Impact of Pleural Lavage Cytology Positivity on Early Recurrence After Surgery for Non-Small Cell Lung Cancer.

OBJECTIVE: The aim of this study was to elucidate the impact of pleural lavage cytology positivity on early recurrence in patients operated on non-small cell lung cancer (NSCLC). METHODS: This is a multicentre prospective cohort study of 684 patients undergoing an anatomical lung resection for NSCLC between October 2015 and October 2017 at 12 national centres. A pleural lavage was performed before and after lung resection. The association between the different predictors of early recurrence and PLC positivity was performed using univariate and multivariate logistic regression models. A propensity score analysis was performed by inverse probability weighting (IPSW) using average treatment effect (ATE) estimation to analyse the impact of PLC positivity on early recurrence. RESULTS: Overall PLC positivity was observed in 15 patients (2.2%). After two years, 193 patients (28.2%) relapsed, 182 (27.2%) with a negative PLC and 11 (73.3%) with a positive PLC (p<0.001). Factors associated to early recurrence were adenocarcinoma histology (OR=1.59, 95%CI 1.06-2.38, p=0.025), visceral pleural invasion (OR=1.59, 95%CI 1.04-2.4, p=0.03), lymph node involvement (OR=1.84, 95%CI 1.14-2.96, p=0.013), advanced pathological stage (OR=2.12, 95%CI 1.27-3.54, p=0.004) and PLC positivity (OR=4.14, 95%CI 1.25-16.36, p=0.028). After IPSW, PLC positivity was associated with an increased risk of early recurrence (OR=3.46, 95%CI 2.25-5.36, p<0.001). CONCLUSIONS: Positive pleural lavage cytology was found to be the strongest predictor of early recurrence.

Infarto hemorrágico espontáneo de nódulo tiroideo / Spontaneous hemorrhagic infarction of thyroid nodule

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La Anatomía Patológica en las redes sociales. Campaña de reclutamiento / Pathology in social media networks. Recruitment campaign

Introducción. La Anatomía Patológica sigue siendo desconocida, no solo para el público en general, sino también para nuestros compañeros de profesión. El uso generalizado de las redes sociales permite difundir nuestra labor. Por ello, se planteó generar un grupo de trabajo. Material y métodos. Se emitió una convocatoria a los socios de la Sociedad Española de Anatomía Patológica a través de su Vocalía de Comunicación y Proyección Social titulada #IWantYouForSEAP, para conformar una red de trabajo en la red social Twitter. El periodo de reclutamiento fue de un mes (agosto del 2016). Se registró la actividad desarrollada durante el XXVIII Congreso de la SEAP-IAP de 2017 utilizando las herramientas analíticas Symplur y Tweet Binder. Resultados. Se recibieron 32 solicitudes (29 patólogos, 2 técnicos de Anatomía Patológica, un administrativo), con una distribución geográfica dentro del territorio español que incluyó a participantes de 14 de las 17 comunidades autónomas, perteneciendo a 22 ciudades y 25 centros distintos. La actividad en relación con el hashtag #SEAP2017V utilizado en el congreso incluyó a 685 participantes, 6.704 tweets y 8.837.435 impresiones; 28 de los 32 reclutados por la campaña #IWantYouForSEAP participaron, contribuyendo con 2.410 tweets y generando 2.090.423 impresiones (el 36 y el 24% del total, respectivamente). Conclusiones. Es posible promover y motivar el trabajo en grupo dentro de nuestra disciplina a través de las redes sociales. Se trata de una fase inicial, pero los resultados experimentados son alentadores y existen grandes expectativas por parte de los participantes. Un uso adecuado de las redes sociales podría acercar la figura del patólogo a la sociedad (AU)

