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1.
Sci Rep ; 14(1): 3051, 2024 Feb 06.
Artículo en Inglés | MEDLINE | ID: mdl-38321089

RESUMEN

This paper presents a novel approach to solve the optimal power flow (OPF) problem by utilizing a modified white shark optimization (MWSO) algorithm. The MWSO algorithm incorporates the Gaussian barebones (GB) and quasi-oppositional-based learning (QOBL) strategies to improve the convergence rate and accuracy of the original WSO algorithm. To address the uncertainty associated with renewable energy sources, the IEEE 30 bus system, which consists of 30 buses, 6 thermal generators, and 41 branches, is modified by replacing three thermal generators with two wind generators and one solar PV generator. And the IEEE 57-bus system, which consists of 57 buses, 7 thermal generators, and 80 branches, is also modified by the same concept. The variability of wind and solar generation is described using the Weibull and lognormal distributions, and its impact on the OPF problem is considered by incorporating reserve and penalty costs for overestimation and underestimation of power output. The paper also takes into account the unpredictability of power consumption (load demand) by analyzing its influence using standard probability density functions (PDF). Furthermore, practical conditions related to the thermal generators, such as ramp rate limits are examined. The MWSO algorithm is evaluated and analyzed using 23 standard benchmark functions, and a comparative study is conducted against six well-known techniques using various statistical parameters. The results and statistical analysis demonstrate the superiority and effectiveness of the MWSO algorithm compared to the original WSO algorithm for addressing the OPF problem in the presence of generation and demand uncertainties.

2.
IEEE Sens J ; 24(1): 741-749, 2024 Jan.
Artículo en Inglés | MEDLINE | ID: mdl-38344259

RESUMEN

Chronic wounds have emerged as a significant healthcare burden, affecting millions of patients worldwide and presenting a substantial challenge to healthcare systems. The diagnosis and management of chronic wounds are notably intricate, with inappropriate management contributing significantly to the amputation of limbs. In this work, we propose a compact, wireless, battery-free, and multimodal wound monitoring system to facilitate timely and effective wound treatment. The design of this monitoring system draws on the principles of higher-order parity-time symmetry, which incorporates spatially balanced gain, neutral, and loss, embodied by an active -RLC reader, an LC intermediator, and a passive RLC sensor, respectively. Our experimental results demonstrate that this wireless wound sensor can detect temperature (T), relative humidity (RH), pressure (P), and pH with exceptional sensitivity and robustness, which are critical biomarkers for assessing wound healing status. Our in vitro experiments further validate the reliable sensing performance of the wound sensor on human skin and fish. This multifunctional monitoring system may provide a promising solution for the development of futuristic wearable sensors and integrated biomedical microsystems.

3.
Sci Adv ; 9(36): eadg7481, 2023 Sep 08.
Artículo en Inglés | MEDLINE | ID: mdl-37682993

RESUMEN

Physically unclonable functions (PUFs) are a class of hardware-specific security primitives based on secret keys extracted from integrated circuits, which can protect important information against cyberattacks and reverse engineering. Here, we put forward an emerging type of PUF in the electromagnetic domain by virtue of the self-dual absorber-emitter singularity that uniquely exists in the non-Hermitian parity-time (PT)-symmetric structures. At this self-dual singular point, the reconfigurable emissive and absorptive properties with order-of-magnitude differences in scattered power can respond sensitively to admittance or phase perturbations caused by, for example, manufacturing imperfectness. Consequently, the entropy sourced from inevitable manufacturing variations can be amplified, yielding excellent PUF security metrics in terms of randomness and uniqueness. We show that this electromagnetic PUF can be robust against machine learning-assisted attacks based on the Fourier regression and generative adversarial network. Moreover, the proposed PUF concept is wavelength-scalable in radio frequency, terahertz, infrared, and optical systems, paving a promising avenue toward applications of cryptography and encryption.

