[Menstrual function in adolescent girls in Tbilisi].

700 adolescent girls aged 10-17 were examined in the schools of Tbilisi (2004-2005). The average age of menarche was ascertained to 12.4 y, which does not differ from the corresponding data obtained in 1984 (12.5 y). Premature puberty and menarche was detected in one patient (0.25%), delayed puberty and menarche in 0.75%. The frequency of menstrual rhythm disorders was equal to 38.3%. Authentic increase of frequency of menstrual disorders in I phase of puberty rather than in II phase (49.4%, 20.7%, p<0.001) was detected. Oligomenorrhea was most frequent disorder of menstrual cycle (32.9%). Dysfunctional uterine bleeding was observed in 1.25% of adolescents, algomenorrhea in 18.5%. In cases of combination of menstrual cycle disturbances with clinical symptoms of androgenization, it is possible to consider presence of endocrine-reproductive disorders. High frequency of menstrual disorders, possible occurrence of endocrine and reproductive disorders and low rate of attendance for medical help (2.4%), indicates at importance of their early revealing, for timely treatment and avoiding complications.

[The frequency and character of clinical manifestations of androgenization among adolescent girls].

By clinical examination of 700 adolescent girls aged 11-17 high frequency of androgen depended manifestations, such as acne, seborrhea, hypertrichosis or their combination was detected in prepubertal and pubertal periods (4.7%, 6.8%, 2.9% and 20.6%, 5.3%, 3.0% correspondingly). Above-mentioned signs developed as a result of activation of androgens secretion by adrenal glands and ovaries, which are physiological processes during pubertal period. The combination of these signs with hirsutism and menstrual disorders may be a manifestation of endocrine- reproductive disorders. Results of our data indicate to infirmity, expediency and importance of prophylactic examination among adolescent girls. Low rate of attendance to medical care among adolescents with clinical manifestations with probable endocrine and reproductive disorders indicates to the importance of their early diagnosis during adolescence and timely initiation of the treatment.