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1.
Food Funct ; 11(2): 1891, 2020 Feb 26.
Artículo en Inglés | MEDLINE | ID: mdl-31990022

RESUMEN

Correction for 'Benefits of the ipowder® extraction process applied to Melissa officinalis L.: improvement of antioxidant activity and in vitro gastro-intestinal release profile of rosmarinic acid' by Valérie Bardot et al., Food Funct., 2020, DOI: 10.1039/c9fo01144g.

2.
Food Funct ; 11(1): 722-729, 2020 Jan 29.
Artículo en Inglés | MEDLINE | ID: mdl-31912082

RESUMEN

The objective of this study was to evaluate the benefits of a new extraction process, the ipowder® technology, applied to Melissa officinalis L. Compared to M. officinalis ground dry leaves, the ipowder® had a similar phytochemical fingerprint but contained twice the concentration of rosmarinic acid (by HPTLC and HPLC) and had a two-fold greater antioxidant activity (DPPH* method). In vitro digestion experiments (TIM-1 model) showed better availability of rosmarinic acid for intestinal absorption with the ipowder® than with ground dry leaves, manifested by a three-fold reduction in the quantity of ingested product needed for delivery of the same amount of rosmarinic acid into the upper gastro-intestinal tract. This study shows that the ipowder® technology preserves all the original plant compounds intact while making some active ingredients more accessible and available to exert their effects. To obtain a given effect, the amount of ipowder® extract to ingest will therefore be lower; a reduction in the daily dosage will be more convenient for the patient and will improve patient compliance with supplementation.


Asunto(s)
Antioxidantes/química , Cinamatos/química , Depsidos/química , Intestinos/efectos de los fármacos , Melissa , Extractos Vegetales/química , Estómago/efectos de los fármacos , Antioxidantes/farmacología , Cinamatos/farmacología , Depsidos/farmacología , Composición de Medicamentos , Humanos , Técnicas In Vitro , Modelos Anatómicos , Fitoterapia , Hojas de la Planta/química , Ácido Rosmarínico
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