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This study was initiated in 2004 because the prevalence of feline leukemia virus (FeLV) and feline immunodeficiency virus (FIV) infections in feral cats in San Mateo County (SMC) was not known. The cities attributed to the feral cat population presented to the Peninsula Humane Society & SPCA's Spay/Neuter Clinic and to the Shelter itself were analyzed to examine potential geographic concentrations of feral cats with positive retroviral status. Trends in FIV and FeLV status were examined in three 3-year periods (2001−2003, 2005−2007, and 2014−2016). Population trends over the 15 years of this study for feral cats admitted to the Shelter were also examined. In each study period, more female feral cats were presented to the S/N Clinic (54.06%, 57.37%, 54.89%). FIV prevalence increased from 5.52% to 6.41% (p = 0.29) from the first to third period; FeLV prevalence decreased significantly from 1.73% to 0.29% (p = 0.01). Significantly more FIV-positive males than females were identified each year and for each period (p < 0.01). The four largest SMC cities were the major source of feral cats to the Shelter, S/N Clinic, and of FIV- and FeLV-positive cats in the first two periods; in the third period, 50% of feral cats to the Shelter and of FeLV-positive cats were from these cities. Despite a 61.63% reduction in feral cat admissions to the S/N Clinic, the FIV prevalence for males remained similar and increased for females. The retrovirus prevalence suggests the need for continued testing and surveillance of FIV among SMC free-living cats.
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OBJECTIVE To determine effects of a shelter-neuter-return (SNR) program on cat admissions and health at a large municipal animal shelter in Northern California. DESIGN Retrospective cohort study. ANIMALS 117,383 cats for which data were recorded in the San Jose Animal Care Center database between January 1, 2006, and December 31, 2013. PROCEDURES Shelter records were analyzed for trends in cat demographic data, shelter intake and outcome types, and prevalence of upper respiratory infection (URI) over the 8-year period and before and after initiation of an SNR program on March 8, 2010. RESULTS Number of cats admitted to the shelter each year decreased significantly over 8 years; beginning in 2010, duration of stay decreased. Proportion of cats euthanized decreased from 66.6% (28,976/43,517) in the pre-SNR period to 34.9% (11,999/34,380) in the post-SNR period, whereas prevalence of URI increased from 5.5% to 6.8%, and median duration of shelter stay decreased from 6 to 5 days for cats < 4 months of age and from 8 to 6 days for older cats. With implementation of the SNR program and a new treatment policy for cats with URI, more cats received treatment with less medication, yielding cost savings. CONCLUSIONS AND CLINICAL RELEVANCE Initiation of the SNR program was associated with a decreased number of cats admitted to the shelter and a lower proportion euthanized. With increased resources to care for cats with URI and changes in the URI treatment protocol, fewer cats were euthanized for URI and more cats were treated at lower cost and with a briefer shelter stay.
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Bienestar del Animal/estadística & datos numéricos , Castración/veterinaria , Enfermedades de los Gatos/epidemiología , Infecciones del Sistema Respiratorio/veterinaria , Bienestar del Animal/economía , Animales , Castración/economía , Enfermedades de los Gatos/economía , Enfermedades de los Gatos/mortalidad , Enfermedades de los Gatos/prevención & control , Gatos , Estudios de Cohortes , Costos y Análisis de Costo , Eutanasia Animal/estadística & datos numéricos , Femenino , Estado de Salud , Masculino , Infecciones del Sistema Respiratorio/economía , Infecciones del Sistema Respiratorio/epidemiología , Infecciones del Sistema Respiratorio/mortalidad , Estudios Retrospectivos , Factores de Riesgo , Factores de Tiempo , Salud Urbana , Vacunación/estadística & datos numéricos , Vacunación/veterinariaRESUMEN
Fluctuations in iodine concentration in food have been suggested as one risk factor for the development of feline hyperthyroidism, an epidemic disease first described in 1979. Three international studies have examined iodine concentrations of commercial cat foods. The iodine concentration of 112 commercial cat foods from across the USA was measured, and the daily iodine intake by hypothetical 4.5 kg adult cats or 1.4 kg kittens calculated in this descriptive epidemiologic study to examine differences in feline iodine intake due to (i) geographical source of foods, (ii) packaging type, (iii) brand-to-brand variation, (iv) form of iodine supplementation, (v) types and numbers of seafood ingredients and (vi) kitten and 'therapeutic' diets. Dramatic variation among canned foods (resulting in ingestion of approximately 49-9639 µg iodine/day) suggests that the disparity in iodine concentrations may lead to development of nodular hyperplasia and, later, clinical hyperthyroidism, if cats consume diets that are at first iodine-deficient and later contain excessive iodine. Manufacturers are encouraged to ensure adequate iodine supplementation across all products and areas of the USA.
