Distrofia en huella dactilar: brotes de astigmatismo irregular y su demostración topográfica / Fingerprint microcystic dystrophy: Episodes of irregular astigmatism and their topographical representation

Caso clínico: Varón de 44 años con brotes indoloros de visión borrosa sin repercusión oftalmológica visible inicialmente. Tras uno de sus episodios, se visualiza en polo anterior imágenes en huella digital así como cambios corneales, paquimétricos y topográficos que originan cambios refractivos sintomáticos. Discusión: La distrofia en huella dactilar es una entidad diagnosticada por erosiones corneales recurrentes. Su base patogénica, una membrana basal epitelial alterada, favorece la separación del epitelio corneal de las capas subyacentes. En la medida que ésta sea total o parcial ocasionará erosiones corneales recurrentes o, con menor frecuencia, episodios de visión borrosa por edema y engrosamiento corneal(AU)

Case Study: A 44 year-old male patient suffering from painless bouts of blurred vision and with no visible ophthalmological repercussions initially. After one of these clinical episodes we managed to visualise fingerprint images in the anterior pole, as well as corneal, pachymetric and topographical changes, which in turn produce the symptomatic refractive changes. Discussion: Fingerprint keratopathy is a condition diagnosed through recurring corneal erosion. The pathogenic origin of the condition-an altered epithelial basal membrane- may encourage the separation of the corneal epithelium from its underlying layers. Depending on whether this separation is partial or total, this will lead to spontaneous corneal erosion or, less frequently, episodes of blurred vision caused by oedema and corneal swelling(AU)

[Fingerprint microcystic dystrophy: Episodes of irregular astigmatism and their topographical representation]. / Distrofia en huella dactilar: brotes de astigmatismo irregular y su demostración topográfica.

CASE STUDY: A 44 year-old male patient suffering from painless bouts of blurred vision and with no visible ophthalmological repercussions initially. After one of these clinical episodes we managed to visualise fingerprint images in the anterior pole, as well as corneal, pachymetric and topographical changes, which in turn produce the symptomatic refractive changes. DISCUSSION: Fingerprint keratopathy is a condition diagnosed through recurring corneal erosion. The pathogenic origin of the condition-an altered epithelial basal membrane- may encourage the separation of the corneal epithelium from its underlying layers. Depending on whether this separation is partial or total, this will lead to spontaneous corneal erosion or, less frequently, episodes of blurred vision caused by oedema and corneal swelling.

Effects of the administration of artroglobina suppositories in healthy volunteers.

Forty-nine healthy volunteers were treated daily with Artroglobina suppositories (anticartilage antiparathyroid immunoglobulins) for twelve days, in order to prove the absence of side effects. Volunteers were examined daily. Blood and urine samples were taken before the treatment, twelve days, twenty-four days and six months after the beginning of the treatment. Slight changes were noted in some parameters though remaining in the normal range and disappearing six months later. No symptoms of intolerance, toxicity or side effects were registered.