4.
Neural Comput Appl ; 35(19): 13955-13981, 2023.
Artículo en Inglés | MEDLINE | ID: mdl-37234073

RESUMEN

In recent years, more efforts have been exerted to increase the level of renewable energy sources (RESs) in the energy mix in many countries to mitigate the dangerous effects of greenhouse gases emissions. However, because of their stochastic nature, most RESs pose some operational and planning challenges to power systems. One of these challenges is the complexity of solving the optimal power flow (OPF) problem in existing RESs. This study proposes an OPF model that has three different sources of renewable energy: wind, solar, and combined solar and small-hydro sources in addition to the conventional thermal power. Three probability density functions (PDF), namely lognormal, Weibull, and Gumbel, are employed to determine available solar, wind, and small-hydro output powers, respectively. Many meta-heuristic optimization algorithms have been applied for solving OPF problem in the presence of RESs. In this work, a new meta-heuristic algorithm, weighted mean of vectors (INFO), is employed for solving the OPF problem in two adjusted standard IEEE power systems (30 and 57 buses). It is simulated by MATLAB software in different theoretical and practical cases to test its validity in solving the OPF problem of the adjusted power systems. The results of the applied simulation cases in this work show that INFO has better performance results in minimizing total generation cost and reducing convergence time among other algorithms.

5.
Sensors (Basel) ; 23(7)2023 Mar 31.
Artículo en Inglés | MEDLINE | ID: mdl-37050710

RESUMEN

For the first time ever worldwide, this paper proposes, investigates, and validates, by multiple experiments, a new online automatic diagnostic technology for the belt mis-tracking of belt conveyor systems based on motor current signature analysis (MCSA). Three diagnostic technologies were investigated, experimentally evaluated, and compared for conveyor belt mis-tracking diagnosis. The proposed technologies are based on three higher-order spectral diagnostic features: bicoherence, tricoherence, and the cross-correlation of spectral moduli of order 3 (CCSM3). The investigation of the proposed technologies via comprehensive experiments has shown that technology based on the CCSM3 is highly effective for diagnosing a conveyor belt mis-tracking via MCSA.

6.
MAGMA ; 36(2): 295-308, 2023 Apr.
Artículo en Inglés | MEDLINE | ID: mdl-37072539

RESUMEN

OBJECTIVE: Wall shear stress (WSS) and its derived spatiotemporal parameters have proven to play a major role on intracranial aneurysms (IAs) growth and rupture. This study aims to demonstrate how ultra-high field (UHF) 7 T phase contrast magnetic resonance imaging (PC-MRI) coupled with advanced image acceleration techniques allows a highly resolved visualization of near-wall hemodynamic parameters patterns in in vitro IAs, paving the way for more robust risk assessment of their growth and rupture. MATERIALS AND METHODS: We performed pulsatile flow measurements inside three in vitro models of patient-specific IAs using 7 T PC-MRI. To this end, we built an MRI-compatible test bench, which faithfully reproduced a typical physiological intracranial flow rate in the models. RESULTS: The ultra-high field 7 T images revealed WSS patterns with high spatiotemporal resolution. Interestingly, the high oscillatory shear index values were found in the core of low WSS vortical structures and in flow stream intersecting regions. In contrast, maxima of WSS occurred around the impinging jet sites. CONCLUSIONS: We showed that the elevated signal-to-noise ratio arising from 7 T PC-MRI enabled to resolve high and low WSS patterns with a high degree of detail.


Asunto(s)
Aneurisma Intracraneal , Humanos , Aneurisma Intracraneal/diagnóstico por imagen , Velocidad del Flujo Sanguíneo , Imagenología Tridimensional/métodos , Imagen por Resonancia Magnética , Hemodinámica , Estrés Mecánico
7.
Micromachines (Basel) ; 14(3)2023 Mar 05.
Artículo en Inglés | MEDLINE | ID: mdl-36985010

RESUMEN

In recent decades, thriving Internet of Things (IoT) technology has had a profound impact on people's lifestyles through extensive information interaction between humans and intelligent devices. One promising application of IoT is the continuous, real-time monitoring and analysis of body or environmental information by devices worn on or implanted inside the body. This research area, commonly referred to as wearable electronics or wearables, represents a new and rapidly expanding interdisciplinary field. Wearable electronics are devices with specific electronic functions that must be flexible and stretchable. Various novel materials have been proposed in recent years to meet the technical challenges posed by this field, which exhibit significant potential for use in different wearable applications. This article reviews recent progress in the development of emerging nanomaterial-based wearable electronics, with a specific focus on their flexible substrates, conductors, and transducers. Additionally, we discuss the current state-of-the-art applications of nanomaterial-based wearable electronics and provide an outlook on future research directions in this field.

