Glioblastoma: assessment of the readability and reliability of online information.

INTRODUCTION: Glioblastoma Multiforme (GBM) represents one of the most common and most aggressive forms of brain tumours with a poor prognosis. There is often uncertainty around diagnosis and prognosis amongst patients diagnosed with cancer. Most patients rely on internet to access health-related information. The aim of this study was to assess the readability and reliability of online information on GBM. METHODS: The terms 'Glioblastoma' and 'GBM' were used to search Google and the first 50 websites identified were screened. For each website, the quality of each website was assessed using the DISCERN instrument, the Journal of the American Medical Association (JAMA) benchmark criteria and the Health on the Net Foundation code certification (HON-code). The readability was assessed using the Flesch Reading Ease Score (FRE), the Flesch-Kincaid grade level (FKGL) and the Gunning Fog Index (GFI). The relevant patient information by 4 International patient information websites were also assessed. RESULTS: Following screening, 31 websites met the inclusion criteria with only four websites displaying the HON-code (12.9%). The median DISCERN score was 43 (range: 17-70) corresponding to 'fair' quality, and the median JAMA benchmark criteria score was 1. Display of the HON-code certificate or the publication date was associated with higher quality websites. The median FRE score corresponded to 'difficult' to read (34.4). The median GFI score (15.9) and FKGL score (13.3) corresponded to a 'college' level of education reading ability. The Cancer Australia online information was the most readable website while Cancer Research UK had the highest quality information. CONCLUSION: The readability and reliability of online information relating to GBM is inadequate. Health professionals need to provide or guide patients to information that is both readable and reliable.

Cranioplasty outcomes and associated complications: A single-centre observational study.

INTRODUCTION: The resurgence of decompressive craniectomy has led to recent published reviews of the safety of cranioplasties. To date there is a wide range of reported mortality and morbidity. This observational study reports the outcomes of the cranioplasty operations from a single centre and evaluates the factors involved in their management. METHODS: A retrospective search of all theatre logs was performed for the years 2006-2013 inclusive. 88 operations were documented as 'Cranioplasty'. Data collection include patient demographics, type of cranioplasty used, time lapse between decompression and cranioplasty, seniority of the operating surgeon(s), antibiotic regimen and complications. Outcomes were recorded at the three-month follow-up. RESULTS: The overall complication rate was 6.8%. The mean patient age was 36.2 years. 52.2% of patients had decompressive craniectomy for trauma, 11.3% had infectious pathology, 9% had subarachnoid haemorrhage, 9% had tumour with bone infiltration and 3.4% had stroke. 55.7% of patients had cranioplasty within 6 months of craniectomy. 61.3% of cranioplasties were with autologous bone, 20.4% titanium, 10.2% acrylic and 7.9% polyetheretherketone (PEEK). Significant complications included one case of infection, two cases of subgaleal haematoma and one extradural collection. No deaths were noted. No correlation was found between infection and the use of drains. 68.6% of cases were done by either a senior surgeon or a supervised registrar. There was an observable difference in complication rates in relation to the seniority and experience of the operator. However, patient numbers and complications were insufficient to achieve statistical significance. Strict antimicrobial prescribing was observed. CONCLUSION: Some potentially preventable complications have been addressed with a resulting rate of complications lower than other published reports. We use two standard adjuncts: the presence of a senior surgeon and strict antimicrobial regimens. We believe that our results could be transferrable to other units by following similar guidelines.