Can we improve the diagnosis of rupture of membranes? The value of insulin-like growth factor binding protein-1.

Our objective was to assess the value of insulin-like growth factor binding protein-1 (IGFBP-1) and other tests for the diagnosis of rupture of the membranes (ROM). We included 49 women with suspected ROM. The gold standard for membranes status was defined based on clinical examination, ultrasonography, tests results (except IGFBP-1) and labour information. Sensitivity, specificity, positive predictive value and negative predictive value of each test were as follows, respectively: IGFBP-1 (86, 74, 73 and 87%); bromothymol (64, 100, 100 and 77%); fern test (62, 96, 93 and 75%) and ultrasonography (19, 100, 100 and 61%). The detection of IGFBP-1 in vaginal secretions has high sensitivity for the diagnosis of ROM.

Sonographic detection of fluid collections and postoperative morbidity following Cesarean section and hysterectomy.

OBJECTIVES: To evaluate the clinical significance of sonographically detected fluid collections following Cesarean section and hysterectomy, and to identify risk factors associated with their formation. METHODS: This was a prospective study including 280 women, 145 of whom had undergone a Cesarean section and 135 of whom had undergone abdominal or vaginal hysterectomy. Ultrasound examinations were carried out on all women on day 4 after surgery to assess the presence of abdominal wall or pelvic fluid collections. The sonographers were unaware of the clinical course before the examination and were not involved in any clinical decision-making. Ultrasound findings were correlated with clinical data and postoperative morbidity. RESULTS: A fluid collection was found in 69 (48%) women after Cesarean section, and in 59 (44%) women who had undergone hysterectomy. No risk factors for the development of fluid collections after Cesarean section or hysterectomy were identified. The risk of developing febrile morbidity was not related to the presence, location or size of fluid collections. CONCLUSIONS: Postoperative fluid collections are common after Cesarean section and hysterectomy. As fluid collections detected by sonography were not associated with postoperative morbidity, this finding is unlikely to be useful in the workup for postoperative fever.

[Pregnancy and scuba diving: what precautions?]. / Grossesse et plongée sous-marine: quelles précautions?

Scuba diving is a leisure activity increasingly popular amongst women. Many women are concerned about the risks associated with diving and a known or planned pregnancy. In order to advise these young women, we have reviewed the literature concerning women and diving as well as animal studies on the subject. The different international federations and the Undersea and Hyperbaric Medical Society advise against scuba diving for pregnant women or those planning a pregnancy, but no randomized trials or trials provide a solid scientific basis. The fetal circulation is characterized by the exclusion of the pulmonary circulation by 2 right to left shunts. As the lung appears to act as a filter against the progression of micro-bubbles to the main circulation, the fetus may be therefore particularly exposed to gas emboli. However, the placenta could play this role in certain animal species. Nitrox diving appears to be particularly promising, but studies on the subject are still insufficient to recommend it for pregnant women.

[Closed trauma of the pancreas--diagnostic approach]. / Traumatismes fermés du pancréas--démarche diagnostique.

OBJECTIVE: To review patients who presented lesions of the pancreas following blunt abdominal trauma, in order to determine which elements contributed to or on the contrary delayed the diagnosis. Construction of a diagnostic procedure which could be followed in order to maximize the rapidity and efficency of treatment. DESIGN: Retrospective study. PATIENTS AND METHOD: Patients from 1985 to 1997 having suffered blunt trauma were studied. The lesions of the pancreas were classified according to Lucas. The grounds for indication and the information that the echography, the CT-Scan and the wirsungographie brought to the diagnosis was determined for each patient. Elements which delayed diagnosis were retrospectively evaluated. RESULTS: We treated 11 patients having suffered blunt abdominal trauma resulting in pancreatic damage. 7 patients were operated. Five had emergency laparotomies. Three of these were unable to reveal an existing rupture of the pancreatic duct. CONCLUSIONS: Surgical exploration is difficult and pancreatic lesions are frequently missed. The wirsungography done before or during the operation should, therefore, be more often used as a diagnostic tool.