Nonsteroidal anti-inflammatory drug-induced strictures of the colon: report of a case and review of the literature.

The phenomenon of strictures of the colon induced by nonsteroidal anti-inflammatory drugs is a newly recognized pathologic entity that has gained little exposure in the surgical literature to date. A further case is reported and the clinical features of this entity are discussed. Most patients present with symptoms suggestive of malignancy, namely anemia, obstructive symptoms, or weight loss. Pathologic changes are characterized by diaphragm-like strictures with submucosal fibrosis. Surgical resection to exclude malignancy and treat symptoms along with cessation of the nonsteroidal anti-inflammatory drug is the treatment of choice.

Acute streptococcal necrotising fasciitis.

Two cases of acute streptococcal necrotising fasciitis are reported. Both patients were taking nonsteroidal antiinflammatory drugs when they developed this infection. Urgent surgical debridement was undertaken and resulted in a successful outcome in both patients. The clinical and histopathological features of this condition are reviewed.

Thoracic empyema due to Streptococcus milleri: four cases.

Four cases of Streptococcus milleri empyema occurring over a six month period are reported. Empyema was post-pneumonic in three patients and followed blunt abdominal and chest trauma in one patient. There was an absence of serious underlying disease in these patients and management consisted of tube drainage, lavage of the pleural space and prolonged intrapleural and systemically administered antibiotic therapy. Complete recovery was achieved in three patients and a satisfactory result in the other without surgical intervention. The clinical and microbiological features of this group of patients are reviewed.