Environmental factors influencing the spatio-temporal distribution of Carybdea marsupialis (Lineo, 1978, Cubozoa) in South-Western Mediterranean coasts.

Jellyfish blooms cause important ecological and socio-economic problems. Among jellyfish, cubozoans are infamous for their painful, sometimes deadly, stings and are a major public concern in tropical to subtropical areas; however, there is little information about the possible causes of their outbreaks. After a bloom of the cubomedusa Carybdea marsupialis (Carybdeidae) along the coast of Denia (SW Mediterranean, Spain) in 2008 with negative consequences for local tourism, the necessity to understand the ecological restrictions on medusae abundance was evident. Here we use different models (GAM and zero-inflated models) to understand the environmental and human related factors influencing the abundance and distribution of C. marsupialis along the coast of Denia. Selected variables differed among medusae size classes, showing different environmental restriction associated to the developmental stages of the species. Variables implicated with dispersion (e.g. wind and current) affected mostly small and medium size classes. Sea surface temperature, salinity and proxies of primary production (chl a, phosphates, nitrates) were related to the abundances of small and large size classes, highlighting the roles of springtime salinity changes and increased primary production that may promote and maintain high densities of this species. The increased primary (and secondary) production due to anthropogenic impact is implicated as the factor enabling high numbers of C. marsupialis to thrive. Recommendations for monitoring blooms of this species along the study area and applicable to Mediterranean Sea include focus effort in coastal waters where productivity have been enriched by anthropogenic activities.

Penfigoide ampolloso sobre cicatriz quirúrgica / Bullous pemphigoid on surgical scar

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Presentación cutánea anetodérmica de un trastorno linfoproliferativo postrasplante / Cutaneos anetodermal presentation of posttransplant lymphoproliferative disorder

Los trastornos linfoproliferativos postrasplante son un grupo heterogéneo de proliferaciones linfocitarias, generalmente de fenotipo B y con frecuencia asociadas al virus de Epstein-Barr (VEB), que ocurren durante el transcurso del tratamiento inmunosupresor postrasplante y comprometen la vida del paciente. La piel es una localización potencial de estos trastornos linfoproliferativos postrasplante, aunque son muy pocos los casos de afectación cutánea descritos hasta la fecha. Un varón de 41 años, trasplantado renal 11 años antes, y en tratamiento con ciclosporina A y prednisona, consultó por un nódulo eritematovioláceo anetodérmico de un año de evolución en la espalda, donde presentaba otras lesiones de anetodermia. Las biopsias mostraron una proliferación linfocitaria B, con restricción para cadenas kappa, positividad para LMP-1 (latent membrane protein 1 del VEB), y elastólisis peritumoral. El nódulo tumoral involucionó en un mes tras disminuir la dosis de ciclosporina A, realizándose radioterapia adicional de la región. Se presenta un nuevo caso de trastorno linfoproliferativo postrasplante cutáneo de fenotipo B y asociado al VEB, peculiar por presentar elastolisis peritumoral y lesiones de anetodermia previas (AU)