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BMJ Case Rep ; 20182018 Feb 23.
Artículo en Inglés | MEDLINE | ID: mdl-29477994

RESUMEN

Acute endocapillary glomerulonephritis, as its name suggests, is a one-time process, which usually resolves within weeks. However, in a small percentage of patients, the disease becomes chronic. In these cases, a deregulation in the alternative complement pathway, which can be caused by mutations or autoantibodies, has been proposed as a pathophysiological mechanism. As a result, the alternative complement pathway remains active after resolution of infection. We report a patient with two episodes of acute renal failure, both times diagnosed by renal biopsy of acute endocapillary glomerulonephritis, with slow recovery after two episodes of low-serum complement C3, haematuria and proteinuria.


Asunto(s)
Complemento C3/inmunología , Glomerulonefritis/complicaciones , Glomerulonefritis/inmunología , Infecciones/complicaciones , Lesión Renal Aguda/etiología , Lesión Renal Aguda/inmunología , Lesión Renal Aguda/patología , Anciano , Biopsia , Vía Alternativa del Complemento/inmunología , Glomerulonefritis/patología , Humanos , Infecciones/inmunología , Riñón/inmunología , Riñón/patología , Masculino , Recurrencia
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