8.
ASAIO J ; 69(1): 114-121, 2023 01 01.
Artículo en Inglés | MEDLINE | ID: mdl-35435861

RESUMEN

In our retrospective multicenter study of patients 0 to 18 years of age who survived extracorporeal life support (ECLS) between January 2010 and December 2018, we sought to characterize the functional status scale (FSS) of ECLS survivors, determine the change in FSS from admission to discharge, and examine risk factors associated with development of new morbidity and unfavorable outcome. During the study period, there were 1,325 ECLS runs, 746 (56%) survived to hospital discharge. Pediatric patients accounted for 56%. Most common ECLS indication was respiratory failure (47%). ECLS support was nearly evenly split between veno-arterial and veno-venous (51% vs . 49%). Median duration of ECLS in survivors was 5.5 days. Forty percent of survivors had new morbidity, and 16% had an unfavorable outcome. In a logistic regression, African American patients (OR 1.68, p = 0.01), longer duration of ECLS (OR 1.002, p = 0.004), mechanical (OR 1.79, p = 0.002), and renal (OR 1.64, p = 0.015) complications had higher odds of new morbidity. Other races (Pacific Islanders, and Native Americans) (OR 2.89, p = 0.013), longer duration of ECLS (OR 1.002, p = 0.002), and mechanical complications (OR 1.67, p = 0.026) had higher odds of unfavorable outcomes. In conclusion, in our multi-center 9-year ECLS experience, 56% survived, 40% developed new morbidity, and 84% had favorable outcome. Future studies with larger populations could help identify modifiable risk factors that could help guide clinicians in this fragile patient population.


Asunto(s)
Estado Funcional , Insuficiencia Respiratoria , Humanos , Niño , Lactante , Adolescente , Insuficiencia Respiratoria/terapia , Estudios Retrospectivos , Alta del Paciente , Factores de Tiempo
9.
Micromachines (Basel) ; 15(1)2023 Dec 22.
Artículo en Inglés | MEDLINE | ID: mdl-38258145

RESUMEN

The intersection of biomedicine and radio frequency (RF) engineering has fundamentally transformed self-health monitoring by leveraging soft and wearable electronic devices. This paradigm shift presents a critical challenge, requiring these devices and systems to possess exceptional flexibility, biocompatibility, and functionality. To meet these requirements, traditional electronic systems, such as sensors and antennas made from rigid and bulky materials, must be adapted through material science and schematic design. Notably, in recent years, extensive research efforts have focused on this field, and this review article will concentrate on recent advancements. We will explore the traditional/emerging materials for highly flexible and electrically efficient wearable electronics, followed by systematic designs for improved functionality and performance. Additionally, we will briefly overview several remarkable applications of wearable electronics in biomedical sensing. Finally, we provide an outlook on potential future directions in this developing area.

10.
Sensors (Basel) ; 22(23)2022 Dec 05.
Artículo en Inglés | MEDLINE | ID: mdl-36502207

RESUMEN

Due to the wide use of gearmotor systems in industry, many diagnostic techniques have been developed/employed to prevent their failures. An insufficient lubrication of gearboxes of these machines could shorten their life and lead to catastrophic failures and losses, making it important to ensure a required lubrication level. For the first time in worldwide terms, this paper proposed to diagnose a lack of gearbox oil lubrication using motor current signature analysis (MCSA). This study proposed, investigated, and experimentally validated two new technologies to diagnose a lack of lubrication of gear motor systems based on MCSA. Two new diagnostic features were extracted from the current signals of a three-phase induction motor. The effectiveness of the proposed technologies was evaluated for different gear lubrication levels and was compared for three phases of motor current signals and for a case of averaging the proposed diagnostic features over three phases. The results confirmed a high effectiveness of the proposed technologies for diagnosing a lack of oil lubrication in gearmotor systems. Other contributions were as follows: (i) it was shown for the first time in worldwide terms, that the motor current nonlinearity level increases with the reduction of the sgearbox oil level; (ii) novel experimental validations of the proposed two diagnostic technologies via comprehensive experimental trials (iii) novel experimental comparisons of the diagnosis effectiveness of the proposed two diagnostic technologies.


