Asunto(s)
Enfermedades de los Perros/patología , Intoxicación por Mercurio/veterinaria , Animales , Enfermedades del Sistema Nervioso Central/inducido químicamente , Enfermedades del Sistema Nervioso Central/patología , Enfermedades del Sistema Nervioso Central/veterinaria , Perros , Femenino , Intoxicación por Mercurio/patologíaRESUMEN
The purpose of this work was to study the association of positive serological titers to Ehrlichia risticii, the causative agent of equine monocytic ehrlichiosis (EME) with gastro-intestinal disorders in hospitalized horses referred to The Ohio State University College of Veterinary Medicine Teaching Hospital (OSU VMTH). In addition, serological titers for E. risticii were monitored in two horse populations with endemic EME for one season to monitor temporal changes in titers. A statistically significant difference was found between the proportion of the total hospitalized horse population presented with a gastro-intestinal disorder during the study period, and study horses with IFA titers > or = 1:80 with these signs (P < 0.05). No such difference was found between the proportion of the total hospital horse population presented with signs of gastro-intestinal disorder, and the study horses with IFA titers of 1:20-1:40 with these signs, suggesting that these titers may not have any clinical significance for EME (P > 0.05). Thirty-eight horses on two farms endemic for EME were tested approximately every 3 weeks, 33 of which were tested serially at least two times. Five of the 38 horses (13.2%) had IFA titers > or = 1:80--two that were positive initially and three that seroconverted during the study; 15 horses' titers fluctuated between negative (IFA titers < 1:20) and exposed titers (1:20 through 1:40); and 18 horses remained negative throughout the study.
Asunto(s)
Anticuerpos Antibacterianos/sangre , Ehrlichiosis/veterinaria , Enfermedades Gastrointestinales/veterinaria , Enfermedades de los Caballos/inmunología , Animales , Ehrlichiosis/sangre , Ehrlichiosis/complicaciones , Ehrlichiosis/epidemiología , Ehrlichiosis/inmunología , Femenino , Técnica del Anticuerpo Fluorescente/veterinaria , Estudios de Seguimiento , Enfermedades Gastrointestinales/sangre , Enfermedades Gastrointestinales/etiología , Enfermedades Gastrointestinales/inmunología , Enfermedades de los Caballos/sangre , Enfermedades de los Caballos/epidemiología , Caballos , MasculinoRESUMEN
A 15-year-old mare mule was presented with a 2-month history of weight loss, lethargy, and anorexia. Clinicopathologic abnormalities were consistent with liver disease. Repeated urinalysis revealed hyposthenuria, but water intake and a water deprivation test were normal, suggesting adequate renal function. Ultrasonography revealed pulmonary, hepatic, and renal masses. Cytologic and histologic examination of pulmonary aspirates and hepatic biopsies, respectively, revealed polygonal neoplastic cells with many mitotic figures, the cells having the characteristics of adenocarcinoma. Necropsy confirmed a primary renal adenocarcinoma with metastasis to liver, lung, lymph nodes and the opposite kidney.
