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1.
Toxicology ; 413: 13-23, 2019 02 01.
Artículo en Inglés | MEDLINE | ID: mdl-30500381

RESUMEN

The Scientific Advisory Board (SAB) of the Organisation for the Prohibition of Chemical Weapons (OPCW) has provided advice in relation to the Chemical Weapons Convention on assistance and protection. We present the SAB's response to a request from the OPCW Director-General in 2014 for information on the best practices for preventing and treating the health effects from acute, prolonged, and repeated organophosphorus nerve agent (NA) exposure. The report summarises pre- and post-exposure treatments, and developments in decontaminants and adsorbing materials, that at the time of the advice, were available for NAs. The updated information provided could assist medics and emergency responders unfamiliar with treatment and decontamination options related to exposure to NAs. The SAB recommended that developments in research on medical countermeasures and decontaminants for NAs should be monitored by the OPCW, and used in assistance and protection training courses and workshops organised through its capacity building programmes.


Asunto(s)
Comités Consultivos/normas , Sustancias para la Guerra Química/toxicidad , Descontaminación/normas , Contramedidas Médicas , Agentes Nerviosos/toxicidad , Antídotos/uso terapéutico , Descontaminación/métodos , Humanos , Países Bajos , Compuestos Organofosforados/toxicidad , Resultado del Tratamiento
2.
RSC Adv ; 8(73): 41731-41739, 2018 Dec 12.
Artículo en Inglés | MEDLINE | ID: mdl-35558814

RESUMEN

Compounds that cause powerful sensory irritation to humans were reviewed by the Scientific Advisory Board (SAB) of the Organisation for the Prohibition of Chemical Weapons (OPCW) in response to requests in 2014 and 2017 by the OPCW Director-General to advise which riot control agents (RCAs) might be subject to declaration under the Chemical Weapons Convention (the "Convention"). The chemical and toxicological properties of 60 chemicals identified from a survey by the OPCW of RCAs that had been researched or were available for purchase, and additional chemicals recognised by the SAB as having potential RCA applications, were considered. Only 17 of the 60 chemicals met the definition of a RCA under the Convention. These findings were provided to the States Parties of the Convention to inform the implementation of obligations pertaining to RCAs under this international chemical disarmament and non-proliferation treaty.

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