1.
BMJ Case Rep
; 20172017 Nov 03.
Artículo
en Inglés
| MEDLINE
| ID: mdl-29102978
Asunto(s)
Anticoagulantes/efectos adversos , Cuidados Críticos , Craniectomía Descompresiva/métodos , Hematoma Subdural/inducido químicamente , Estenosis de la Válvula Mitral/tratamiento farmacológico , Tomografía Computarizada por Rayos X , Anticoagulantes/uso terapéutico , Preescolar , Electrocardiografía , Femenino , Hematoma Subdural/diagnóstico por imagen , Hematoma Subdural/fisiopatología , Hematoma Subdural/cirugía , Humanos , Ictericia , Estenosis de la Válvula Mitral/congénito , Estenosis de la Válvula Mitral/fisiopatología , Neuroimagen , Prurito , Resultado del Tratamiento
2.
J Neuroimmunol
; 219(1-2): 47-53, 2010 Feb 26.
Artículo
en Inglés
| MEDLINE
| ID: mdl-20034680
RESUMEN
B cells are of increasing importance as a target for multiple sclerosis treatment. Here we show that GA treatment of mice with experimental autoimmune encephalomyelitis (EAE) biases cytokine production by B cells towards cytokines associated with regulation in MS including interleukin (IL)-4, -10 and -13 and reduces pro-inflammatory IL-6, IL-12, and TNF alpha levels. GA also down-regulates expression of B cell-activating factor (BAFF) of the TNF family and a proliferation-inducing ligand (APRIL), as well as the BAFF receptor in mice with EAE. Thus, GA impacts both B cell survival and B cell cytokine production during CNS inflammatory disease in an EAE model.