Extensive pipeline location data resource: Integrating reported incidents, past environmental loadings, and potential geohazards for integrity evaluations in the U.S. Gulf of Mexico.

The U.S. Gulf of Mexico contains a complex network of existing, decommissioned, and abandoned oil and gas pipelines, which are susceptible to a number of stressors in the natural-engineered offshore system including corrosion, environmental hazards, and human error. The age of these structures, coupled with extreme weather events increasing in intensity and occurrence from climate change, have resulted in detrimental environmental and operational impacts such as hydrocarbon release events and pipeline damage. To support the evaluation of pipeline infrastructure integrity for reusability, remediation, and risk prevention, the U.S. Gulf of Mexico Pipeline and Reported Incident Datasets were developed and published. These datasets, in addition to supporting advanced analytics, were constructed to inform regulatory, industry, and research stakeholders. They encompass more than 490 attributes relating to structural information, incident reports, environmental loading statistics, seafloor factors, and potential geohazards, all of which have been spatially, and in some cases temporally matched to more than 89,000 oil and gas pipeline locations. Attributes were acquired or derived from publicly available, credible resources, and were processed using a combination of manual efforts and customized scripts, including big data processing using supercomputing resources. The resulting datasets comprise a spatial geodatabase, tabular files, and metadata. These datasets are publicly available through the Energy Data eXchange®, a curated online data and research library and laboratory developed by the U.S. Department of Energy's National Energy Technology Laboratory. This article describes the contents of the datasets, details the methods involved in processing and curation, and suggests application of the data to inform and mitigate risk associated with offshore pipeline infrastructure in the Gulf of Mexico.

Relationship between level CPAP titration, anthropometric variables, and drug-induced sleep endoscopy DISE.

INTRODUCTION: Subjects with palatal obstruction alone vs. multilevel obstruction on DISE had better outcomes after palate surgery. We asked ourselves if the therapeutic level positive airway pressure (PAP) titration could predict the level of airway obstruction and its complexity. PURPOSE: The aim of this study was to identify possible relationships between therapeutic level of positive airway pressure initial titration and levels of collapse in drug-induced sleep endoscopy (DISE). A secondary objective was to establish the relationship the other variables and DISE. METHODS: We analyzed retrospective clinical histories between March 2020 to March 2022 of 37 patients with polysomnography or cardiorespiratory polygraphy studies and PAP initial titration who were taken to drug-induced sleep endoscopy. Sleep study data, anthropometric variables, and patterns of airway collapse during DISE were analyzed with PAP initial titration levels. RESULTS: Most of the patients with complex collapse had concentric velum collapse (p < 0.006). A significant association was found between the apnea-hypopnea index (AHI) and oropharyngeal collapse; (p < 0.0030) and finally we demonstrated relationship between neck circumference and gender with epiglottis collapse (p < 0.046), (p < 0.037), respectively. CONCLUSIONS: Our findings show a strong relationship between that complex collapses and concentric velum collapse; patients with greater oropharyngeal collapse have a higher mean AHI. Patients without epiglottic collapse have a higher mean neck circumference. An association between mean pressure initial titration and complex collapse could not be established.

Bacterial Prevalence and Antibiotic Resistance in Clinical Isolates of Diabetic Foot Ulcers in the Northeast of Tamaulipas, Mexico.

