Co-administration of curcumin and polyamines in high-fat diet induced obese rats: Assessment of changes in serum polyamine levels and some tissue parameters.

Obesity is a non-communicable chronic disease that continues to increase around the world. Recently, it has been shown that curcumin positively affects lipid, energy metabolism, and body weight change. Moreover, polyamines are aliphatic polycations, which can be found in all mammalian cells and foods and have been shown to prevent obesity through many different mechanisms. However, whether the co-administration of curcumin and polyamines has synergistic effects has yet to be clarified. Our study aimed to examine the effects of curcumin and polyamines on obesity and to assess the changes in serum polyamine levels and tissue parameters. 28 Sprague-Dawley male rats were fed a high-fat diet for 10 weeks to develop obesity, and then they were randomly divided into 4 groups as the control group (CONT), curcumin group (CUR), polyamine group (POL), curcumin and polyamine group (CUR+POL) and supplements were administered for 6 weeks. As a result, the lowest feed consumption in rats was recorded in the CUR+POL group, and the group with the lowest weight after supplements was the POL group, then the CUR+POL, CONT, and CUR groups, respectively. N-acetyl putrescine and GABA levels increased significantly after obesity development. The total histopathological score in fat, liver, and kidney tissues increased significantly in the CONT group. In the CUR+POL group, damage to the tissues was in the direction of recovery compared to the other groups, and the expression of NF-κB was significantly low. These results suggest that combined curcumin and polyamines may have protective effects.

Food addiction among university students: The effect of mindful eating.

Recent evidence indicated that lifestyle modifications, especially mindful eating, might be effective interventions for treating food addiction (FA). Mindful eating practices have been considered to regulate emotional eating, which is one predictor of FA along with automatic eating behaviors, including emotional, impulsive, and habitual eating. Thus, this cross-sectional study aimed to determine the effect of mindful eating on FA of university students. The research team collected the data with 2133 undergraduate students. The Mindful Eating Questionnaire examined the mindfulness status of the students, and the FA diagnosed by using the YALE Food Addiction Scale. 56.9% of participants were women, with a mean age of 21.5 ± 2.2 and a mean body mass index (BMI) of 22.5 ± 3.8 kg/m2. Although no significant differences were observed regarding sex (p > .05), the FA prevalence among men (16.1%) was higher than women. The overall prevalence of FA was 15.3%, which was 1.5 units higher among those with BMI ≥25 kg/m2. Also, FA diagnosis was significantly more prevalent among smokers and ex-smokers (p < .01). In addition, participants diagnosed with FA had a significantly lower mean mindful eating score (p < .001). Furthermore, those with lower mindfulness levels had a 4.96 higher risk of being food addicted (p < .000). Those with FA diagnosis had significantly lower scores regarding subscales of "disinhibition," "emotional eating," "control of eating," "mindfulness," and "interference" (p < .001). Consequently, it should be highlighted that determining the level of individuals' mindful eating may have remarkable and cumulative impacts on both obesity and FA in the long term. Thus, increasing mindful eating may be suggested as an essential strategy to control FA among young individuals.

Weight bias among dietitians: does the weight status of the patients change the dietary approaches? / Viés de peso entre os nutricionistas: o status do peso dos pacientes altera as abordagens dietéticas?

ABSTRACT Objective Since obesity is a multifactorial disease, some health professionals may esteem that weight control is a matter of personal willpower and stigmatize individuals. These weight-based attitudes seem quite common even among dietitians. This study aimed to determine whether the level of weight bias affects the dietary approaches of the dietitians. Methods Two hypothetical cases with obese and normal weight vignettes were created to be evaluated, and the explicit weight bias was assessed by the fat phobia scale among 99 dietitians via an online questionnaire. Results The majority of the dietitians demonstrated mild or moderate levels of weight bias (59.6% and 32.3%, respectively). The obese vignette had the highest agreement for nearly all adjectives and was perceived as having poorer diet quality, general health status, and insufficient physical activity level. Conclusion Overall, as weight bias is a concerning issue among most dietitians, necessary steps are required for the reduction of prejudice and thus protect the patients from stigmatizing attitudes.

RESUMO Objetivo Visto que a obesidade é uma doença multifatorial, alguns profissionais de saúde podem defender que o controle de peso é uma questão de força de vontade pessoal e estigmatizam os indivíduos. Essas atitudes baseadas no peso parecem bastante comuns mesmo entre os nutricionistas. Este estudo teve como objetivo determinar se o nível de viés de peso afeta as abordagens dietéticas dos nutricionistas. Métodos Dois casos hipotéticos com vinhetas de obesidade e peso normal foram criados para serem avaliados e o viés de peso explícito foi avaliado pela escala de fobia de gordura Fat Phobia Scale entre 99 nutricionistas por meio de um questionário online. Resultados A maioria dos nutricionistas demonstrou níveis leves ou moderados de viés de peso (59,6% e 32,3%, respectivamente). A vinheta de obesidade teve a maior concordância pela maioria e foi percebida como tendo a pior qualidade da dieta, o pior estado geral de saúde, e níveis de atividade física insuficientes. Conclusão Em suma, sendo esta uma questão que preocupa a maior parte dos nutricionistas e um problema que continua a afetar tantas pessoas, é urgente a criação de medidas que permitam diminuir o preconceito e proteger os pacientes de atitudes estigmatizantes.

The association of fat preference with eating behavior and sex: Turkish version of the Fat Preference Questionnaire©.

The fat content of food may play a role in food preferences. Increased fat intake has a role in elevated body weight. Firstly, we aimed to establish the Turkish version of the Fat Preference Questionnaire© and secondly to evaluate the relevant factors with dietary fat preference including body mass index (BMI); sex; and subscales of the Three-Factor Eating Questionnaire (TFEQ). The study was conducted with 261 participants among the academic staff of Yeditepe University. The Fat Preference Questionnaire© and TFEQ were applied. After the validity and reliability of the Turkish version of the Fat Preference Questionnaire©, Pearson's correlation coefficients were calculated to reveal the relationship between the scores of the Fat Preference Questionnaire©, BMI, and the four subscales of TFEQ. Weakly or moderately correlated variables were selected to perform two sets of hierarchical regression analyses. Turkish version of the Fat Preference Questionnaire© had statistically acceptable validity and reliability. Fat preference did not correlate with BMI (p > .05). Women showed a lower preference for high-fat foods and a higher dietary fat restriction (p < .05). The two subscales of TFEQ, the Disinhibition of Eating Control and the Susceptibility to Hunger, contributed to explain the variances in fat preference and dietary fat restriction (ΔR 2 = .04, p < .05). Fat preference correlates with Disinhibition of Eating Control and Susceptibility to Hunger, while fat restriction correlates only with Disinhibition of Eating Control although none correlates with BMI. Turkish version of the Fat Preference Questionnaire© is a valid instrument for further studies.