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Alimentación Animal/análisis , Gatos , Yodo/química , Fenómenos Fisiológicos Nutricionales de los Animales , Animales , Dieta/veterinaria , Estados UnidosRESUMEN
BACKGROUND: Radiation safety is an essential component in the treatment of patients with thyroid diseases by ¹³¹I. The American Thyroid Association created a task force to develop recommendations that would inform medical professionals about attainment of radiation safety for patients, family members, and the public. The task force was constituted so as to obtain advice, experience, and methods from relevant medical specialties and disciplines. METHODS: Reviews of Nuclear Regulatory Commission regulations and International Commission on Radiological Protection [corrected] recommendations formed the basic structure of the recommendations. Members of the task force contributed both ideas and methods that are used at their respective institutions to aid groups responsible for treatments and that instruct patients and caregivers in the attainment of radiation safety. There are insufficient data on long-term outcomes to create evidence-based guidelines. RESULTS: The information was used to compile delineations of radiation safety. Factors and situations that govern implementation of safety practices are cited and discussed. Examples of the development of tables to ascertain the number of hours or days (24-hour cycles) of radiation precaution appropriate for individual patients treated with ¹³¹I for hyperthyroidism and thyroid cancer have been provided. Reminders in the form of a checklist are presented to assist in assessing patients while taking into account individual circumstances that would bear on radiation safety. Information is presented to supplement the treating physician's advice to patients and caregivers on precautions to be adopted within and outside the home. CONCLUSION: Recommendations, complying with Nuclear Regulatory Commission regulations and consistent with guidelines promulgated by the National Council on Radiation Protection and Measurement (NCRP-155), can help physicians and patients maintain radiation safety after treatment with ¹³¹I of patients with thyroid diseases. Both treating physicians and patients must be informed if radiation safety, an integral part of therapy with ¹³¹I, is to be attained. Based on current regulations and understanding of radiation exposures, recommendations have been made to guide physicians and patients in safe practices after treatment with radioactive iodine.
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Radioisótopos de Yodo/uso terapéutico , Protección Radiológica/métodos , Enfermedades de la Tiroides/radioterapia , Lactancia Materna , Familia , Femenino , Agencias Gubernamentales , Humanos , Hipertiroidismo/radioterapia , Embarazo , Seguridad , Sociedades Médicas , Neoplasias de la Tiroides/radioterapia , Estados UnidosRESUMEN
OBJECTIVE: To determine the prevalence of infectious diseases of animal and zoonotic importance in cats and dogs rescued and transferred from the Gulf Coast region following Hurricane Katrina. DESIGN: Cross-sectional study. ANIMALS: 414 dogs and 56 cats rescued and transferred from the Gulf Coast region within 4 months after the hurricane. PROCEDURES: EDTA-anticoagulated blood and serum samples were tested via PCR and serologic assays for infectious diseases. RESULTS: In dogs, prevalence was highest for anti-West Nile virus (WNV) antibodies (218/390 [55.9%]), Dirofilaria immitis antigen (195/400 [48.8%]), anti-Toxoplasma gondii antibodies (92/366 [25.1%]), and hemotropic mycoplasma DNA (40/345 [11.9%]). The DNA of Bartonella spp, Ehrlichia spp, or Babesia spp or anti-canine influenza virus antibodies were identified in < 2% of dogs. In cats, prevalence was highest for antibodies against Bartonella spp and DNA of Bartonella spp combined (49/55 [89.1 %]), anti-T gondii antibodies (13/55 [23.6%]), hemotropic mycoplasma DNA (5/47 [10.6%]), anti-WNV antibodies (5/48 [10.4%]), D immitis antigen (4/50 [8.0%]), and anti-FIV antibodies (4/56 [7.1%]). A total of 308 (74.4%) dogs and 52 (92.9%) cats had evidence of previous or current vector-borne infections. CONCLUSIONS AND CLINICAL RELEVANCE: Cats and dogs rescued from the disaster region had evidence of multiple infectious diseases. The dispersal of potentially infectious animals to other regions of North America where some infections were not typically found could have contributed to new geographic ranges for these organisms or to underdiagnosis in affected animals because of a low index of suspicion in regions with low disease prevalence.
