RESUMEN
You are asked to examine a 68-year-old woman with a 3-year history of multiple bilateral and largely asymptomatic white papules on her labia majora. Based on the history and photographs, what is your diagnosis?
Asunto(s)
Acantólisis/patología , Queratosis/patología , Enfermedades de la Vulva/diagnóstico , Anciano , Diagnóstico Diferencial , Femenino , HumanosRESUMEN
The gold standard for treatment of atopic dermatitis is topical corticosteroids. Parental alternative health beliefs and fear of topical corticosteroids may lead to non-adherence and treatment failure. At the extreme end, such beliefs may result in neglect constituting reportable child maltreatment. We examine the legal repercussions of such abuse in the criminal case resulting from the death of Gloria Sam.
Asunto(s)
Maltrato a los Niños , Dermatitis Atópica/tratamiento farmacológico , Padres/psicología , Administración Tópica , Corticoesteroides/administración & dosificación , Corticoesteroides/uso terapéutico , Niño , Maltrato a los Niños/legislación & jurisprudencia , Terapias Complementarias/legislación & jurisprudencia , Terapias Complementarias/psicología , Femenino , Humanos , Cumplimiento de la Medicación/psicología , Nueva Gales del Sur , Educación del Paciente como Asunto , Insuficiencia del TratamientoRESUMEN
A 7-year-old boy born to consanguineous parents had suffered from palmoplantar keratoderma and chronic gingivitis since the age of 3 months. He was diagnosed with Papillon-Lefèvre syndrome. Genetic testing confirmed that he was homozygous with a point mutation in exon 6 of the cathepsin C gene. One year after initiating treatment with acitretin 10 mg oral daily and trimethoprim-sulfamethoxazole, the patient's skin remains almost lesion-free, and he has new teeth that erupted during treatment and are free of periodontal disease.