1.
Biotechnol Appl Biochem
; 40(Pt 1): 107-11, 2004 Aug.
Artículo
en Inglés
| MEDLINE
| ID: mdl-15270714
RESUMEN
The effect of pH on cell growth and retamycin production in batch bioreactor cultures of Streptomyces olindensis ICB20 was investigated. In fermentations pH-controlled over the range 6.0-8.0, the highest retamycin production was achieved at pH 7.0, and the maximum concentration of retamycin, about 1.36 A (absorbance) units, was about 43, 58 and 232% higher than the values obtained at pH 7.5, 6.0 and 8.0 respectively.