Asunto(s)
Aceites , Humanos , Equipo para Diagnóstico
11.
IEEE Trans Biomed Circuits Syst ; 16(2): 287-295, 2022 04.
Artículo en Inglés | MEDLINE | ID: mdl-35380967

RESUMEN

Vital signal monitoring, such as pulse, respiration rate, intra-organ and intra-vascular pressure, can provide important information for determination of clinic diagnosis, treatments, and surgical protocols. Nowadays, micromachined bioimplants, equipped with antennas for converting bio-signals to modulated radio transmissions, may allow remote continuous monitoring of patients' vital signs. Yet, current passive biotelemetry techniques usually suffer from poor signal reproducibility and robustness in light of inevitable misalignment between transmitting and receiving antennas. Here, we seek to address this long-existing challenge and to robustly acquire information from a passive wireless intracranial pressure (or brain pressure) sensor by introducing a novel, high-performance biotelemetry system. In spite of variable inductive links, this biotelemetry system may have absolute accuracy by leveraging the uniqueness of loci of exceptional points (EPs) in non-Hermitian radio-frequency (RF) electronic systems with parity-time (PT) symmetry. Our in-vitro experimental demonstration shows that the proposed intracranial (ICP) monitoring system can provide a sub-mmHg resolution in the ICP range of 0-20 mmHg and ultra-robust wireless data acquisition against the misalignment-induced weakening of inductive link. Our results could provide a practical pathway toward reliable, real-time wireless monitoring of ICP, and other vital signals generated by bio-implants and wearables.


Asunto(s)
Presión Intracraneal , Prótesis e Implantes , Humanos , Monitoreo Fisiológico/métodos , Reproducibilidad de los Resultados , Signos Vitales , Tecnología Inalámbrica
12.
Pediatr Crit Care Med ; 23(2): 79-88, 2022 02 01.
Artículo en Inglés | MEDLINE | ID: mdl-35119428

RESUMEN

OBJECTIVES: Sepsis-induced immunoparalysis represents a pathologic downregulation of leukocyte function shown to be associated with adverse outcomes, although its mechanisms remain poorly understood. Our goal was to compare genome-wide gene expression profiles of immunoparalyzed and nonimmunoparalyzed children with sepsis to identify genes and pathways associated with immunoparalysis. DESIGN: Prospective observational study. PATIENTS: Twenty-six children with lower respiratory tract infection meeting criteria for sepsis, severe sepsis, or septic shock admitted to the PICU. SETTING: Two tertiary care PICUs. INTERVENTIONS: None. MEASUREMENTS AND MAIN RESULTS: Innate immune function was assayed ex vivo by measuring release of tumor necrosis factor-α from whole blood after incubation with lipopolysaccharide for 4 hours. Immunoparalysis was defined as a tumor necrosis factor-α production capacity less than 200 pg/mL. Ten of the 26 children were immunoparalyzed. There were 17 significant differentially expressed genes when comparing genome-wide gene expression profiles of immunoparalyzed and nonimmunoparalyzed children (false discovery rate < 0.05). Nine genes showed increased expression in immunoparalyzed children (+1.5- to +8.8-fold change). Several of these dampen the immune system. Eight showed decreased expression in immunoparalyzed children (-1.7- to -3.9-fold change), several of which are involved in early regulation and activation of immune function. Functional annotation clustering using differentially expressed genes with p value of less than 0.05 showed three clusters related to immunity with significant enrichment scores (2.2-4.5); the most significant gene ontology terms in these clusters were antigen processing and presentation and negative regulation of interleukin-6 production. Network analysis identified potential protein interactions that may be involved in the development of immunoparalysis in children. CONCLUSIONS: In this exploratory analysis, immunoparalyzed children with sepsis showed increased expression of genes that dampen the immune system and decreased expression of genes involved in regulation and activation of the immune system. Analysis also implicated other proteins as potentially having as yet unidentified roles in the development of immunoparalysis.


