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Pediatr Transplant ; 24(6): e13724, 2020 09.
Artículo en Inglés | MEDLINE | ID: mdl-32388917

RESUMEN

Pediatric kidney transplantation is a multidisciplinary therapy that needs special consideration and experience. In this study, we aimed to present CUCH experience; over a 10-year period, as a specialized center of kidney transplantation in children. We studied 148 transplantations performed at a single center from 2009 to 2018. Pretransplant and follow-up data were collected and graft/patient survival rates were evaluated. A total of 48 patients developed at least one rejection episode during 688 patient-years of follow-up. Infections, recurrence of original disease, and malignancy were the most important encountered medical complications (20%, 2%, and 1.4%, respectively). One-year patient survival was 94.1%, while graft and patient survival was 91.9%. Graft/patient survival at 5, 7, and 9 years was 90%, 77%, and 58%, respectively. Infections were the main cause (69%) of mortality. Death with a functioning graft and CR were the main causes of graft loss (48% and 33%, respectively). Pediatric kidney transplantation in Egypt is still a challenging yet successful experience. Rejections and infections are the most frequent complications. Short-term outcomes surpass long-term ones and graft survival rates are similar to the international standard.


Asunto(s)
Trasplante de Riñón/métodos , Pediatría/métodos , Adolescente , Biopsia , Niño , Preescolar , Egipto/epidemiología , Femenino , Estudios de Seguimiento , Rechazo de Injerto , Supervivencia de Injerto , Humanos , Terapia de Inmunosupresión , Lactante , Estimación de Kaplan-Meier , Fallo Renal Crónico/cirugía , Masculino , Periodo Perioperatorio , Recurrencia , Estudios Retrospectivos , Resultado del Tratamiento
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