[Estimation of overall cardiovascular risk from coronary risk. A cohort study]. / Estimación del riesgo cardiovascular global a partir del riesgo coronario. Estudio de cohortes.

BACKGROUND AND OBJECTIVE: The coronary risk (CR) is a good approximation of the global cardiovascular risk (GCR). Multiplying the CR per 1.3 we obtain the GCR, but we don't know if it is certain in our country. PATIENTS AND METHOD: Prospective cohort study with 851 patients of ages between 35-74 years old, without cardiovascular disease and followed during 5 years. CR include myocardial ischemia (angor pectoris or myocardial infarction). GCR include CR, cerebrovascular disease, and peripheral vascular disease. RESULTS: We registered 21 myocardial ischemia cases, 15 cerebrovascular disease cases and 8 peripheral vascular disease cases. The accumulated incidence was: 2.5% for CR and 5.2% for GCR (difference 2.7%; 95% confidence interval for the difference 0.9-4.6%; p < 0.05). To estimated GCR we should multiple CR per 2.1. CONCLUSIONS: CR is not a good approximation of GCR. We need to developed equation that include not only CR but also GCR.

Estimación del riesgo cardiovascular global a partir del riesgo coronario. Estudio de cohortes / Estimation of overall cardiovascular risk from coronary risk. A cohort study

Fundamento y objetivo: Se considera que el riesgo coronario (RC) es una buena aproximación al riesgo cardiovascular global (RCG). Si se multiplica el RC por 1,3, se obtendría el RCG, pero desconocemos si esto es cierto en España. Pacientes y método: Estudio de cohorte prospectiva, con 851 pacientes de 35-74 años sin enfermedades cardiovasculares, seguidos durante 5 años. El RC incluyó la cardiopatía isquémica (angina o infarto agudo de miocardio) y el RCG, el RC más la enfermedad cerebrovascular y la arteriopatía periférica de extremidades inferiores. Resultados: Se registró 21 casos de cardiopatía isquémica, 15 de enfermedad cerebrovascular y 8 de arteriopatía periférica. La incidencia acumulada fue del 2,5% para el RC y el 5,2% para el RCG (diferencia del 2,7%; intervalo de confianza del 95% de la diferencia, 0,9-4,6%; p < 0,05). Para estimar el RCG tendríamos que multiplicar el RC por 2,1. Conclusiones: El RC no es una buena aproximación al RCG. Es preciso desarrollar ecuaciones que incluyan el RCG y no sólo el RC

Background and objective: The coronary risk (CR) is a good approximation of the global cardiovascular risk (GCR). Multiplying the CR per 1.3 we obtain the GCR, but we don't know if it is certain in our country. Patients and method: Prospective cohort study with 851 patients of ages between 35-74 years old, without cardiovascular disease and followed during 5 years. CR include myocardial ischemia (angor pectoris or myocardial infarction). GCR include CR, cerebrovascular disease, and peripheral vascular disease. Results: We registered 21 myocardial ischemia cases, 15 cerebrovascular disease cases and 8 peripheral vascular disease cases. The accumulated incidence was: 2.5% for CR and 5.2% for GCR (difference 2.7%; 95% confidence interval for the difference 0.9-4.6%; p < 0.05). To estimated GCR we should multiple CR per 2.1. Conclusions: CR is not a good approximation of GCR. We need to developed equation that include not only CR but also GCR