Asunto(s)
Sepsis , Choque Séptico , Niño , Humanos , Proyectos Piloto , Estudios Prospectivos , Choque Séptico/genética , Factor de Necrosis Tumoral alfa/genética , Factor de Necrosis Tumoral alfa/metabolismo
13.
Front Oncol ; 12: 1025481, 2022.
Artículo en Inglés | MEDLINE | ID: mdl-36713528

RESUMEN

Sonosensitive perfluorocarbon F8TAC18-PFOB emulsion is under development to enhance heating, increase thermal contrast, and reduce treatment times during focused ultrasound tumor ablation of highly perfused tissue. The emulsion previously showed enhanced heating during ex vivo and in vitro studies. Experiments were designed to observe the response in additional scenarios by varying focused ultrasound conditions, emulsion concentrations, and surfactants. Most notably, changes in acoustic absorption were assessed with MR-ARFI. Phantoms were developed to have thermal, elastic, and relaxometry properties similar to those of ex vivo pig tissue. The phantoms were embedded with varying amounts of F8TAC18-PFOB emulsion or lecithin-PFOB emulsion, between about 0.0-0.3% v:w, in 0.05% v:w increments. MR-ARFI measurements were performed using a FLASH-ARFI-MRT sequence to obtain simultaneous displacement and temperature measurements. A Fabry-Perot hydrophone was utilized to observe the acoustic emissions. Susceptibility-weighted imaging and relaxometry mapping were performed to observe concentration-dependent effects. 19F diffusion-ordered spectroscopy NMR was used to measure the diffusion coefficient of perfluorocarbon droplets in a water emulsion. Increased displacement and temperature were observed with higher emulsion concentration. In semi-rigid MR-ARFI phantoms, a linear response was observed with low-duty cycle MR-ARFI sonications and a mono-exponential saturating response was observed with sustained sonications. The emulsifiers did not have a significant effect on acoustic absorption in semi-rigid gels. Stable cavitation might also contribute to enhanced heating.

14.
Sensors (Basel) ; 20(8)2020 Apr 20.
Artículo en Inglés | MEDLINE | ID: mdl-32326060

RESUMEN

We propose a spectrometer-free refractive index sensor based on a graphene plasmonic structure. The spectrometer-free feature of the device is realized thanks to the dynamic tunability of graphene's chemical potential, through electrostatic biasing. The proposed sensor exhibits a 1566 nm/RIU sensitivity, a 250.6 RIU-1 figure of merit in the optical mode of operation and a 713.2 meV/RIU sensitivity, a 246.8 RIU-1 figure of merit in the electrical mode of operation. This performance outlines the optimized operation of this spectrometer-free sensor that simplifies its design and can bring terahertz sensing one step closer to its practical realization, with promising applications in biosensing and/or gas sensing.

15.
Magn Reson Med ; 81(1): 560-572, 2019 01.
Artículo en Inglés | MEDLINE | ID: mdl-29893989

RESUMEN

PURPOSE: The morphological and hemodynamic evaluations of neurovascular diseases treated with stents would benefit from noninvasive imaging techniques such as 3D time-of-flight MRI (3D-TOF) and 3D phase contrast MRI (3D-PCMRI). For this purpose, a comprehensive evaluation of the stent artifacts and their impact on the flow measurement is critical. METHODS: The artifacts of a representative sample of neurovascular stents were evaluated in vitro with 3D-TOF and 3D-PCMRI sequences. The dependency of the artifacts with respect to the orientation was analyzed for each stent design as well as the impact on the flow measurement accuracy. Furthermore, the 3D-PCMRI data of four patients carrying intracranial aneurysms treated with flow diverter stents were analyzed as illustrative examples. RESULTS: The stent artifacts were mainly confined to the stent lumen therefore indicating the leading role of shielding effect. The influence of the stent design and its orientation with respect to the transmitting MR coils were highlighted. The artifacts impacted the 3D-PCMRI velocities mainly in the low magnitude domains, which were discarded from the analysis ensuring reliable near-stent velocities. The feasibility of in-stent flow measurements was confirmed in vivo on two patients who showed strong correlation between flow and geometric features. In two other patients, the consistency of out-of-stent velocities was verified qualitatively through intra-aneurysmal streamlines except when susceptibility artifacts occurred. CONCLUSION: The present results motivate the conception of low inductance or nonconductive stent design. Furthermore, the feasibility of near-stent 3D-PCMRI measurements opens the door to clinical applications like the post-treatment follow-up of stenoses or intracranial aneurysms.


