[Changes in Plasmodium berghei berghei in mice maintained at high temperatures]. / Modification de Plasmodium berghei berghei chez la souris maintenue dans une atmosphère chaude.

The study of the evolution of Plasmodium berghei berghei is made in mice kept in a high temperature (35 degrees C) throughout the experiment. Some of these mouse parasites (less than 30%) show a gigantic atypical morphology. In the parasite growing in animals kept at 35 degrees C, the amount of DNA is higher than DNA rate of the parasites growing in control mice (20-22 degrees C). There is no evidence of any relation between the increase of DNA amount and the morphological modification of these parasites.

[Influence of a hot environmental temperature on the evolution of experimental paludism of the mouse with Plasmodium berghei berghei]. / Influence d'une ambiance thermique chaude sur l'évolution du paludisme expérimental de la souris à Plasmodium berghei berghei.

Swiss Mice infected with Plasmodium berghei berghei and maintained in permanence in a hot environmental temperature undergo a chronic infection whereas controls maintained at the laboratory temperature develop always an acute and lethal infection. The hot environmental temperature does not seem to have any action on the pathogenicity of the parasites. Host defences are stimulated.