Masa retroperitoneal gigante en el tumor periférico de la vaina neural asociado a neurofibromatosis tipo 1. Reporte de un caso y revisión de la literatura / Giant retroperitoneal mass in peripheral neural sheath tumor associated with neurofibromatosis type 1. Case report and review of the literature

Los tumores malignos de vaina neural periférica (MPNST) se observan con mayor frecuencia en pacientes con neurofibromatosis tipo 1 (NF-1), presentando un crecimiento rápido y unas tasas de supervivencia a los 5 años alrededor del 33%. Presentamos el caso de un varón de 17 años afecto de NF-1 con un MPNST retroperitoneal gigante sometido a tratamiento quirúrgico radical, con recidiva tumoral precoz

Malignant peripheral nerve sheath tumors (MPNST) are most frequently in patients with neurofibromatosis type 1 (NF-1), with a rapid growth and 5-years survival rates around 33%. We present the case of a 17 years old male with NF-1 and a giant retroperi-toneal MPNST who undergoes a radical surgical treatment, with early tumor recurrence

Imiquimod 5% tópico como terapia alternativa en carcinoma basocelular periocular en 2 pacientes con contraindicación quirúrgica / Topical imiquimod 5% as an alternative therapy in periocular basal cell carcinoma in two patients with surgical contraindication

CASO CLÍNICOS: Presentamos los casos de dos pacientes con carcinoma basocelular periocular palpebral, que recibieron imiquimod tópico al 5%, con buena respuesta. Ambos presentaban un estado funcional que desaconsejaba el tratamiento quirúrgico. CONCLUSIÓN: La crema de imiquimod al 5% ha demostrado ser una alternativa eficaz al tratamiento quirúrgico de tumores basocelulares perioculares, especialmente en aquellos casos en los que la cirugía no es posible

CLINICAL CASE: The cases are presented of two patients with periocular basal cell carcinoma of the eyelid who received topical imiquimod 5%, with a good response. Both had a functional state that contraindicated surgical treatment. CONCLUSION: Imiquimod cream 5% was shown to be an effective alternative to surgical treatment of periocular basal cell carcinoma, especially in those cases where surgery is not possible

Topical imiquimod 5% as an alternative therapy in periocular basal cell carcinoma in two patients with surgical contraindication. / Imiquimod 5% tópico como terapia alternativa en carcinoma basocelular periocular en 2 pacientes con contraindicación quirúrgica.

CLINICAL CASES: The cases are presented of two patients with periocular basal cell carcinoma of the eyelid who received topical imiquimod 5%, with a good response. Both had a functional state that contraindicated surgical treatment. CONCLUSION: Imiquimod cream 5% was shown to be an effective alternative to surgical treatment of periocular basal cell carcinoma, especially in those cases where surgery is not possible.

Long-term evaluation of the central vault after phakic Collamer® lens (ICL) implantation using OCT.

PURPOSE: The aim of this work is to evaluate the changes in the central vault after using implantable Collamer® lenses (ICL) to correct myopia. METHODS: This cohort study included 133 eyes; mean spherical equivalent -9.47 ± 3.71 diopters (D) (range: -2.75 to -22.25 D) who underwent ICL V4 implantation. Besides a complete ophthalmologic examination, the central vaulting was measured with Visante OCT and evaluated between different periods of follow-up (1 week, 1, 3, and 6 months, and yearly postoperatively). Post-operative time ranged from 6 to 73 months. RESULTS: Within the first 6 months, the mean central vaulting dropped from 510 ± 238 µm (range 100 to 940 µm) to 439 ± 231 µm (range 90 to 910) a significant decrease by 71 ± 58 µm (range -170 to 30 µm) (p = 0.028) with a trend to a lower reduction after this period. After 36 month from ICL implantation, this variation tends to be smaller with the majority of the eyes having a mean decrease smaller than 2 µm per month. Initial vault (Spearman Rho = -0.237, p = 0.006) was the factor more significantly associated with decrease in vault; eyes presenting a reduction in vault >100 µm had an average initial vault that was 141 µm and 184 µm higher than eyes with no change or with increase in vault over time, respectively. CONCLUSIONS: This study shows a continuous reduction of central vault over time. The reduction is highest during the first 6 months and tends to be lower and slow down over time. The decrease of vaulting was more pronounced in eyes with larger initial vaulting.

[Deformity of the nasal pyramid secondary to benign tumor of the nasal dorsum]. / Deformidad de la pirámide nasal secundaria a tumoración benigna del dorso.

Describing the most relevant findings in the benign tumors of the nose, we present a case of cyst that eroded the dorsum of the nose and produced an aesthetic deformity. The treatment was a rhinoplasty operation including the removal of the cyst and the hump. After the anatomopathological findings we studied the different cysts, arriving at the concluding diagnosis that the cyst is sebaceus.

[Tracheobronchial foreign bodies in childhood]. / Cuerpos extraños traqueobronquiales en la infancia.

We report a clinical review of 1,980 cases of tracheobronchial foreign bodies in children aged between 0 months and 14 years old. In all of them the foreign bodies were removed through a rigid bronchoscope. The following conclusions arose: bronchoscopy in childhood must be done under general anesthesia. If the appropriate instruments, are not available, the removal of the foreign body must be postponed; the entire respiratory system must be explored during a bronchoscopy as it is likely to find multiple foreign bodies. We must insist that families keep potential foreign bodies out of reach from their children; in chronic respiratory diseases during childhood, the presence of a foreign body must be considered.