Asunto(s)
Aneurisma/diagnóstico por imagen , Imagenología Tridimensional , Imagen por Resonancia Magnética , Neuronas/metabolismo , Stents , Algoritmos , Artefactos , Velocidad del Flujo Sanguíneo , Vasos Sanguíneos/metabolismo , Circulación Cerebrovascular , Cromo/química , Cobalto/química , Hemodinámica , Humanos , Aneurisma Intracraneal/diagnóstico por imagen , Ensayo de Materiales , Níquel/química , Reproducibilidad de los Resultados , Titanio/química , Procedimientos Quirúrgicos Vasculares/efectos adversos
16.
Int J Pediatr ; 2018: 5450697, 2018.
Artículo en Inglés | MEDLINE | ID: mdl-30532791

RESUMEN

OBJECTIVE: The study was undertaken to determine the etiology, review management, and outcome in children diagnosed with acute pericarditis during 11 years at tertiary pediatric institution. METHODS: Retrospective chart review of children diagnosed between 2004 and 2014. Patients with postsurgical pericardial effusions were excluded. RESULTS: Thirty-two children were identified (median age 10yr/11mo). Pericardiocentesis was performed in 24/32 (75%) patients. The most common cause of pericarditis was infection in 11/32 (34%), followed by inflammatory disorders in 9 (28%). Purulent pericarditis occurred in 5 children including 4 due to Staphylococcus aureus: 2 were methicillin resistant (MRSA). All patients with purulent pericarditis had concomitant infection including soft tissue, bone, or lung infection; all had pericardial drain placement and 2 required pericardiotomy and mediastinal exploration. Other infections were due to Histoplasma capsulatum (2), Mycoplasma pneumoniae (2), Influenza A (1), and Enterovirus (1). Pericarditis/pericardial effusion was the initial presentation in 4 children with systemic lupus erythematosus including one who presented with tamponade and in 2 children who were diagnosed with systemic onset juvenile inflammatory arthritis. Tumors were diagnosed in 2 patients. Five children had recurrent pericarditis. Systemic antibiotics were used in 21/32 (66%) and prednisone was used in 11/32 (34%) patients. CONCLUSION: Infections remain an important cause of pericarditis in children. Purulent pericarditis is most commonly caused by Staphylococcus aureus and is associated with significant morbidity, need of surgical intervention, and prolonged antibiotic therapy. Echocardiography-guided thoracocentesis remains the preferred diagnostic and therapeutic approach. However, pericardiotomy and drainage are needed when appropriate clinical response is not achieved with percutaneous drainage.

17.
Opt Express ; 26(19): 24792-24803, 2018 Sep 17.
Artículo en Inglés | MEDLINE | ID: mdl-30469591

RESUMEN

We make use of transformation optics technique to realize cloaking operation in the light diffusive regime, for spherical objects. The cloak requires spatially heterogeneous anisotropic diffusivity, as well as spatially varying speed of light and absorption. Analytic calculations of Photon's fluence confirm minor role of absorption in reduction of far-field scattering, and a monopole fluence field converging to a constant in the static regime in the invisibility region. The latter is in contrast to acoustic and electromagnetic cloaks, for which the field vanishes inside the core. These results are finally discussed in the context of mass diffusion, where cloaking can be achieved with a heterogeneous anisotropic diffusivity.

18.
Int J Health Sci (Qassim) ; 12(3): 25-28, 2018.
Artículo en Inglés | MEDLINE | ID: mdl-29896068

RESUMEN

OBJECTIVE: To study the effect of thyroidectomy with totally preserved recurrent laryngeal nerve (RLN) on the objective vocal functions. METHODOLOGY: It is a prospective pilot study of 10 patients undergoing thyroid surgery on whom to study the effect of thyroidectomy with totally preserved RLN on the objective vocal functions. Patient history and demographic data were collected at the time of admission and in each period of assessment average fundamental frequency; absolute jitter, shimmer, and others were measured. Furthermore, one-way analysis of variance (ANOVA) repeated measurements statistical technique was used to test the difference among the 3 time period of measurements and P < 0.05 was considered significant (α = 0.05). RESULTS: The mean age was 39.5 ± 3.31 years. There were two males and eight females. Total thyroidectomy was performed on eight patients while one had left hemithyroidectomy and one completion thyroidectomy. Histopathology revealed papillary thyroid carcinoma in 50%. 34 acoustic voice analysis parameters were measured using the multidimensional voice program, which showed no significant differences at the end of 1st and 3rd month post-operative as compared to the pre-operative measurements. There was no significant difference in measurement for each factor over the time (P > 0.05). CONCLUSIONS: All the acoustic analysis parameters for 10 patients showed no significant differences in 1st and 3rd month postoperatively as compared to the pre-operative values. However, due to small sample size, our study may have failed to detect any significant difference.

