1.
Euro Surveill
; 28(28)2023 07.
Artículo
en Inglés
| MEDLINE
| ID: mdl-37440346
RESUMEN
An outbreak of Ralstonia mannitolilytica bloodstream infections occurred in four hospitals in north-eastern Italy, involving 20 haemodialysis patients with tunnelled central vascular catheter access. We identified as the outbreak source a batch of urokinase vials imported from India contaminated with R. mannitolilytica. Whole genome sequences of the clinical and urokinase strains were highly related, and only urokinase-treated patients were reported with R. mannitolilytica infections (attack rate = 34%; 95% confidence interval:â¯22.1-47.4). Discontinuation of the contaminated urokinase terminated the outbreak.