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Enfermedades de los Gatos/epidemiología , Enfermedades Transmisibles/veterinaria , Tormentas Ciclónicas , Desastres , Enfermedades de los Perros/epidemiología , Animales , Enfermedades de los Gatos/transmisión , Gatos , Enfermedades Transmisibles/epidemiología , Enfermedades Transmisibles/transmisión , Enfermedades de los Perros/transmisión , Perros , Femenino , Masculino , Prevalencia , Estados Unidos/epidemiologíaRESUMEN
BACKGROUND: There is little information about the individual safety instructions provided by healthcare professionals to patients receiving radioactive iodine (I-131) therapy for the treatment of benign and malignant thyroid disorders or about whether these instructions are consistent across medical specialties. Currently, no national guidelines exist to standardize safety instructions related to I-131 administration. Here, we examine the spectrum of I-131 safety practices in contemporary use. METHODS: Members of major societies of physicians and allied specialists who treat patients with thyroid disorders were invited to complete a 27-question online survey about safety practices related to I-131 administration. Data from questionnaires were analyzed by type of safety recommendation and grouped according to provider specialty and geographic location. RESULTS: A total of 311 endocrinologists, surgeons, nuclear medicine radiologists, and allied health professionals completed questionnaires. They indicated that patients often receive instruction from more than one treating specialist. The decision to hospitalize a patient for treatment and the length of stay were determined by the patient's social situation and the dose of I-131 administered. Starting at I-131 doses between 259 and 1073 MBq (7 and 29 mCi), over 60% of respondents advised avoiding contact with children, sexual activity, and breastfeeding, with the latter recommendation continuing beyond 48 hours after treatment. Personal hygiene, laundry, and meal preparation precautions varied across respondents. Over 90% of respondents used serum or urine testing to screen for pregnancy status. Precautions to delay parenthood were given more often to female than male patients (90% vs. 60%), with a minimum recommended delay of 6 months. About 20% of respondents considered insurance coverage as a factor in selecting outpatient versus inpatient I-131 therapy, and this consideration varied geographically. CONCLUSION: A wide variety of safety recommendations are given to patients who receive I-131. To our knowledge, this survey represents the first organized inquiry into safety practices related to I-131 administration. The diversity of responses suggests an opportunity for multispecialty collaboration in defining more uniform recommendations for patient safety instructions during and after I-131 treatment.
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Técnicos Medios en Salud , Radioisótopos de Yodo/administración & dosificación , Radioisótopos de Yodo/uso terapéutico , Pautas de la Práctica en Medicina , Administración de la Seguridad/métodos , Enfermedades de la Tiroides/radioterapia , Canadá , Recolección de Datos , Relación Dosis-Respuesta en la Radiación , Bocio/radioterapia , Humanos , Hipertiroidismo/radioterapia , México , Neoplasias de la Tiroides/radioterapia , Estados UnidosRESUMEN
UNLABELLED: ARTICLE RATIONALE: Since the late 1970s, there has been a significant increase in the prevalence of feline hyperthyroidism (FH). It is now recognized worldwide as the most common endocrinopathy of older cats, resembling toxic nodular goiter of older humans in iodine-deficient areas. The purpose of this article is to identify the potential for iodine concentrations in the diet to contribute to the etiology of FH. HISTORICAL CONTEXT: Iodine concentrations of commercial cat foods vary widely. A review of historical iodine recommendations revealed that the units of iodine supplementation changed in the 1970s. Given this change, foods minimally supplemented since the late 1970s would have been iodine deficient for most cats. PRACTICAL RELEVANCE: Iodine supplementation of commercial cat foods should be evaluated in the light of the iodine recommendations revised in 2006. Foods may remain deficient in iodine if supplemented at the minimum recommended concentration, possibly contributing to the development of FH.
