Ozone Concentration Levels in Urban Environments-Upper Silesia Region Case Study.

Although ozone (O3) plays a crucial role in screening the Earth's surface and lower atmosphere layers from the ultraviolet radiation, troposphere ozone is proven to have negative health effects on the human body and is one of the greenhouse gases. The objective of this study was to perform a measurement-based assessment for determining whether the concentration of ozone is within admissible limits, or exceeded, in Silesia Province and does not pose a threat to the local population. The data provided by the Voivodship Inspectorate for Environmental Protection in Katowice were used in the analysis. The received data constitute the result of 8-h measurements of concentrations of ozone at selected air monitoring stations of the Silesian province. The locations of three monitoring stations were found to be useful for the aim of this research; one site is situated in a rural background area; another one is located in a medium-sized city and the Katowice station is representative for an urban background situation. We used cluster analysis, weighted pair group method using arithmetic averages (WPGMA) and Chebyshev distances to test the hypothesis and compare empirical distributions in the general population. The alarm level has not been exceeded in indicated measurements stations in Silesian Voivodship in the period 2015-2017 (averaging time 1 h: 240 µg/m3 for 3 h). The target level was exceeded in 2015 at all three measurements stations and in the following years at one station (in Zloty Potok, 2016, and in Katowice, 2017). Each year, the largest number of exceedances occurred in August. The results clearly indicate a lack of hazards for the general population's health in terms of increased concentrations of ozone in the city centers and outside. The results confirm that environmental conditions (i.e., landform, the area surrounding monitoring station) have a significant influence on the ozone level.

Characteristics of air quality and sources affecting high levels of PM10 and PM2.5 in Poland, Upper Silesia urban area.

The reports concerning air quality published by WHO and EEA showed that 33 out of 50 cities with highest concentration of particulate matter (PM)2.5 in UE are located in Poland. Various investigations identify main health outcomes to be consistently related to PM10 and PM2.5. Increased concentration of PM is responsible for 47.3 thousands of premature deaths every year in Poland. The objective of this study was the measurement-based assessment for determining whether the concentrations of PM10 and PM2.5 are within admissible limits or exceeded in Silesia Province. The data provided by the Voivodship Inspectorate for Environmental Protection in Katowice was used in the analysis. The measurements were made in years 2009-2016 for PM2.5 and 2014-2017 for PM10 in three measurement stations: two in Katowice (capital of Silesia Province) and one in Zory. The increase in the number of excessive levels of average daily PM10 concentration in year 2017 were observed in all three measurement stations, both for the acceptable level, information and alarm level, with lack or singular excessive levels in the previous years. The increase in average annual PM2.5 concentrations in year 2016 was also observed, as compared to the previous year in all three measurement stations. The highest pollution is observed in winter. The main cause of exceeded acceptable PM concentrations in Poland is household heating systems, boilers and furnaces burnt with coal or wood, and chimneys. In Silesian Province, the air quality is poor and has deteriorated over the last year.

Influence of etanercept on leptin and ghrelin secretion in children with juvenile idiopathic arthritis.

Objective To assess possible changes in leptin and ghrelin secretion due to etanercept in juvenile idiopathic arthritis (JIA). Methods 50 patients with JIA and 16 age-matched controls were enrolled into this prospective, cross-sectional study. Serum leptin, total and acyl ghrelin were measured in addition to white blood cell (WBC) and lymphocyte counts. Results 25 patients received etanercept and 25 conventional therapies (including methotrexate) for JIA. There was no difference between treatment and control groups in leptin or ghrelin levels and no evidence of a relationship between leptin and ghrelin in patients with JIA. In all children with JIA there was a correlation between leptin and body mass index (BMI). However, compared with children in the conventional treatment group, children in the etanercept group showed a positive correlation between total ghrelin and BMI and those with a low BMI showed a negative correlation between acyl ghrelin and BMI. Conclusion No differences in leptin and ghrelin concentrations were found when patients with JIA and controls were compared or when patients who received etanercept were compared with those who received conventional treatment for JIA.

Leptin concentration in children with juvenile idiopathic arthritis.

INTRODUCTION: Leptin regulates the organism's immune response. Juvenile idiopathic arthritis (JIA) is a chronic joint disease in children, leading to chronic changes in motor organs. MATERIAL AND METHODS: In children with JIA (n = 42) and healthy subjects (n = 28), leptin concentration (LEP), body mass index (BMI), haematocrit (HTC), haemoglobin (HB), morphotic elements (WBC,LYMPH), erythrocyte sedimentation rate (ESR), and ANA Hep-2 antibodies were analysed. JIA group was divided into: children with a longer (51-148 months) (IA) n = 22 and a shorter disease period (2-18 months) (IB) n = 20. RESULTS: Only 58.3% of the IA and 50% of the IB group had ANA Hep-2 confirmed. The ill children had higher and more diversified LYMPH and ESR levels compared to the healthy children. The highest LEP for the IA group was 37.5 ng/cm3, (Me 5.85), for IB - 40.10 ng/cm3, (Me 2.46) as compared to the IC - 3.74 ng/cm3 (Me 2.85), respectively. The average BMI value for the IA group was 16.61 kg/m2, for IC it was 18.91 kg/m2, and the median for IB was 15.89 kg/m2. Children with BMI values < 23 kg/m2 from the IA and IB group had a reduction in LEP as compared to control group (p = 0.04). The relationship between the illness and LEP diversification per BMI unit was found in both groups. Children with a shorter illness period had higher LEP differentiation per BMI unit compared to the healthy children. CONCLUSIONS: Children with juvenile idiopathic arthritis with BMI < 23 kg/m2 had lower leptin concentrations than healthy subjects. Ill children with a shorter-term disease had a higher diversification of leptin concentration per BMI unit as compared to healthy controls.

Change of the nutritional habits and anthropometric measurements of type 2 diabetic patients - advantages of the nutritional education carried out.

BACKGROUND: Diabetes is one of many diseases in which prevention and treatment are essentially based on proper nutrition. Nutritional education should be a constant, integral and indispensable part of the therapeutic procedure in diabetes. OBJECTIVES: The aim of the study was an estimation of the nutritional habits of patients with type 2 diabetes before and after individual nutritional education and the answers to the question what influence this education had on the change of nutritional habits and the change of the anthropometric measurements of the patients. MATERIAL AND METHODS: 148 patients of diabetes outpatient clinics participated in our study, which contained, among others, anthropometric measurements and carrying out a questionnaire that tested dietary habits. An individual nutrition plan was established and the individual dietary education of the patients was carried out on the basis of the gathered data. The nutritional habits and the anthropometric measurements were verified again three months after the education. RESULTS: The analysis of the results received revealed an occurrence of the differences between the incidence of proper nutritional habits and middle-values of body weight and waist size in the period before and after education. Before the education, an enormous amount of improper nutritional habits were found and the values of body weight and waist size were higher, while after the education the improvement of habits and a reduction in body weight and waist size were observed. CONCLUSIONS: The results of our study carried out before the education revealed the occurrence of many unfavorable nutritional habits. As a result of the education, nutritional habits improved, which were simultaneously reflected in an improvement of the anthropometric parameters. The results of the studies carried out proved the efficiency and profitable influence of dietary education on changes to the nutritional habits of respondents).