible
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Persona de Mediana Edad , Adulto , Anciano , Masculino , Femenino , Humanos , Antitiroideos , Recurrencia , Pronóstico , Estudios Retrospectivos , Enfermedad de GravesRESUMEN
No disponible
No disponible
Asunto(s)
Adulto , Masculino , Humanos , Tirotropina , Octreótido , Antineoplásicos Hormonales , Adenoma , Neoplasias HipofisariasRESUMEN
Leukemia is an uncommon complication of exposure to radioiodine (131I), used in treatment of thyroid cancer, because low doses are now used. We report two cases of acute myelogenous leukemia developed after the treatment of a thyroid carcinoma with a small dose of 131I.
Asunto(s)
Carcinoma Papilar/radioterapia , Radioisótopos de Yodo/efectos adversos , Leucemia Mieloide Aguda/etiología , Leucemia Promielocítica Aguda/etiología , Leucemia Inducida por Radiación/etiología , Neoplasias Primarias Secundarias/etiología , Neoplasias de la Tiroides/radioterapia , Adulto , Femenino , Humanos , Radioisótopos de Yodo/administración & dosificaciónAsunto(s)
Anemia Refractaria/complicaciones , Diabetes Insípida/complicaciones , Anciano , Humanos , MasculinoRESUMEN
The surgical treatment of hypophyseal tumors has improved from external approach (transcranial-subtemporal) to the trans-septo-transphenoidal approach. Since the last thirty years this way to access has been increasingly used, because it provides an excellent exposure, little bleeding, is rapidly and easily performed with less morbi-morality and has smoother postoperative period. A retrospective study of 16 patients whose hypophyseal tumors were treated surgically using the trans-septo-sphenoidal transnasal (maxillary-premaxillary) approach is presented. All these patients were seen in the E.N.T. Department of Alicante's General University Hospital, between January 1990 and June 1993. The trans-septo-sphenoidal transnasal via avoids some of the problems of the sublabial trans-sphenoidal procedure; namely longer operating time, oral contamination of the surgical field, subsequence difficulties due to the lack of sensibility and discomfort of the upper jax area and postoperative alterations in the projection of the septal-columelar tip.