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Alimentación Animal/análisis , Enfermedades de los Gatos/etiología , Suplementos Dietéticos , Hipertiroidismo/veterinaria , Yodo/administración & dosificación , Fenómenos Fisiológicos Nutricionales de los Animales , Animales , Enfermedades de los Gatos/epidemiología , Gatos , Suplementos Dietéticos/análisis , Hipertiroidismo/epidemiología , Hipertiroidismo/etiología , Yodo/efectos adversos , Necesidades Nutricionales , Factores de RiesgoRESUMEN
OBJECTIVE: To determine the proportion of dogs entering an animal shelter with protective antibody titers (PATs) for canine distemper virus (CDV) and canine parvovirus (CPV) and identify factors associated with having a PAT. DESIGN: Cross-sectional study. ANIMALS: 431 dogs admitted to an open-admission municipal animal shelter in north central Florida with a history of infectious disease outbreaks. PROCEDURES: Blood was collected from dogs on the day of admission to the shelter. Antibody titers for CDV and CPV were measured by virus neutralization and hemagglutination inhibition, respectively. Age, sex, neuter status, address of origin, source (stray or previously owned), health status (healthy or not healthy), and outcome (adoption, euthanasia, or reclaimed by owner) data were also collected. RESULTS: Overall, 64.5% (278/431) of dogs had insufficient titers for antibodies against CDV, CPV, or both. A total of 153 (35.5%) dogs had PATs for both CDV and CPV, 33 (7.7%) had PATs for CDV but not CPV, 136 (31.5%) had PATs for CPV but not CDV, and 109 (25.3%) did not have PATs for either virus. Older dogs were more likely to have PATs for CDV and CPV. Neutered dogs were more likely to have PATs for CDV. Factors not associated with having a PAT included source, health status, and type of community from which the dog originated. CONCLUSIONS AND CLINICAL RELEVANCE: Most dogs had insufficient antibody titers for CDV, CPV, or both at the time of admission to the animal shelter. Findings support current guidelines recommending vaccination of all dogs immediately upon admission to shelters, regardless of source or physical condition.
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Anticuerpos Antivirales/sangre , Virus del Moquillo Canino/inmunología , Enfermedades de los Perros/sangre , Enfermedades de los Perros/inmunología , Parvovirus Canino/inmunología , Animales , Estudios Transversales , Moquillo/sangre , Moquillo/epidemiología , Moquillo/inmunología , Enfermedades de los Perros/epidemiología , Perros , Florida/epidemiología , Vivienda para Animales , Infecciones por Parvoviridae/sangre , Infecciones por Parvoviridae/epidemiología , Infecciones por Parvoviridae/inmunologíaRESUMEN
OBJECTIVE: To determine the seroprevalences of and seroconversion rates for FeLV and FIV infection in cats treated for bite wounds and cutaneous abscesses and to evaluate compliance with recommendations to determine the retrovirus infection status of cats at acquisition and 60 days after a high-risk event. DESIGN: Prospective study. ANIMALS: 967 cats from 134 veterinary practices in 30 states. PROCEDURES: Cats with bite wounds or abscesses were evaluated by use of a point-of-care immunoassay for blood-borne FeLV antigen and FIV antibody. Veterinarians were asked to retest cats approximately 60 days later to determine whether seronegative cats had seroconverted after injury. RESULTS: The combined FeLV-FIV status of only 96 (9.9%) cats was known prior to wound treatment. At the time of treatment, 187 (19.3%) cats were seropositive for 1 or both viruses. Age (adult), sex (male), history of cutaneous wounds, and outdoor access were significantly associated with seropositivity. At 73 of 134 (54.5%) veterinary practices, retesting of cats for retrovirus infection status was recommended to owners of 478 cats. Only 64 (13.4%) cats were retested; of these, 3 of 58 (5.2%) cats that were initially seronegative for FIV antibody seroconverted. CONCLUSIONS AND CLINICAL RELEVANCE: A high proportion of cats with abscesses or bite wounds were seropositive for FeLV antigen or FIV antibody. Compliance with recommendations to test cats for retrovirus infection status at acquisition or after treatment for injury was low. The FeLV-FIV infection status of cats with potential fight wounds should be determined at time of treatment and again 60 days later.
