RESUMEN
Oculocutaneous albinism is a genetically heterogeneous, autosomal recessive group of disorders characterized by a generalized decreased or absence of melanin pigment in the eyes, hair, and skin. These patients have a greater sensitivity to UV radiation and a predisposition to skin tumors, mainly squamous cell carcinoma and basal cell carcinomas, and to a lesser extent malignant melanomas. Melanoma can be one of the most challenging cancers to diagnose in patients with albinism. We report an uncommon clinical presentation of melanoma, an amelanotic melanoma in the right supraciliar region in a patient with oculocutaneous albinism. The clinical presentation was an erythematous, scaly and ill-defined plaque. The skin biopsy revealed a lentigo maligna melanoma. Amelanotic melanomas are one of the two most difficult to diagnose subtypes of melanoma, together with the nevoid type. Melanoma in oculocutaneous albinism patients are often amelanotic, which makes their clinical diagnosis very difficult. These patients should be examined in the dermatology department at least once a year and it is recommended to have a high index of suspicion.
Asunto(s)
Albinismo Oculocutáneo/complicaciones , Melanoma Amelanótico/patología , Neoplasias Cutáneas/patología , Adolescente , Adulto , Anciano , Anciano de 80 o más Años , Niño , Dermoscopía , Femenino , Humanos , Lactante , Masculino , Melanoma Amelanótico/complicaciones , Melanoma Amelanótico/diagnóstico , Persona de Mediana Edad , Neoplasias Cutáneas/complicaciones , Neoplasias Cutáneas/diagnósticoRESUMEN
Palisaded encapsulated neuroma is a rare, benign neural tumor. The involvement of the glans penis is rare; few cases have been reported. We present a 52-year-old man with a five-month course of a solitary painless lesion of the glans penis. Full excision of the nodule was performed. Histopathological and immunohistochemical analyses and examination was consistent with a palisaded encapsulated neuroma. We describe one of a few existing cases of this kind of tumor in the glans penis.
Asunto(s)
Neuroma/patología , Neoplasias del Pene/patología , Pene/patología , Diagnóstico Diferencial , Humanos , Masculino , Persona de Mediana Edad , Neuroma/diagnóstico , Neoplasias del Pene/diagnósticoRESUMEN
No disponible
No disponible
Asunto(s)
Humanos , Masculino , Anciano , Actinomicosis Cervicofacial/diagnóstico , Labio/microbiología , Actinomyces/patogenicidad , Diagnóstico DiferencialRESUMEN
La lipoatrofia semicircular de los muslos es una forma de lipodistrofia localizada poco frecuente caracterizada por unas depresiones horizontales semicirculares a modo de banda, asintomáticas, a menudo bilaterales y simétricas localizadas en la cara anterolateral de los muslos. Su etiopatogenia es desconocida, aunque la mayoría de los casos se asocian a traumatismos de repetición. Una nueva hipótesis implicaría como causa los campos electromagnéticos generados por los ordenadores y sus cables en los edificios modernos. Describimos el caso de una mujer de 28 años que presentaba esta entidad relacionada con el uso de pantalones ajustados (AU)
Lipoatrophia semicircularis of the thighs is an uncommon form of localized lipodystrophy characterized by horizontal semicircular depressions distributed to form a band. The asymptomatic, often bilateral, and symmetric lesions are localized on the anterolateral aspect of the thighs. The pathogenesis of these lesions is unknown, although most cases are associated with repetitive trauma. A new hypothesis has implicated electromagnetic fields produced by computers and their cables in modern buildings as a cause. We describe a case in a 28-year-old woman of lipoatrophia semicircularis that was related to wearing tight pants (AU)
Asunto(s)
Humanos , Femenino , Adulto , Lipodistrofia/complicaciones , Lipodistrofia/diagnóstico , Campos Electromagnéticos/efectos adversos , Atrofia/complicaciones , Atrofia/diagnóstico , Inmunohistoquímica/métodos , Dermatosis de la Pierna/complicaciones , Dermatosis de la Pierna/diagnóstico , Atrofia Muscular/complicaciones , Atrofia Muscular/diagnóstico , Adipocitos/patología , Adipocitos/ultraestructura , Servicios de Salud del Trabajador/normas , Riesgos Laborales , Exposición Profesional/efectos adversos , Dermatitis Profesional/diagnósticoRESUMEN
Lipoatrophia semicircularis of the thighs is an uncommon form of localized lipodystrophy characterized by horizontal semicircular depressions distributed to form a band. The asymptomatic, often bilateral, and symmetric lesions are localized on the anterolateral aspect of the thighs. The pathogenesis of these lesions is unknown, although most cases are associated with repetitive trauma. A new hypothesis has implicated electromagnetic fields produced by computers and their cables in modern buildings as a cause. We describe a case in a 28-year-old woman of lipoatrophia semicircularis that was related to wearing tight pants.