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1.
Astrophys J Lett ; 868(2)2018 Dec 01.
Artículo en Inglés | MEDLINE | ID: mdl-31360431

RESUMEN

We report the detection of a transiting planet around π Men (HD 39091), using data from the Transiting Exoplanet Survey Satellite (TESS). The solar-type host star is unusually bright (V = 5.7) and was already known to host a Jovian planet on a highly eccentric, 5.7-year orbit. The newly discovered planet has a size of 2.04 ± 0.05 R ⊕ and an orbital period of 6.27 days. Radial-velocity data from the HARPS and AAT/UCLES archives also displays a 6.27-day periodicity, confirming the existence of the planet and leading to a mass determination of 4.82±0.85 M ⊕. The star's proximity and brightness will facilitate further investigations, such as atmospheric spectroscopy, asteroseismology, the Rossiter-McLaughlin effect, astrometry, and direct imaging.

2.
Sci Rep ; 6: 27972, 2016 06 21.
Artículo en Inglés | MEDLINE | ID: mdl-27323901

RESUMEN

The fruit fly Drosophila melanogaster is a widely used model for cell biology, development, disease, and neuroscience. The fly's power as a genetic model for disease and neuroscience can be augmented by a quantitative description of its behavior. Here we show that we can accurately account for the complex and unique crawling patterns exhibited by individual Drosophila larvae using a small set of four parameters obtained from the trajectories of a few crawling larvae. The values of these parameters change for larvae from different genetic mutants, as we demonstrate for fly models of Alzheimer's disease and the Fragile X syndrome, allowing applications such as genetic or drug screens. Using the quantitative model of larval crawling developed here we use the mutant-specific parameters to robustly simulate larval crawling, which allows estimating the feasibility of laborious experimental assays and aids in their design.


Asunto(s)
Biometría/métodos , Drosophila melanogaster/fisiología , Entomología/métodos , Locomoción , Fenotipo , Enfermedad de Alzheimer/patología , Animales , Modelos Animales de Enfermedad , Evaluación Preclínica de Medicamentos/métodos , Síndrome del Cromosoma X Frágil/patología , Pruebas Genéticas/métodos , Larva/fisiología
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