Diabetic foot ulcers (DFUs) are a serious and common problem in patients with diabetes mellitus and constitute one of the major causes of lower extremity amputation. The microbiological profile of DFUs depends on the acute or chronic character of the wound. Aerobic gram-positive cocci are the predominant organisms isolated from DFUs. Diabetic foot biopsies from patients admitted to the Angiology and Vascular Surgery Hospital of the Northeast, in Reynosa, Tamaulipas from December 2011 to April 2016 were analyzed. The samples were processed using standard microbiology techniques. Antimicrobial susceptibility testing was carried out according to the protocol established by the Clinical & Laboratory Standards Institute (CLSI). We obtained 246 bacterial isolates, based on the results of phenotypic resistance. The least effective antibiotics for gram-positive bacteria were penicillin and dicloxacillin; for gram-negative bacteria, cefalotin and penicillin were the least effective. Levofloxacin, cefalotin, and amikacin were the most effective antibiotics for gram-positive and negative bacteria, respectively. Enterobacter genus was significantly associated with muscle biopsies ( P = .011) and samples without growth were significantly associated with specimens of pyogenic origin ( P = .000). In 215 DFU samples, we found that Staphylococcus aureus was the most commonly isolated pathogen followed by Enterobacter sp. This is consistent with previous reports. Enterobacter species may play an important role in the colonization/infection of certain tissues; however, further studies are needed in this regard.

Neurodisplasia Intestinal: un caso inusual de distensión abdominal / Intestinal Neurodisplasia: an unusual case of bloating

La Neuronadisplasia Intestinal representa un grupo de distintas anomalías cuantitativas y cualitativas de los plexos mientérico y/o submucoso expresados por hipo o hiperganglionosis asociadas a inmadurez o heterotopia de las células ganglionares intestinales. Se presenta el caso de una niña de ocho años de edad que presenta clínica de constipación crónica asociada a distensión abdominal intermitente. Entre los exámenes de gabinete, la radiografía simple y ecografía abdominal muestran importante distensión de asas colónicas, tránsito intestinal con marcadores metálicos normal, manometría rectoanal con reflejo inhibitorio ausente compatible con alteración ganglionar, la histopatología transmural de recto evidencia la presencia de células nerviosas positivas para enolasa neuronal específica en plexo submucoso, algunas de aspecto inmaduro. Debido a que el tratamiento de esta entidad difiere sustancialmente de la enfermedad de Hirschprung, es fundamental considerarla dentro de los diagnósticos diferenciales.

The Neuronadisplasia Intestinal represents a group of different qualitative and quantitative abnormalities of the myenteric and / or submucosal plexus hiperganglionosis expressed by hypo- or heterotopia associated with immaturity or intestinal ganglion cells. For an eight-year-old female who presented clinical chronic constipation associated with intermittent abdominal distention develops. Among the tests cabinet, plain radiography and abdominal ultrasound showed significant colonic distension handles, intestinal transit normal metal markers, anorectal manometry with inhibitory reflex absent compatible with nodal alteration, transmural straight histopathology showed the presence of positive nerve cells para enolasa specific neuronal in submucosal plexus, some immature appearance. Because the treatment of this condition differs substantially from Hirschsprung's disease, it is essential to consider in the differential diagnosis.

El Método MODS, una Alternativa para el Diagnóstico de la Tuberculosis y la Detección de Cepas Multidrogoresistentes / The MODS Method, an Alternative for the Diagnosis of Tuberculosis and the Detection of Multidrug-Resistance Strains

En reiteradas ocasiones se ha establecido la necesidad de contar con un método rápido, sensible, específico y de bajo costo que permita realizar un diagnóstico oportuno de la Tuberculosis y la detección temprana de cepas de Mycobacterium tuberculosis multidrogaresistentes. Respondiendo a esta necesidad se ha diseñado un método capaz de distinguir entre pacientes con Tuberculosis y pacientes control sanos, además de facilitar la detección de cepas resistentes a los fármacos isoniacida y rifampicina de manera más rápida y efectiva en comparación con las pruebas consideradas como Gold Standard. En esta revisión analizaremos el método de Susceptibilidad a Fármacos mediante Observación Microscópica (MODS).

Has been repeatedly highlighted the need for a rapid, sensitive, specific and low-cost method that allows early diagnosis of Tuberculosis and multidrug-resistance strains. Responding to this need, a method has been designed, wich is able to distinguish between patients with Tuberculosis and healthy control patients, also facilítate the detection of drug-resistance strains to the drugs isoniazid and rifampin for faster and more effective way compared to the tests considered as Gold Standard. In this review we discuss the method Microscopic-Observation Drug Susceptibility (MODS).