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1.
Sci Rep ; 13(1): 8268, 2023 05 22.
Artículo en Inglés | MEDLINE | ID: mdl-37217491

RESUMEN

The use of metal phosphides, particularly aluminum phosphide, poses a significant threat to human safety and results in high mortality rates. This study aimed to determine mortality patterns and predictive factors for acute zinc and aluminum phosphide poisoning cases that were admitted to Menoufia University Poison and Dependence Control Center from 2017 to 2021. Statistical analysis revealed that poisoning was more common among females (59.7%), aged between 10 and 20 years, and from rural regions. Most cases were students, and most poisonings were the result of suicidal intentions (78.6%). A new hybrid model named Bayesian Optimization-Relevance Vector Machine (BO-RVM) was proposed to forecast fatal poisoning. The model achieved an overall accuracy of 97%, with high positive predictive value (PPV) and negative predictive value (NPV) values of 100% and 96%, respectively. The sensitivity was 89.3%, while the specificity was 100%. The F1 score was 94.3%, indicating a good balance between precision and recall. These results suggest that the model performs well in identifying both positive and negative cases. Additionally, the BO-RVM model has a fast and accurate processing time of 379.9595 s, making it a promising tool for various applications. The study underscores the need for public health policies to restrict the availability and use of phosphides in Egypt and adopt effective treatment methods for phosphide-poisoned patients. Clinical suspicion, positive silver nitrate test for phosphine, and analysis of cholinesterase levels are useful in diagnosing metal phosphide poisoning, which can cause various symptoms.


Asunto(s)
Plaguicidas , Fosfinas , Intoxicación , Venenos , Femenino , Humanos , Niño , Adolescente , Adulto Joven , Adulto , Aluminio , Teorema de Bayes , Compuestos de Aluminio , Intoxicación por Metales Pesados
2.
PLoS One ; 18(5): e0284110, 2023.
Artículo en Inglés | MEDLINE | ID: mdl-37196020

RESUMEN

Several optimization problems can be abstracted into many-objective optimization problems (MaOPs). The key to solving MaOPs is designing an effective algorithm to balance the exploration and exploitation issues. This paper proposes a novel many-objective African vulture optimization algorithm (MaAVOA) that simulating the African vultures' foraging and navigation behaviours to solve the MaOPs. MaAVOA is an updated version of the African Vulture Optimization Algorithm (AVOA), which was recently proposed to solve the MaOPs. A new social leader vulture for the selection process is introduced and integrated into the proposed model. In addition, an environmental selection mechanism based on the alternative pool is adapted to improve the selection process to maintain diversity for approximating different parts of the whole Pareto Front (PF). The best-nondominated solutions are saved in an external Archive based on the Fitness Assignment Method (FAM) during the population evolution. FAM is based on a convergence measure that promotes convergence and a density measure that promotes variety. Also, a Reproduction of Archive Solutions (RAS) procedure is developed to improve the quality of archiving solutions. RAS has been designed to help reach out to the missing areas of the PF that the vultures easily miss. Two experiments are conducted to verify and validate the suggested MaAVOA's performance efficacy. First, MaAVOA was applied to the DTLZ functions, and its performance was compared to that of several popular many-objective algorithms and according to the results, MaAVOA outperforms the competitor algorithms in terms of inverted generational distance and hypervolume performance measures and has a beneficial adaptation ability in terms of both convergence and diversity performance measures. Also, statistical tests are implemented to demonstrate the suggested algorithm's statistical relevance. Second, MaAVOA has been applied to solve two real-life constrained engineering MaOPs applications, namely, the series-parallel system and overspeed protection for gas turbine problems. The experiments show that the suggested algorithm can tackle many-objective real-world applications and provide promising choices for decision-makers.


Asunto(s)
Algoritmos , Simulación por Computador
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