19.
Magn Reson Med ; 79(1): 129-140, 2018 Jan.
Artículo en Inglés | MEDLINE | ID: mdl-28244132

RESUMEN

PURPOSE: Recent advances in 3D-PCMRI (phase contrast MRI) sequences allow for measuring the complex hemodynamics in cerebral arteries. However, the small size of these vessels vs spatial resolution can lead to non-negligible partial volume artifacts, which must be taken into account when computing blood flow rates. For this purpose, we combined the velocity information provided by 3D-PCMRI with vessel geometry measured with 3DTOF (time of flight MRI) or 3DRA (3D rotational angiography) to correct the partial volume effects in flow rate assessments. METHODS: The proposed methodology was first tested in vitro on cylindrical and patient specific vessels subject to fully controlled pulsatile flows. Both 2D- and 3D-PCMRI measurements using various spatial resolutions ranging from 20 to 1.3 voxels per vessel diameter were analyzed and compared with flowmeter baseline. Second, 3DTOF, 2D- and 3D-PCMRI measurements were performed in vivo on 35 patients harboring internal carotid artery (ICA) aneurysms indicated for endovascular treatments requiring 3DRA imaging. RESULTS: The in vitro 2D- and 3D-PCMRI mean flow rates assessed with partial volume correction showed very low sensitivity to the acquisition resolution above ≈2 voxels per vessel diameter while uncorrected flow rates deviated critically when decreasing the spatial resolution. 3D-PCMRI flow rates measured in vivo in ICA agreed very well with 2D-PCMRI data and a good flow conservation was observed at the C7 bifurcation. Globally, partial volume correction led to 10-15% lower flow rates than uncorrected values as those reported in most of the published studies on intracranial flows. CONCLUSION: Partial volume correction may improve the accuracy of PCMRI flow rate measurements especially in small vessels such as intracranial arteries. Magn Reson Med 79:129-140, 2018. © 2017 International Society for Magnetic Resonance in Medicine.


Asunto(s)
Arteria Carótida Interna/diagnóstico por imagen , Imagenología Tridimensional/métodos , Imagen por Resonancia Magnética/métodos , Adulto , Artefactos , Velocidad del Flujo Sanguíneo , Arterias Cerebrales/diagnóstico por imagen , Circulación Cerebrovascular , Femenino , Hemodinámica , Humanos , Aneurisma Intracraneal/patología , Masculino , Persona de Mediana Edad , Modelos Estadísticos , Flujo Pulsátil
20.
Phys Rev E ; 96(3-1): 033114, 2017 Sep.
Artículo en Inglés | MEDLINE | ID: mdl-29347011

RESUMEN

Presented here are observations that demonstrate how the deformation of millimetric cavitation bubbles by a uniform pressure gradient quenches single-collapse luminescence. Our innovative measurement system captures a broad luminescence spectrum (wavelength range, 300-900 nm) from the individual collapses of laser-induced bubbles in water. By varying the bubble size, driving pressure, and perceived gravity level aboard parabolic flights, we probed the limit from aspherical to highly spherical bubble collapses. Luminescence was detected for bubbles of maximum radii within the previously uncovered range, R_{0}=1.5-6 mm, for laser-induced bubbles. The relative luminescence energy was found to rapidly decrease as a function of the bubble asymmetry quantified by the anisotropy parameter ζ, which is the dimensionless equivalent of the Kelvin impulse. As established previously, ζ also dictates the characteristic parameters of bubble-driven microjets. The threshold of ζ beyond which no luminescence is observed in our experiment closely coincides with the threshold where the microjets visibly pierce the bubble and drive a vapor jet during the rebound. The individual fitted blackbody temperatures range between T_{lum}=7000 and T_{lum}=11500 K but do not show any clear trend as a function of ζ. Time-resolved measurements using a high-speed photodetector disclose multiple luminescence events at each bubble collapse. The averaged full width at half-maximum of the pulse is found to scale with R_{0} and to range between 10 and 20 ns.

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