RESUMEN
Metal-organic frameworks (MOFs) as types of proton conductive materials have attracted much attention. Here, an acylamide-functionalized 3D MOF, [Ni3(TPBTC)2(stp)2(H2O)4]·2DMA·32H2O, has been successfully constructed via combining Ni(NO3)2, TPBTC (TPBTC = benzene-1,3,5-tricarboxylic acid tris-pyridin-4-ylamide) and 2-H2stp (2-H2stp = 2-sulfoterephthalic acid monosodium salt) under solvothermal conditions. Single-crystal X-ray diffraction revealed that there are uncoordinated guest DMA molecules in the pores of the compound. On removal of guest DMA molecules, the proton conductivity of the compound increased to 2.25 × 10-3 S cm-1 at 80 °C and 98% RH which is about 110 times that of the original material. It is hoped that this work can provide essential insight for designing and obtaining improved crystalline-state proton conducting materials by considering the influences of guest molecules on proton conduction properties of porous materials.
RESUMEN
Biochanin A (BCA), an isoflavone derived from various plants such as chickpea, red clover and soybean, is attracting increasing attention and is considered to have applications in the development of pharmaceuticals and nutraceuticals due to its anti-inflammatory, anti-oxidant, anti-cancer and neuroprotective properties. To design optimised and targeted BCA formulations, on one hand there is a need for more in-depth studies on the biological functions of BCA. On the other hand, further studies on the chemical conformation, metabolic composition and bioavailability of BCA need to be conducted. This review highlights the various biological functions, extraction methods, metabolism, bioavailability, and application prospects of BCA. It is hoped that this review will provide a basis for understanding the mechanism, safety and toxicity of BCA and implementing the development of BCA formulations.
RESUMEN
Three new cucurbit[6]uril (CB[6])-based metal-organic rotaxane networks (MORNs) (named CUST-711, CUST-712, and CUST-713) functionalized by a sulfonic group (-SO3H) have been designed and synthesized via a hydrothermal method. All three compounds exhibited similar two-dimensional (2D) wave layer structures. Their stability under different temperature and relative humidity conditions has been investigated and all the compounds showed excellent stability. Furthermore, their proton conduction properties were also discussed in detail. Due to different structures and sulfonic group sites, the three compounds exhibited different proton conduction abilities of which CUST-712 exhibited an intrinsic relatively high proton conductivity (1.75 × 10-4 S cm-1 at 85 °C and 97% relative humidity). These results provide ideas for the design and synthesis of functional CB[6]-based metal-organic rotaxane frameworks (MORFs) as proton conducting materials.
RESUMEN
OBJECTIVE: To study and compare the clinical efficacies and characteristics of VCu intrauterine device (IUD) and TCu380A IUD in childbearing-aged women with previous cesarean section so as to provide rationales for an informed choice of contraceptive methods. METHODS: According to their physical status, a total of 400 women undergoing previous cesarean section were randomly provided VCu IUD and TCu380A IUD from February 2008 to August 2009. These healthy women were had no contraindication to IUD. The volunteers required voluntarily the placement of IUD. Then all of them were followed up for 3, 6 and 12 months. RESULTS: At Month 12, the pregnant rate with IUD in situ of VCu and TCu380A IUD were 1.02% and 4.64%, expulsion rate 0 and 3.1% and withdrawing rate 1.02% and 4.13% respectively. The pregnant rate was significantly different (P < 0.05); VCu showed a lower expulsion and withdrawing rate than that in TCu380A (P < 0.05); the continuation rate of VCu was higher than that of TCu380A (P < 0.05). CONCLUSION: VCu offers a better efficacy of contraception with a lower expulsion and withdrawing rate, a higher continuation rate and a simpler placement method.
