Cystadenocarcinoma of the appendix: an incidental perioperatory finding in a patient with adenocarcinoma of the ascending and sigmoid colon: case report and review of literature.

BACKGROUND: Primary adenocarcinomas of the appendix are uncommon, constituting 1% of all colorectal malignancies. Appendiceal malignancies often present atypically, thus creating diagnostic challenges. Although there are many pathology reports of primary cystadenocarcinoma of the appendix, only a limited number of cases have appeared in the radiological or surgical literature. We present a unique case of primary cystadenocarcinoma of the appendix occurring concurrently with adenocarcinoma of the colon, and overview the clinical and therapeutic difficulties posed by this rare entity. CASE PRESENTATION: A mucocele of the appendix, due to mucinous cystadenocarcinoma, was documented as an incidental perioperatory finding in a 68-year-old female. The patient was admitted due to rectal haemorrhage and underwent colonoscopy with biopsy, X-ray, abdominal ultrasonography and CT scan. Degenerated adenomatous polyp of the ascending colon and mucinous adenocarcinoma of the sigmoid colon invading the parietal peritoneum of the uterine and vagina was diagnosed. At laparoscopy, a cystic appendiceal lesion was found, without perforation. The patient underwent right hemicolectomy, sigmoidectomy and hysterectomy associated with salpingo-oophrectomy. CONCLUSIONS: Preoperative diagnosis of an underlying malignancy in a mucocele is important for patient management, but is difficult to reach by imaging studies alone. Synchronous colon cancer may occur in patients with appendiceal mucoceles. In such patients, the colon should be investigated. Surgery is the recommended method of treatment.

[Immunohistochemical study of endometrial stromal sarcoma and smooth-muscle tumors of the uterus]. / Etude immunohistochimique des sarcomes du stroma endométrial et des tumeurs musculaires lisses de l'utérus.

OBJECTIVES: Positive and differential diagnoses of mesenchymal tumors of the uterus may be sometimes problematic. The purpose of this study was to evaluate the utility of a panel of antibodies in this diagnosis. MATERIALS AND METHODS: The expression of AML, desmin, h-caldesmon and CD10 was studied in nine endometrial stromal sarcomas (SSE), two leiomyosarcomas (LMS) and 10 highly-cellular leiomyoma (HCL). RESULTS: AML positivity was found in five SSE, in all HCL and in only one LMS. Desmin expression was found in two SSE, in all HCL and LMS. H-caldesmon was negative in all SSE, positive in all HCL and in one case of LMS. CD10 was expressed in two-third of SSE. However, neither HCL nor LMS was marqued. CONCLUSION: CD10 is the most specific antibody of SSE. It seems to have the best value in the diagnosis of mesenchymal tumors in association with desmin and h-caldesmon, specific markers of smooth-muscle differentiation.

[Adenoid cystic carcinoma of the trachea]. / Carcinome adénoïde kystique de la trachée.

UNLABELLED: Cystic adenoid carcinoma of the trachea, also called cylindroma, is a rare malignant tumor accounting for 1% of all respiratory tract cancers. OBJECTIVES: To recall through two observations and a review of the literature, various epidemiologic anatomical clinical aspects, and evolutionary of cystic glandular carcinome of the respiratory tracts. We report 2 cases of cystic glandular carcinoma of the trachea. CLINICAL CASE: They were two women of 60 and 49 year old who came with a deterioration of the general status with dyspnea, dysphonia and/or dysphagia. Radiological explorations visualized, in the first case, a tumoral process of the superior half of the trachea and, in the second case, a tumoral circumferential process budding in the sub-glottic area and reaching the first rings of the trachea. The two patients had a removal of the tumour An auxiliary radiotherapy was indicated in the first case. CONCLUSION: Cystic adenoid carcinomas of the trachea are rare tumours. Their diagnosis is based on the bronchial fibroscopy associated with the biopsy. The optimal treatment is surgical associated with the radiotherapy. The palliative treatments keep a place among inoperable patients.

[Beta 2-microglobulin amyloidosis presenting as intestinal perforation in a haemodialysis patient]. / Amyloïdose de type beta2-microglobuline révélée par une perforation intestinale chez une hémodialysée chronique.

Long term haemodialysis patient is subject to several complications such as generalised amyloidosis which is the result of deposits of beta2-microglobulin not depurated by haemodialysis. Digestive location causes ischemic accidents such as ulcer, infarctus, digestive haemorrhage, pseudo-obstruction and perforation manifested by a surgical emergency. Our observation is the 6th case of intestinal perforation caused by amyloidosis deposit reported in the literature.

[Adenomatoid odontogenic tumor: two cases]. / La tumeur odontogénique adénomatoïde: deux cas.

INTRODUCTION: Adenomatoid odontogenic tumor, initially referred to as adenoameloblastoma, is a rare and benign odontogenic tumor. No recurrence has been reported after enucleation-resection. CASE REPORTS: We report two cases of adenomatoid odontogenic tumor, which illustrate the radiological and anatomic features of this tumor. They occurred in two 21 and 14 years-old teenagers who presented gingival swelling. The panoramic radiographs showed a radiolucent lesion with an impacted tooth. Enucleation-resection was performed with good outcome. DISCUSSION: The clinical, radiological and histological features of adenomatoid odontogenic tumor are distinct from those of ameloblastoma. It affects most commonly patients in the second decade of life predominantly females. This tumor is frequently misdiagnosed as other odontogenic cysts or tumors. We discuss the anatomoclinical features and the histogenesis of this rare tumor.

Lipomatous hemangiopericytoma (adipocytic variant of solitary fibrous tumor) of the orbit. A case report with review of the literature.

Hemangiopericytoma (HPC) of the orbit is a rare tumor presenting with slowly progressive proptosis, ocular motility impairment and visual loss. In 1995, a newly variant of HPC termed lipomatous hemangiopericytoma (LHPC), was described. Only two cases arising in the orbit have been previously reported. The authors describe another case of orbital LHPC and discuss the clinicopathologic features, including the immunohistochemical staining profile and ultrastructural appearance of this distinctive tumor, and briefly discuss the relationship between HPC and solitary fibrous tumor of soft tissue, a neoplasm with many clinical and pathologic similarities.

[Subcutaneous dirofilariasis due to Dirofilaria repens in Tunisia: a case involving the scrotum]. / Dirofilariose sous-cutanée à Dirofilaria repens en Tunisie: une observation à localisation scrotale.

Dirofilariasis is a rare anthroponotic disease encountered only in the old world with most cases having been reported from Italy. The dog is the reservoir of this parasite. Man is accidentally infected by mosquitoes. We report the case involving a 27-year-old man living in a rural region of northern Tunisia who presented with a subcutaneous abscess-like scrotal nodule. Microscopic examination of the surgical specimen unexpectedly revealed parasitic involvement. Morphologic examination led to diagnosis of subcutaneous dirofilariasis due to Dirofilaria repens. This case of subcutaneous dirofilariasis brings the total number of cases reported in Tunisia to 6 and is a reminder that this parasitic disease is present in our country and that its incidence is probably underestimated. The scrotum is a rare location that poses the problem of differential diagnosis with malignant tumor or can simulate a surgical emergency. Excision allows diagnosis and treatment.