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Enfermedades de los Gatos/virología , Virus de la Inmunodeficiencia Felina/inmunología , Virus de la Leucemia Felina/inmunología , Pautas de la Práctica en Medicina , Pruebas Serológicas/veterinaria , Medicina Veterinaria/normas , Absceso/veterinaria , Absceso/virología , Factores de Edad , Animales , Anticuerpos Antivirales/sangre , Antígenos Virales/inmunología , Enfermedades de los Gatos/diagnóstico , Gatos , Intervalos de Confianza , Femenino , Masculino , Tamizaje Masivo , Oportunidad Relativa , Guías de Práctica Clínica como Asunto , Factores Sexuales , Factores de Tiempo , Estados Unidos , Heridas y Lesiones/veterinaria , Heridas y Lesiones/virologíaRESUMEN
OBJECTIVE: To determine seroprevalence of dirofilariasis in dogs and seroprevalences of dirofilariasis, FeLV infection, and FIV infection in cats exported from the Gulf Coast region following the 2005 hurricanes. DESIGN: Seroprevalence survey. ANIMALS: 1,958 dogs and 1,289 cats exported from Louisiana, Mississippi, and Texas between August 20 and December 31, 2005. PROCEDURES: 141 animal welfare groups in 37 states and Alberta, Canada, reported results of serologic testing. Risk factors for infection, including age, sex, neuter status, breed, and state of rescue, were examined by means of univariate and multivariate logistic regression. RESULTS: Seroprevalence of dirofilariasis in dogs was 48.8%. Sexually intact dogs were 1.6 times as likely to have dirofilariasis as were neutered dogs, dogs in the ancient breed group were 2.2 times as likely and dogs in the guarding breed group were 1.7 times as likely to have dirofilariasis as were dogs in the herding breed group, and dogs from Mississippi were significantly less likely to have dirofilariasis than were dogs from Texas. Seroprevalences of dirofilariasis, FeLV infection, and FIV infection in cats were 4.0%, 2.6%, and 3.6%, respectively. Seroprevalence of FIV infection was significantly higher in adult cats than in juveniles and in males than in females. CONCLUSIONS AND CLINICAL RELEVANCE: Results suggest that dogs and cats exported from the 2005 Gulf Coast hurricane disaster area had disease rates similar to those for animals in the region prior to the hurricanes.
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Anticuerpos Antihelmínticos/sangre , Anticuerpos Antivirales/sangre , Dirofilariasis/epidemiología , Enfermedades de los Perros/epidemiología , Síndrome de Inmunodeficiencia Adquirida del Felino/epidemiología , Leucemia Felina/epidemiología , Animales , Castración/efectos adversos , Castración/veterinaria , Gatos , Dirofilaria immitis/inmunología , Perros , Femenino , Virus de la Inmunodeficiencia Felina/inmunología , Virus de la Leucemia Felina/inmunología , Louisiana/epidemiología , Masculino , Mississippi/epidemiología , Factores de Riesgo , Estudios Seroepidemiológicos , Texas/epidemiologíaRESUMEN
Perchlorate (ClO4-) has been detected in groundwater sources in numerous communities in California and other parts of the United States, raising concerns about potential impacts on health. For California communities where ClO4- was tested in 1997 and 1998, we evaluated the prevalence of primary congenital hypothyroidism (PCH) and high thyroid-stimulating hormone (TSH) levels among the 342,257 California newborns screened in 1998. We compared thyroid function results among newborns from 24 communities with average ClO4- concentrations in drinking water>5 microg/L (n=50,326) to newborns from 287 communities with average concentrations
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Percloratos/toxicidad , Pruebas de Función de la Tiroides , Glándula Tiroides/efectos de los fármacos , Abastecimiento de Agua/análisis , California , Humanos , Recién Nacido , Tamizaje Neonatal , Glándula Tiroides/fisiopatologíaRESUMEN
PURPOSE: To assess the relationship between occupational magnetic field (MF) exposure and cardiovascular disease (CVD) mortality and to determine whether smoking could confound this relationship. METHODS: Death certificate and proxy respondent information from the US 1986 and 1993 National Mortality Followback Surveys (NMFS) were used to determine whether job titles with potential occupational MF exposure were risk factors for CVD mortality and whether smoking behavior may confound the observed relationship. A qualitative MF exposure matrix was developed based on job titles and published exposure measurements. In a case-control analysis, logistic regression models, adjusting for age, sex, race, working status, level of education, and survey year, were used to examine the associations between estimated MF exposure and death from CVD. To assess the effect of adjustment for smoking, we conducted our analyses with and without including smoking-related variables in the models, and evaluated the change in CVD risk estimates. RESULTS: There was no consistent dose-response relationship between occupational MF exposure estimates and CVD mortality. Adjustment for smoking behavior did not appreciably change the observed MF exposure-CVD mortality relationship. CONCLUSIONS: Although limited by self-reported information on exposure and smoking, our results suggest that CVD mortality was not associated with MF exposure in this study, and smoking behavior was not an apparent confounder of the MF-CVD association.