Introduction. Pathology is a speciality that is often poorly understood, not only by the general public, but also by clinicians. However, the recent widespread use of social media provides an opportunity to increase the visibility and comprehension of our profession. A working group was formed to carry out this task. Material and methods. The members of the Spanish Society of Pathology were contacted through its Communication and Social Projection Subcommittee to engage in the campaign #IWantYouForSEAP, to form a network on Twitter. The recruitment period was one month (August, 2016). The resulting project, developed during the XXVIII Congress of the SEAP-IAP, was registered using the analytical tools Symplur and Tweet Binder. Results. 32 applications (29 pathologists, 2 histotechnicians, 1 administrative personnel) were received from all over Spain, including participants from 14 of the 17 Autonomous Regions, from 22 cities and 25 medical centres. The activity in relation to the hashtag #SEAP2017V used in the congress included 685 participants with 6704 tweets and 8,837,435 impressions. 28 of the 32 recruited by the #IWantYouForSEAP campaign participated, contributing with 2410 tweets, and generating 2,090,423 impressions (36% and 24% of the total, respectively). Conclusions. It is possible to promote and motivate teamwork within our discipline through social media networks. This preliminary experience of the use of social media networks in our scientific community has had encouraging results which have raised high expectations among participants. An appropriate use of social media networks could help to narrow the gap between pathologists and society (AU)

[Pathology in social media networks. Recruitment campaign]. / La Anatomía Patológica en las redes sociales. Campaña de reclutamiento.

INTRODUCTION: Pathology is a speciality that is often poorly understood, not only by the general public, but also by clinicians. However, the recent widespread use of social media provides an opportunity to increase the visibility and comprehension of our profession. A working group was formed to carry out this task. MATERIAL AND METHODS: The members of the Spanish Society of Pathology were contacted through its Communication and Social Projection Subcommittee to engage in the campaign #IWantYouForSEAP, to form a network on Twitter. The recruitment period was one month (August, 2016). The resulting project, developed during the XXVIII Congress of the SEAP-IAP, was registered using the analytical tools Symplur and Tweet Binder. RESULTS: 32 applications (29 pathologists, 2 histotechnicians, 1 administrative personnel) were received from all over Spain, including participants from 14 of the 17 Autonomous Regions, from 22 cities and 25 medical centres. The activity in relation to the hashtag #SEAP2017V used in the congress included 685 participants with 6704 tweets and 8,837,435 impressions. 28 of the 32 recruited by the #IWantYouForSEAP campaign participated, contributing with 2410 tweets, and generating 2,090,423 impressions (36% and 24% of the total, respectively). CONCLUSIONS: It is possible to promote and motivate teamwork within our discipline through social media networks. This preliminary experience of the use of social media networks in our scientific community has had encouraging results which have raised high expectations among participants. An appropriate use of social media networks could help to narrow the gap between pathologists and society.

Leishmaniasis laríngea, modificación quirúrgica tras estudio intraoperatorio. Comunicación de un caso / Modified surgical procedure following intraoperative frozen section of laringeal leishmaniasis. A case report

La leishmaniasis es una metazoonosis crónica de distribución mundial que está producida por cualquier integrante del género Leishmania, y su infección afecta la piel, las mucosas o las vísceras. Presentamos el caso de un varón de 67 años con disfonía y disfagia, valorado por el servicio de otorrinolaringología, quienes realizaron cirugía laríngea sospechando un carcinoma y solicitaron un estudio intraoperatorio que evidenció ausencia de malignidad y la presencia de microorganismos intracelulares. Por este motivo se suspendió la cirugía. Al ser una enfermedad endémica en España, conviene tener presente la leishmaniasis entre los diagnósticos diferenciales de las lesiones excrecentes de la laringe para evitar actitudes quirúrgicas agresivas(AU)

Leishmaniasis is a chronic metazoonosis caused by any member of the genus Leishmania and occurs throughout the world. Infection affects the skin, mucous membranes and viscera. We report a case in a 67 year old man with dysphonia and dysphagia who underwent surgery for suspected laryngeal carcinoma. Intraoperative frozen section revealed no malignancy and the presence of intracellular organisms and no further surgery was performed. As leishmaniasis is endemic in Spain, it should be included in the differential diagnosis of excrescent lesions of the larynx in order to prevent unnecessary surgery(AU)