Physical training program for people at risk of cardiovascular disorders in the primary care setting: A randomized clinical trial

Background and Objective: The impact of a physical training program on moderate–vigorous physical activity is still poorly known in primary cardiovascular prevention. Our objective was to determine the efficacy of a physical training program to promote moderate–vigorous physical activity and exercise in individuals at risk of suffering a cardiovascular event.Patients and methodsRandomized, parallel group controlled trial performed from October 2014 to July 2016. Sedentary patients at risk of suffering a cardiovascular event were randomized to the control group (CG) (72) or the intervention group (IG) (75). Intervention consisted of a 2-month physical training program. The main outcome was the proportion of patients achieving a “relevant response to Physical Activity” (increase≥240METs-min/week in moderate–vigorous Physical Activity using the International Physical Activity Questionnaire (IPAQ)). Secondary outcomes included the proportion of patients performing an “adequate amount of exercise” (≥360METs-min/week in moderate–vigorous exercise using the IPAQ).ResultsOf the 147 patients randomized, 132 (90%) completed the follow-up. Adherence to exercise performance was 91% and no adverse effects were recorded. The proportion of patients in the IG versus CG achieving the main outcome was 34.9% vs 11.6%; OR [95%CI]: 4.2 [1.7–10.4]. Furthermore, more patients in the IG performed an adequate amount of exercise (33.3% vs. 11.6%; OR: 4.1 [1.6–10.5]).ConclusionA short-duration physical training program performed in the primary care setting is efficacious and safe in promoting moderate–vigorous physical activity and exercise in the short-term, in a population at risk of suffering a cardiovascular event. (AU)

Antecedentes y objetivo: El impacto de programas de entrenamiento en actividad física moderada-vigorosa es poco conocido en prevención primaria cardiovascular. Nuestro objetivo fue analizar la eficacia de un programa de entrenamiento en promover la actividad física moderada-vigorosa y la práctica de ejercicio, en pacientes con riesgo de eventos cardiovasculares.Pacientes y métodoEnsayo clínico aleatorizado, paralelo, con grupo control (octubre 2014 a julio 2016). Pacientes sedentarios con riesgo de eventos cardiovasculares se aleatorizaron a un grupo control (GC) (72) o un grupo intervención (GI) (75). La intervención consistió en un programa de entrenamiento de 2meses. La variable pronóstica principal fue la proporción de pacientes que alcanzaron una «respuesta relevante en actividad física» (aumento≥240MET-min/sem actividad física moderada-vigorosa en el Cuestionario Internacional de Actividad Física [International Physical Activity Questionnaire, IPAQ]). Las variables pronósticas secundarias incluyeron la proporción de pacientes que realizaban una «adecuada cantidad de ejercicio»(≥360MET-min/sem ejercicio moderado-vigoroso en el IPAQ).ResultadosDe los 147 pacientes aleatorizados, 132 (90%) completaron el seguimiento. La adherencia a las sesiones fue del 91% y no se registraron efectos adversos. La proporción de pacientes en GI versus GC que alcanzaron el objetivo principal fue del 34,9% vs el 11,6%; OR: 4,2; IC 95%: 1,7-10,4. Significativamente más pacientes en el GI realizaron una adecuada cantidad de ejercicio (33,3% vs 11,6%; OR: 4,1; IC 95%: 1,6-10,5).ConclusiónUn programa de entrenamiento de corta duración realizado en atención primaria es eficaz y seguro a corto plazo en la promoción de la actividad física moderada-vigorosa y del ejercicio en una población con riesgo de eventos cardiovasculares. (AU)

Physical training program for people at risk of cardiovascular disorders in the primary care setting: A randomized clinical trial.

BACKGROUND AND OBJECTIVE: The impact of a physical training program on moderate-vigorous physical activity is still poorly known in primary cardiovascular prevention. Our objective was to determine the efficacy of a physical training program to promote moderate-vigorous physical activity and exercise in individuals at risk of suffering a cardiovascular event. PATIENTS AND METHODS: Randomized, parallel group controlled trial performed from October 2014 to July 2016. Sedentary patients at risk of suffering a cardiovascular event were randomized to the control group (CG) (72) or the intervention group (IG) (75). Intervention consisted of a 2-month physical training program. The main outcome was the proportion of patients achieving a "relevant response to Physical Activity" (increase≥240METs-min/week in moderate-vigorous Physical Activity using the International Physical Activity Questionnaire (IPAQ)). Secondary outcomes included the proportion of patients performing an "adequate amount of exercise" (≥360METs-min/week in moderate-vigorous exercise using the IPAQ). RESULTS: Of the 147 patients randomized, 132 (90%) completed the follow-up. Adherence to exercise performance was 91% and no adverse effects were recorded. The proportion of patients in the IG versus CG achieving the main outcome was 34.9% vs 11.6%; OR [95%CI]: 4.2 [1.7-10.4]. Furthermore, more patients in the IG performed an adequate amount of exercise (33.3% vs. 11.6%; OR: 4.1 [1.6-10.5]). CONCLUSION: A short-duration physical training program performed in the primary care setting is efficacious and safe in promoting moderate-vigorous physical activity and exercise in the short-term, in a population at risk of suffering a cardiovascular event. TRIAL REGISTRATION: "Training Programme in Physical Activity". NCT03717363. TRIAL REGISTRATION: Clinicaltrials.gov.