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Enfermedades Cardiovasculares/mortalidad , Campos Electromagnéticos/efectos adversos , Exposición Profesional/efectos adversos , Ocupaciones , Fumar/efectos adversos , Enfermedades Cardiovasculares/etiología , Factores de Confusión Epidemiológicos , Femenino , Humanos , Modelos Logísticos , Masculino , Fumar/epidemiología , Estados Unidos/epidemiologíaRESUMEN
A placebo-controlled field trial was conducted to compare the effectiveness of intranasal (IN) vaccines containing Bordetella bronchiseptica and canine-parainfluenza virus, with (IN-BPA) or without (IN-BP) canine-adenovirus type 2, for prevention of kennel cough at a humane shelter. Dogs were examined on admission to the shelter and those without respiratory signs of disease were assigned daily, on a rotating basis, to receive one of three vaccines. We enrolled 972 healthy dogs. Dogs were monitored for up to 30 days post-vaccination for coughing and other clinical signs of respiratory disease. Thirty-three (10.7%; 95% confidence interval (CI): 7.2%, 14.2%) dogs in the IN-BP group, 36 (10.2%; CI: 7.0%, 13.4%) [corrected] dogs in the IN-BPA group, and 42 (13.5%; CI: 9.7%, 17.3%) [corrected] dogs in the IN-P group coughed spontaneously for > or = 1 day within 30 days of vaccination (P = 0.37). The IN-BP and IN-BPA vaccines were 20.7 and 24.4% effective, respectively, in reducing coughing compared with a placebo vaccine. The strongest prognostic factor for coughing (regardless of vaccine group) was the number of days spent at the shelter, with each additional day increasing the risk of coughing by 3% (95% CI: 1.01, 1.06) [corrected] The low incidence of coughing in the shelter during this study precluded observation of differences in vaccine effectiveness. No differences in vaccine-associated adverse events (coughing, sneezing, nasal or ocular discharge) were noted during the first 3 days post-administration or thereafter.
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Bronquitis/veterinaria , Enfermedades de los Perros/prevención & control , Vacunas/administración & dosificación , Adenoviridae/inmunología , Administración Intranasal , Animales , Bordetella bronchiseptica/inmunología , Bronquitis/prevención & control , Enfermedades de los Perros/patología , Perros , Femenino , Vivienda para Animales , Masculino , Virus de la Parainfluenza 1 Humana/inmunología , Resultado del Tratamiento , Vacunación/veterinariaRESUMEN
OBJECTIVE: To determine whether the increasing prevalence of feline hyperthyroidism is the result of aging of the cat population and whether consumption of canned foods at various times throughout life is associated with increased risk of hyperthyroidism. DESIGN: Retrospective and case-control studies. STUDY POPULATION: Medical records of 169,576 cats, including 3,570 cats with hyperthyroidism, evaluated at 9 veterinary school hospitals during a 20-year period, and 109 cats with hyperthyroidism (cases) and 173 cats without hyperthyroidism (controls). PROCEDURE: Age-adjusted hospital prevalence of hyperthyroidism was calculated by use of Veterinary Medical Database records. On the basis of owners' questionnaire responses, logistic regression was used to evaluate associations between consumption of canned food and development of hyperthyroidism. RESULTS: Age-specific hospital prevalence of feline hyperthyroidism increased significantly from 1978 to 1997. Overall, consumption of pop-top canned (vs dry) food at various times throughout life and each additional year of age were associated with greater risk of developing hyperthyroidism. In female cats, increased risk was associated with consumption of food packaged in pop-top cans or in combinations of pop-top and non-pop-top cans. In male cats, increased risk was associated with consumption of food packaged in pop-top cans and age. CONCLUSIONS AND CLINICAL RELEVANCE: These findings suggest that the increasing prevalence of feline hyperthyroidism is not solely the result of aging of the cat population and that canned foods may play a role.