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2.
J Reprod Fertil ; 57(1): 91-5, 1979 Sep.
Artículo en Inglés | MEDLINE | ID: mdl-513011

RESUMEN

Transport of embryos through the oviduct, cleavage rate and transformation of morulae to blastocysts, were delayed in females ovariectomized on Day 2 of pregnancy. Oestradiol-17 beta in doses of 60 to 6000 pg/day for 3 days did not normalize the transport of embryos, but the transformation of morulae to blastocysts reached values near or equal to those of the controls, in spite of a lowered rate of cleavage. Progesterone at a dose of 100 micrograms/day, resulted in normal transport, rate of cleavage and rate of differentiation. Treatment with both hormones had synergistic effects on transport and the rate of cleavage and differentiation. These results give further support to the concept that ovarian hormones are the controlling factors for these processes in early pregnancy.


Asunto(s)
Embrión de Mamíferos/efectos de los fármacos , Estradiol/farmacología , Trompas Uterinas/fisiología , Transporte del Óvulo/efectos de los fármacos , Progesterona/farmacología , Animales , Blastómeros/efectos de los fármacos , Castración , Sinergismo Farmacológico , Trompas Uterinas/efectos de los fármacos , Femenino , Ratones , Mórula/efectos de los fármacos , Embarazo
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