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Bioorg Med Chem Lett
; 21(11): 3452-6, 2011 Jun 01.
Artículo
en Inglés
| MEDLINE
| ID: mdl-21515047
RESUMEN
Learnings from previous Roche p38-selective inhibitors were applied to a new fragment hit, which was optimized to a potent, exquisitely selective preclinical lead with a good pharmacokinetic profile.