Relationship between severity of obsessive-compulsive symptoms and schizotypy in obsessive-compulsive disorder.

PURPOSE: Obsessive-compulsive disorder (OCD) patients exhibit a noninhibition response pattern very similar to that observed in schizotypy patients in cognitive tasks. It has been suggested that the reduced cognitive inhibition observed in both schizotypy and OCD may result in the frequent entry into awareness of unacceptable urges and intrusive thoughts. The aim of this study was to investigate the relationship between the severity of obsession or compulsion and schizotypy in OCD. PATIENTS AND METHODS: Sixty subjects (25 males and 35 females) who were OCD outpatients in the University Hospital at the Kyoto Prefectural University of Medicine during the period 2008-2010 were enrolled in the study. Assessments of these patients were made using the Yale-Brown Obsessive Compulsive Scale (Y-BOCS), the Schizotypal Personality Questionnaire (SPQ), the Hamilton Depression Rating Scale (HAM-D), and the Hamilton Anxiety Rating Scale (HAM-A). The Pearson correlation coefficients between Y-BOCS and SPQ scores were calculated. Furthermore, hierarchical multiple linear regression analyses were conducted to assess whether schizotypy predicted the severity of obsession and compulsion. RESULTS: By calculating the Pearson correlation coefficient, it was found that the Y-BOCS obsession score, not the Y-BOCS compulsion score, was correlated with the SPQ total score. Results of the hierarchical multiple linear regression analysis showed that SPQ total score was a significant predictor of the Y-BOCS obsession score, after accounting for control variables (ie, HAM-D and HAM-A). CONCLUSION: Results of this study showed that the Y-BOCS obsession score, not the Y-BOCS compulsion score, was correlated with the SPQ total score. This finding suggests that OCD patients with an elevated SPQ total score experience a reduction of cognitive inhibition, resulting in the frequent entry into obsession. Future longitudinal studies are recommended to clarify the effect of schizotypy on the clinical course of OCD.

Parental bonding in patients with eating disorders and self-injurious behavior.

AIM: The goal of the study was to investigate the correlations among parental bonding patterns, eating disorders (ED) and self-injurious behavior (SIB). METHODS: The subjects were 80 patients with ED who were divided into two groups based on those that had (n = 25) and had not engaged in SIB at least once in the last month. The patients and 120 healthy control subjects were evaluated using the Eating Disorder Inventory and the Parental Bonding Instrument. RESULTS: On the Parental Bonding Instrument, the ED + SIB group showed significantly lower paternal care compared with the ED/no SIB and control groups. On the Eating Disorder Inventory, the ED + SIB group showed higher body dissatisfaction, and increased maturity fear compared with the other two groups. The total scores and perfectionism and interoceptive awareness differed significantly among the three groups. CONCLUSION: ED + SIB patients had a more severe ED pathology than ED/no SIB patients, and also felt that they had received low paternal care during childhood. Therefore, paternal care may be linked to severe ED pathology.

Factors associated with postpartum depression and abusive behavior in mothers with infants.

AIMS: This study was conducted to examine factors associated with postpartum depression and abusive behavior in mothers with infants. METHODS: Data were collected from baby check-ups in Japan and 413 participants were included in an analysis using: (i) an Original Questionnaire; (ii) the Zung Self-rating Depression Scale (ZSDS); (iii) the Parental Bonding Instrument; and (iv) the Childcare Anxiety Scale (CAS). Covariance structural analyses were performed to examine interconnections among the Parental Bonding Instrument subscales, CAS subscales ('worry about parenting', 'burden of nursing time', 'difficulty of bonding'), ZSDS, 'fear of being abusive', and 'abusive behavior'. RESULTS: Of the 413 mothers, 14.5% showed higher than moderate levels of depression (ZSDS > or = 50). In covariance structural analyses, 'depression' was strongly influenced by 'worry about parenting' in all variances, but was not associated with 'abusive behavior'. 'Worry about parenting' also had a strong influence on 'fear of being abusive', but did not affect 'abusive behavior'. Low 'maternal care' had most influence on 'difficulty of bonding', and 'difficulty of bonding' only affected 'abusive behavior'. CONCLUSIONS: The outcome of this study suggests that excessive worrying related to postpartum depression, 'fear of being abusive', and bonding difficulty are primary predictors of child abuse. Postpartum depression was not a predictor for abusive behavior after exclusion of the impact of bonding difficulties on abusive behavior. Therefore, the correlation between postpartum depression and abusive behavior identified in previous reports may have been influenced by bonding difficulties.